(Q40632812)

22 September 2017

title

Presenilin-1 is indirectly implicated in Notch1 cleavage (English)

1 reference

22 September 2017

main subject

cell surface receptor

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14502086

12 March 2024

4

Sébastien S. Hébert

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14502086

12 March 2024

5

Madeleine Carreau

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14502086

12 March 2024

author name string

Chantal Godin

1

1 reference

22 September 2017

Annie Auclair

2

1 reference

22 September 2017

Mélissa Ferland

3

1 reference

22 September 2017

Georges Lévesque

6

1 reference

22 September 2017

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14502086

12 March 2024

publication date

1 August 2003

1 reference

22 September 2017

26 August 2003

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14502086

full work available at URL

12 March 2024

http://journals.lww.com/00001756-200308260-00014

1 reference

https://api.crossref.org/works/10.1097/00001756-200308260-00014

12 March 2024

1 reference

22 September 2017

volume

14

1 reference

22 September 2017

issue

12

1 reference

22 September 2017

page(s)

1613-1616

1 reference

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

22 September 2017

cites work

1

1 reference

https://api.crossref.org/works/10.1097/00001756-200308260-00014

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

12 March 2024

2

1 reference

https://api.crossref.org/works/10.1097/00001756-200308260-00014

Presenilins interact with armadillo proteins including neural-specific plakophilin-related protein and beta-catenin

12 March 2024

3

1 reference

https://api.crossref.org/works/10.1097/00001756-200308260-00014

Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing

12 March 2024

4

1 reference

https://api.crossref.org/works/10.1097/00001756-200308260-00014

aph-1 and pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation

12 March 2024

5

1 reference

https://api.crossref.org/works/10.1097/00001756-200308260-00014

Skeletal and CNS defects in Presenilin-1-deficient mice

12 March 2024

6

1 reference

https://api.crossref.org/works/10.1097/00001756-200308260-00014

Notch1 and amyloid precursor protein are competitive substrates for presenilin1-dependent gamma-secretase cleavage

12 March 2024

7

1 reference

https://api.crossref.org/works/10.1097/00001756-200308260-00014

The Notch1 receptor is cleaved constitutively by a furin-like convertase

12 March 2024

8

1 reference

https://api.crossref.org/works/10.1097/00001756-200308260-00014

A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE

12 March 2024

9

1 reference

https://api.crossref.org/works/10.1097/00001756-200308260-00014

A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain

12 March 2024

10

1 reference

https://api.crossref.org/works/10.1097/00001756-200308260-00014

The Notch-Hes pathway in mammalian neural development

12 March 2024

11

1 reference

https://api.crossref.org/works/10.1097/00001756-200308260-00014

Nicastrin is required for gamma-secretase cleavage of the Drosophila Notch receptor

12 March 2024

12

1 reference

https://api.crossref.org/works/10.1097/00001756-200308260-00014

Evidence for a physical interaction between presenilin and Notch

12 March 2024

13

1 reference

https://api.crossref.org/works/10.1097/00001756-200308260-00014

Dimerization of presenilin-1 in vivo: suggestion of novel regulatory mechanisms leading to higher order complexes

12 March 2024

14

1 reference

https://api.crossref.org/works/10.1097/00001756-200308260-00014

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

12 March 2024

15

1 reference

https://api.crossref.org/works/10.1097/00001756-200308260-00014

Nicastrin binds to membrane-tethered Notch

12 March 2024

16

1 reference

https://api.crossref.org/works/10.1097/00001756-200308260-00014

PEN-2 and APH-1 coordinately regulate proteolytic processing of presenilin 1.

12 March 2024

17

1 reference

https://api.crossref.org/works/10.1097/00001756-200308260-00014

Notch receptor cleavage depends on but is not directly executed by presenilins

12 March 2024

18

1 reference

https://api.crossref.org/works/10.1097/00001756-200308260-00014

Endogenous beta-amyloid production in presenilin-deficient embryonic mouse fibroblasts

12 March 2024

19

1 reference

https://api.crossref.org/works/10.1097/00001756-200308260-00014

Cell-free generation of the notch1 intracellular domain (NICD) and APP-CTfgamma: evidence for distinct intramembranous "gamma-secretase" activities

12 March 2024

20

1 reference

https://api.crossref.org/works/10.1097/00001756-200308260-00014

Presenilin-dependent gamma-secretase-like intramembrane cleavage of ErbB4.

12 March 2024

21

1 reference

https://api.crossref.org/works/10.1097/00001756-200308260-00014

A presenilin-1/gamma-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions

12 March 2024

22

1 reference

https://api.crossref.org/works/10.1097/00001756-200308260-00014

New protease inhibitors prevent gamma-secretase-mediated production of Abeta40/42 without affecting Notch cleavage

12 March 2024

24

1 reference

https://api.crossref.org/works/10.1097/00001756-200308260-00014

12 March 2024

Identifiers

1 reference

22 September 2017

1 reference