(Q40633547)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14499333%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

title

(R)- and (S)-[11C]verapamil as PET-tracers for measuring P-glycoprotein function: in vitro and in vivo evaluation (English)

1 reference

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19 December 2019

3

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19 December 2019

Ronald Boellaard

6

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19 December 2019

Adriaan A Lammertsma

7

1 reference

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19 December 2019

author name string

G Luurtsema

1

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19 December 2019

C F M Molthoff

2

1 reference

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19 December 2019

J W Smit

4

1 reference

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19 December 2019

H Keizer

5

1 reference

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19 December 2019

E J F Franssen

8

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19 December 2019

publication date

1 October 2003

1 reference

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Nuclear Medicine and Biology

19 December 2019

published in

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19 December 2019

volume

30

1 reference

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19 December 2019

issue

7

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19 December 2019

page(s)

747-751

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Considerations in the use of cerebrospinal fluid pharmacokinetics to predict brain target concentrations in the clinical setting: implications of the barriers between blood and brain.

19 December 2019

cites work

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7 January 2021

The impact of efflux transporters in the brain on the development of drugs for CNS disorders

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7 January 2021

Progress in understanding the structure-activity relationships of P-glycoprotein

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7 January 2021

beta-Amyloid efflux mediated by p-glycoprotein

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7 January 2021

Deposition of Alzheimer's beta-amyloid is inversely correlated with P-glycoprotein expression in the brains of elderly non-demented humans.

1 reference

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7 January 2021

Complete in vivo reversal of P-glycoprotein pump function in the blood-brain barrier visualized with positron emission tomography

1 reference

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7 January 2021

Synthesis and evaluation of radiolabeled antagonists for imaging of beta-adrenoceptors in the brain with PET.

1 reference

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7 January 2021

Copper bis(diphosphine) complexes: radiopharmaceuticals for the detection of multi-drug resistance in tumours by PET.

1 reference

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7 January 2021

Novel gallium(III) complexes transported by MDR1 P-glycoprotein: potential PET imaging agents for probing P-glycoprotein-mediated transport activity in vivo

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7 January 2021

Identification of P450 enzymes involved in metabolism of verapamil in humans

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7 January 2021

Simultaneous analysis of verapamil and norverapamil enantiomers in human plasma by high-performance liquid chromatography

1 reference

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7 January 2021

Effects of d,l-verapamil on atrioventricular conduction in relation to its stereoselective first-pass metabolism

1 reference

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7 January 2021

Stereoselective first-pass metabolism of highly cleared drugs: studies of the bioavailability of L- and D-verapamil examined with a stable isotope technique

1 reference

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7 January 2021

Enantioselective kinetics of verapamil and norverapamil in isolated perfused rat livers

1 reference

https://api.crossref.org/works/10.1016%2FS0969-8051%2803%2900078-7

7 January 2021

Enantioselective distribution of verapamil and norverapamil into human and rat erythrocytes: the role of plasma protein binding

1 reference

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7 January 2021

Effect of verapamil enantiomers and metabolites on cardiac K+ channels expressed in Xenopus oocytes.

1 reference

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7 January 2021

Verapamil stereoisomerism: enantiomeric ratios in plasma dependent on peak concentrations, oral input rate, or both.

1 reference

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7 January 2021

R-(+)-verapamil, S-(-)-verapamil, and racemic verapamil inhibit human retinal pigment epithelial cell contraction

1 reference

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7 January 2021

Pharmacokinetics of (+)-, (-)- and (+/-)-verapamil after intravenous administration

1 reference

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7 January 2021

Pharmacokinetics of the enantiomers of verapamil after intravenous and oral administration of racemic verapamil in a rat model

1 reference

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7 January 2021

Fully automated high yield synthesis of (R)- and (S)-[11C]verapamil for measuring P-glycoprotein function with positron emission tomography

1 reference

https://api.crossref.org/works/10.1016%2FS0969-8051%2803%2900078-7

7 January 2021

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0969-8051%2803%2900078-7

7 January 2021

Pharmacokinetics and biodistribution of a new anti-episialin monoclonal antibody 139H2 in ovarian-cancer-bearing nude mice

1 reference

https://api.crossref.org/works/10.1016%2FS0969-8051%2803%2900078-7

7 January 2021

Characterization of a single LSO crystal layer high resolution research tomograph

1 reference

https://api.crossref.org/works/10.1016%2FS0969-8051%2803%2900078-7

7 January 2021

P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0969-8051%2803%2900078-7

7 January 2021

10.1016/S0969-8051(03)00078-7

Identifiers

DOI

1 reference

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19 December 2019

1 reference