(Q40626878)

English

Structural analysis of the unmutated ancestor of the HIV-1 envelope V2 region antibody CH58 isolated from an RV144 vaccine efficacy trial vaccinee

scientific article published on 20 June 2015

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

22 September 2017

Structural analysis of the unmutated ancestor of the HIV-1 envelope V2 region antibody CH58 isolated from an RV144 vaccine efficacy trial vaccinee (English)

1 reference

Europe PubMed Central

PMC publication ID

22 September 2017

Jaranit Kaewkungwal

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22 September 2017

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Barton F Haynes

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22 September 2017

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Merlin L Robb

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Europe PubMed Central

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22 September 2017

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Nelson L Michael

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Europe PubMed Central

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22 September 2017

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Jerome H Kim

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22 September 2017

Supachai Rerks-Ngarm

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Supachai Rerks-Ngarm

1 reference

Europe PubMed Central

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22 September 2017

Nathan I Nicely

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object named as

Nathan I Nicely

1 reference

Europe PubMed Central

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22 September 2017

Thomas B. Kepler

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Thomas B Kepler

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Europe PubMed Central

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22 September 2017

Sorachai Nitayaphan

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object named as

Sorachai Nitayaphan

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Europe PubMed Central

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22 September 2017

Punnee Pitisuttithum

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Punnee Pitisuttithum

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Europe PubMed Central

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22 September 2017

S Moses Dennison

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S Moses Dennison

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Europe PubMed Central

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22 September 2017

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S Munir Alam

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Europe PubMed Central

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22 September 2017

Mattia Bonsignori

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Mattia Bonsignori

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Europe PubMed Central

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22 September 2017

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object named as

Kevin Wiehe

1 reference

Europe PubMed Central

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22 September 2017

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object named as

Hua-Xin Liao

1 reference

Europe PubMed Central

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22 September 2017

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object named as

Kwan-Ki Hwang

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22 September 2017

author name string

Frederick H Jaeger

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Europe PubMed Central

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22 September 2017

Robert J O'Connell

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Europe PubMed Central

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22 September 2017

publication date

20 June 2015

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Europe PubMed Central

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22 September 2017

1 reference

Europe PubMed Central

PMC publication ID

22 September 2017

2

1 reference

Europe PubMed Central

PMC publication ID

22 September 2017

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Europe PubMed Central

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22 September 2017

713-722

1 reference

Europe PubMed Central

PMC publication ID

22 September 2017

Antibody light-chain-restricted recognition of the site of immune pressure in the RV144 HIV-1 vaccine trial is phylogenetically conserved

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4534707

22 September 2017

Structure and immune recognition of trimeric pre-fusion HIV-1 Env.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4534707

22 September 2017

Cryptic determinant of α4β7 binding in the V2 loop of HIV-1 gp120.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4534707

22 September 2017

Affinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4534707

22 September 2017

Capacity for infectious HIV-1 virion capture differs by envelope antibody specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4534707

22 September 2017

Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4534707

22 September 2017

The HIV-1 envelope protein gp120 impairs B cell proliferation by inducing TGF-β1 production and FcRL4 expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4534707

22 September 2017

Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4534707

22 September 2017

HIV-1 neutralizing antibodies: understanding nature's pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4534707

22 September 2017

Structural basis for diverse N-glycan recognition by HIV-1–neutralizing V1–V2–directed antibody PG16

1 reference

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22 September 2017

Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4534707

22 September 2017

Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4534707

22 September 2017

Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4534707

22 September 2017

The Thai Phase III HIV Type 1 Vaccine trial (RV144) regimen induces antibodies that target conserved regions within the V2 loop of gp120.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4534707

22 September 2017

Human antibodies that neutralize HIV-1: identification, structures, and B cell ontogenies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4534707

22 September 2017

Increased HIV-1 vaccine efficacy against viruses with genetic signatures in Env V2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4534707

22 September 2017

Antibody-dependent cellular cytotoxicity-mediating antibodies from an HIV-1 vaccine efficacy trial target multiple epitopes and preferentially use the VH1 gene family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4534707

22 September 2017

Immune-correlates analysis of an HIV-1 vaccine efficacy trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4534707

22 September 2017

Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4534707

22 September 2017

Differential reactivity of germ line allelic variants of a broadly neutralizing HIV-1 antibody to a gp41 fusion intermediate conformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4534707

22 September 2017

Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4534707

22 September 2017

Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4534707

22 September 2017

Crystal structure of a non-neutralizing antibody to the HIV-1 gp41 membrane-proximal external region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4534707

22 September 2017

A new clustering of antibody CDR loop conformations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4534707

22 September 2017

Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4534707

22 September 2017

Features and development of Coot

1 reference

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22 September 2017

PHENIX: a comprehensive Python-based system for macromolecular structure solution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4534707

22 September 2017

Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4534707

22 September 2017

The role of dynamic conformational ensembles in biomolecular recognition

1 reference

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22 September 2017

Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4534707

22 September 2017

Crystallographic model quality at a glance

1 reference

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22 September 2017

Multi-constraint computational design suggests that native sequences of germline antibody H3 loops are nearly optimal for conformational flexibility

1 reference

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22 September 2017

HIV-1 envelope protein binds to and signals through integrin α4β7, the gut mucosal homing receptor for peripheral T cells

1 reference

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22 September 2017

Iterative model building, structure refinement and density modification with the PHENIX AutoBuild wizard

1 reference

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22 September 2017

The role of antibody polyspecificity and lipid reactivity in binding of broadly neutralizing anti-HIV-1 envelope human monoclonal antibodies 2F5 and 4E10 to glycoprotein 41 membrane proximal envelope epitopes

1 reference

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22 September 2017

A group M consensus envelope glycoprotein induces antibodies that neutralize subsets of subtype B and C HIV-1 primary viruses

1 reference

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22 September 2017

Antibody evolution constrains conformational heterogeneity by tailoring protein dynamics

1 reference

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Structure validation by Calpha geometry: phi,psi and Cbeta deviation

1 reference

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Flexibility and molecular recognition in the immune system.

1 reference

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22 September 2017

Conformational isomerism and the diversity of antibodies

1 reference

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22 September 2017

Solvent content of protein crystals

1 reference

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Key mutations stabilize antigen-binding conformation during affinity maturation of a broadly neutralizing influenza antibody lineage

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Envelope glycoprotein binding to the integrin α4β7 is not a general property of most HIV-1 strains

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Crystallization of intact monoclonal antibodies.

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20 August 2018

Antibody dissociation rates are predictive of neutralizing antibody (NAb) course: A comparison of interferon beta-1b-treated Multiple Sclerosis (MS) patients with transient versus sustained NAbs

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Maturation of an antibody response is governed by modulations in flexibility of the antigen-combining site

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Critical amino acid residues of the alpha4 subunit for alpha4beta7 integrin function

1 reference

https://pubmed.ncbi.nlm.nih.gov/26288844

12 December 2020

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Processing of X-ray diffraction data collected in oscillation mode

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https://pubmed.ncbi.nlm.nih.gov/26288844

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based on heuristic

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Identifiers

10.1016/J.EBIOM.2015.06.016

1 reference

Europe PubMed Central

PMC publication ID

22 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

22 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

22 September 2017

ResearchGate publication ID

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