(Q40631541)

22 September 2017

Cdx1 inhibits the proliferation of human colon cancer cells by reducing cyclin D1 gene expression (English)

1 reference

22 September 2017

1 reference

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206770

14 March 2024

author name string

John Lynch

1

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22 September 2017

Matthew Keller

2

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22 September 2017

Rong-Jun Guo

3

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22 September 2017

Donald Yang

4

1 reference

22 September 2017

Peter Traber

5

1 reference

22 September 2017

language of work or name

English

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publication date

1 September 2003

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22 September 2017

25 September 2003

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14508520

full work available at URL

14 March 2024

https://www.nature.com/articles/1206770.pdf

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Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14508520

https://www.nature.com/articles/1206770.pdf

14 March 2024

file format

Portable Document Format

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206770

https://www.nature.com/articles/1206770

14 March 2024

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206770

14 March 2024

1 reference

22 September 2017

22

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22 September 2017

6395-6407

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22 September 2017

41

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1206770

22 September 2017

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cites work

Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206770

Increased expression of cyclin D1 is an early event in multistage colorectal carcinogenesis.

21 January 2018

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Ectopic expression of homeodomain protein CDX2 in intestinal metaplasia and carcinomas of the stomach.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206770

Hepatocyte nuclear factor-1 alpha, GATA-4, and caudal related homeodomain protein Cdx2 interact functionally to modulate intestinal gene transcription. Implication for the developmental regulation of the sucrase-isomaltase gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206770

Stem cells and the regulation of proliferation, differentiation and patterning in the intestinal epithelium: emerging insights from gene expression patterns, transgenic and gene ablation studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206770

The genetic basis of colorectal cancer: insights into critical pathways of tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206770

Expression of the gut-enriched Krüppel-like factor (Krüppel-like factor 4) gene in the human colon cancer cell line RKO is dependent on CDX2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206770

Cyclin D1 and human neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206770

The Cdx-1 and Cdx-2 homeobox genes in the intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206770

S and G2 phase roles for Cdk2 revealed by inducible expression of a dominant-negative mutant in human cells

21 January 2018

1 reference

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Control of endodermal endocrine development by Hes-1

21 January 2018

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The mesenchymal winged helix transcription factor Fkh6 is required for the control of gastrointestinal proliferation and differentiation

21 January 2018

1 reference

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Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206770

Key role of the Cdx2 homeobox gene in extracellular matrix-mediated intestinal cell differentiation

21 January 2018

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21 January 2018

1 reference

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Expression of the Cdx1 and Cdx2 homeotic genes leads to reduced malignancy in colon cancer-derived cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206770

The basic helix-loop-helix protein BETA2 interacts with p300 to coordinate differentiation of secretin-expressing enteroendocrine cells

21 January 2018

1 reference

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Assay for activity of mammalian cyclin D-dependent kinases CDK4 and CDK6.

21 January 2018

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A model for p53-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206770

Phosphorylation of the serine 60 residue within the Cdx2 activation domain mediates its transactivation capacity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206770

The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway

21 January 2018

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CDX1 protein expression in normal, metaplastic, and neoplastic human alimentary tract epithelium

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206770

Cdx1 and cdx2 expression during intestinal development

21 January 2018

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Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the CDK-inhibitor p21WAF1/CiP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206770

Cdx1 promotes differentiation in a rat intestinal epithelial cell line.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206770

Homeobox gene Cdx1 regulates Ras, Rho and PI3 kinase pathways leading to transformation and tumorigenesis of intestinal epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206770

A homeodomain protein related to caudal regulates intestine-specific gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206770

An intestine-specific homeobox gene regulates proliferation and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206770

DNA methylation down-regulates CDX1 gene expression in colorectal cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206770

Intestinal-enriched Krüppel-like factor (Krüppel-like factor 5) is a positive regulator of cellular proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206770

Comparison of intestinal phospholipase A/lysophospholipase and sucrase-isomaltase genes suggest a common structure for enterocyte-specific promoters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206770

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206770

The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

21 January 2018

1 reference

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Requirement of Math1 for secretory cell lineage commitment in the mouse intestine

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206770

p16(INK4a) expression begins early in human colon neoplasia and correlates inversely with markers of cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206770

7 January 2021

GATA family transcription factors activate lactase gene promoter in intestinal Caco-2 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206770

7 January 2021

Differential activation of intestinal gene promoters: functional interactions between GATA-5 and HNF-1 alpha.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206770

7 January 2021

Downregulation of the colon tumour-suppressor homeobox gene Cdx-2 by oncogenic ras

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206770

7 January 2021

Regulation of mammalian cyclin-dependent kinase 2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206770

7 January 2021

The murine Cdx1 gene product localises to the proliferative compartment in the developing and regenerating intestinal epithelium

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206770

7 January 2021

Induction of tissue transglutaminase expression by propionate and n-butyrate in colon cancer cell lines

2

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206770

Colon carbonic anhydrase 1: transactivation of gene expression by the homeodomain protein Cdx2.

14 March 2024

12

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206770

The genetic pathogenesis of colorectal cancer

14 March 2024

24

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206770

14 March 2024

Identifiers

1 reference

Dimensions Publication ID

22 September 2017

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1 reference