(Q40640705)

22 September 2017

title

Vanadate and rapamycin synergistically enhance insulin-stimulated glucose uptake (English)

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22 September 2017

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Jason C O'Connor

1

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22 September 2017

Gregory G Freund

series ordinal

2

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22 September 2017

language of work or name

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1 June 2003

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22 September 2017

number of pages

9

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based on heuristic

inferred from page(s)

published in

Metabolism

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22 September 2017

volume

52

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22 September 2017

issue

6

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22 September 2017

page(s)

666-674

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Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance

22 September 2017

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Pleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1

7 January 2021

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Characterization of two 85 kd proteins that associate with receptor tyrosine kinases, middle-T/pp60c-src complexes, and PI3-kinase

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Protein tyrosine phosphatase-1B in diabetes

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Down-regulation of Insulin Signaling by Protein-tyrosine Phosphatase 1B Is Mediated by an N-terminal Binding Region

7 January 2021

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Tyrosine dephosphorylation and deactivation of insulin receptor substrate-1 by protein-tyrosine phosphatase 1B. Possible facilitation by the formation of a ternary complex with the Grb2 adaptor protein

7 January 2021

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The transmembrane protein tyrosine phosphatase alpha dephosphorylates the insulin receptor in intact cells

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The COOH-terminal tyrosine phosphorylation sites on IRS-1 bind SHP-2 and negatively regulate insulin signaling

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Increased abundance of the receptor-type protein-tyrosine phosphatase LAR accounts for the elevated insulin receptor dephosphorylating activity in adipose tissue of obese human subjects

7 January 2021

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PTEN inhibits insulin-stimulated MEK/MAPK activation and cell growth by blocking IRS-1 phosphorylation and IRS-1/Grb-2/Sos complex formation in a breast cancer model

7 January 2021

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7 January 2021

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7 January 2021

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Insulin in combination with vanadate stimulates glucose transport in isolated cardiomyocytes from obese Zucker rats

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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A rapamycin-sensitive pathway down-regulates insulin signaling via phosphorylation and proteasomal degradation of insulin receptor substrate-1.

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Insulin-like actions of vanadate are mediated in an insulin-receptor-independent manner via non-receptor protein tyrosine kinases and protein phosphotyrosine phosphatases

7 January 2021

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Effect of vanadate on elevated blood glucose and depressed cardiac performance of diabetic rats

7 January 2021

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A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1.

7 January 2021

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Differential effects of phosphatidylinositol 3-kinase inhibition on intracellular signals regulating GLUT4 translocation and glucose transport

7 January 2021

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7 January 2021

Vanadium and diabetes

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Enhanced sensitivity of insulin-resistant adipocytes to vanadate is associated with oxidative stress and decreased reduction of vanadate (+5) to vanadyl (+4).

7 January 2021

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7 January 2021

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10.1016/S0026-0495(03)00026-X

7 January 2021

Identifiers

DOI

1 reference

22 September 2017

1 reference