(Q40625024)

English

Enhanced intracellular availability and survival of hammerhead ribozymes increases target ablation in a cellular model of osteogenesis imperfecta

scientific article published on November 2003

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scholarly article

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Europe PubMed Central

PubMed publication ID

22 September 2017

Enhanced intracellular availability and survival of hammerhead ribozymes increases target ablation in a cellular model of osteogenesis imperfecta (English)

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

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osteogenesis imperfecta

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author name string

Smicun Y

1

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PubMed publication ID

22 September 2017

Kilpatrick MW

2

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Europe PubMed Central

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22 September 2017

Florer J

3

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Toudjarska I

4

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Wu G

5

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Wenstrup RJ

6

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22 September 2017

Tsipouras P

7

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Europe PubMed Central

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22 September 2017

language of work or name

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publication date

1 November 2003

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22 September 2017

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Europe PubMed Central

PubMed publication ID

22 September 2017

10

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22 September 2017

24

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22 September 2017

2005-2012

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22 September 2017

https://scigraph.springernature.com/pub.10.1038/sj.gt.3302108

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Simple RNA enzymes with new and highly specific endoribonuclease activities

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Self-cleavage of plus and minus RNAs of a virusoid and a structural model for the active sites

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Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme

1 reference

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Ribozyme rescue of photoreceptor cells in a transgenic rat model of autosomal dominant retinitis pigmentosa.

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Effective reversal of a transformed phenotype by retrovirus-mediated transfer of a ribozyme directed against mutant N-ras

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A mutation-independent therapeutic strategem for osteogenesis imperfecta

1 reference

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

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RNAi: nature abhors a double-strand

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Type I osteogenesis imperfecta: a nonfunctional allele for pro alpha 1 (I) chains of type I procollagen

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Perinatal lethal osteogenesis imperfecta in transgenic mice bearing an engineered mutant pro-alpha 1(I) collagen gene

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Transgenic mouse model of the mild dominant form of osteogenesis imperfecta

1 reference

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Defective pro alpha 2(I) collagen synthesis in a recessive mutation in mice: a model of human osteogenesis imperfecta

1 reference

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Use of the Cre/lox recombination system to develop a non-lethal knock-in murine model for osteogenesis imperfecta with an alpha1(I) G349C substitution. Variability in phenotype in BrtlIV mice

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Transgenic mice expressing a partially deleted gene for type I procollagen (COL1A1). A breeding line with a phenotype of spontaneous fractures and decreased bone collagen and mineral

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Phenotypic variability and incomplete penetrance of spontaneous fractures in an inbred strain of transgenic mice expressing a mutated collagen gene (COL1A1)

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Discordant expression of osteoblast markers in MC3T3-E1 cells that synthesize a high turnover matrix

1 reference

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21 January 2018

Delivery of a hammerhead ribozyme specifically downregulates mutant type I collagen mRNA in a murine model of osteogenesis imperfecta

1 reference

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Poxviruses as expression vectors

1 reference

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Regulation of mRNA stability in mammalian cells

1 reference

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Poxvirus vectors: orphaned and underappreciated

1 reference

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Infection control in gene therapy

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Retroviral vectors produced in the cytoplasmic vaccinia virus system transduce intron-containing genes

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Host range and cytopathogenicity of the highly attenuated MVA strain of vaccinia virus: propagation and generation of recombinant viruses in a nonhuman mammalian cell line

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A small catalytic oligoribonucleotide

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Delivery of a hammerhead ribozyme specifically down-regulates the production of fibrillin-1 by cultured dermal fibroblasts

1 reference

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based on heuristic

inferred from DOI database lookup

Hammerhead ribozymes targeted to the FBN1 mRNA can discriminate a single base mismatch between ribozyme and target

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Design and preparation of a multimeric self-cleaving hammerhead ribozyme

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Reversal of inhibition by the T7 concatemer junction sequence on expression from a downstream T7 promoter

1 reference

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7 January 2021

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Vaccinia virus for human gene therapy.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.GT.3302108

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Dimensions Publication ID

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

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