(Q40641201)

22 September 2017

title

2-Methylene-19-nor-(20S)-1,25-dihydroxyvitamin D3 potently stimulates gene-specific DNA binding of the vitamin D receptor in osteoblasts (English)

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22 September 2017

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5

Hector F DeLuca

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22 September 2017

Hironori Yamamoto

1

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22 September 2017

Nirupama K Shevde

2

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22 September 2017

Anjali Warrier

3

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22 September 2017

Lori A Plum

4

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22 September 2017

J Wesley Pike

6

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22 September 2017

language of work or name

English

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publication date

9 June 2003

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Journal of Biological Chemistry

22 September 2017

published in

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22 September 2017

volume

278

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22 September 2017

issue

34

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22 September 2017

page(s)

31756-31765

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The nuclear vitamin D receptor: biological and molecular regulatory properties revealed.

22 September 2017

cites work

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Point mutations in the human vitamin D receptor gene associated with hypocalcemic rickets

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Targeted ablation of the vitamin D receptor: an animal model of vitamin D-dependent rickets type II with alopecia

21 January 2018

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Distinct retinoid X receptor activation function-2 residues mediate transactivation in homodimeric and vitamin D receptor heterodimeric contexts

21 January 2018

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Distinct conformational changes induced by 20-epi analogues of 1 alpha,25-dihydroxyvitamin D3 are associated with enhanced activation of the vitamin D receptor

21 January 2018

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Molecular basis of the selective activity of vitamin D analogues

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The crystal structure of the nuclear receptor for vitamin D bound to its natural ligand

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Crystal structures of the vitamin D receptor complexed to superagonist 20-epi ligands

21 January 2018

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New 1alpha,25-dihydroxy-19-norvitamin D3 compounds of high biological activity: synthesis and biological evaluation of 2-hydroxymethyl, 2-methyl, and 2-methylene analogues

21 January 2018

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A potent analog of 1alpha,25-dihydroxyvitamin D3 selectively induces bone formation

21 January 2018

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The roles of osteoprotegerin and osteoprotegerin ligand in the paracrine regulation of bone resorption.

21 January 2018

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A chimeric form of osteoprotegerin inhibits hypercalcemia and bone resorption induced by IL-1beta, TNF-alpha, PTH, PTHrP, and 1, 25(OH)2D3.

21 January 2018

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Retinoid X receptor (RXR) ligands activate the human 25-hydroxyvitamin D3-24-hydroxylase promoter via RXR heterodimer binding to two vitamin D-responsive elements and elicit additive effects with 1,25-dihydroxyvitamin D3.

21 January 2018

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Dissection of the LXXLL nuclear receptor-coactivator interaction motif using combinatorial peptide libraries: discovery of peptide antagonists of estrogen receptors alpha and beta

21 January 2018

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Inhibition of 1,25-dihydroxyvitamin D3-dependent transcription by synthetic LXXLL peptide antagonists that target the activation domains of the vitamin D and retinoid X receptors

21 January 2018

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Estrogens suppress RANK ligand-induced osteoclast differentiation via a stromal cell independent mechanism involving c-Jun repression

21 January 2018

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Identification of unknown target genes of human transcription factors using chromatin immunoprecipitation

21 January 2018

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Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription

21 January 2018

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21 January 2018

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A signature motif in transcriptional co-activators mediates binding to nuclear receptors

21 January 2018

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A new active vitamin D analog, ED-71, causes increase in bone mass with preferential effects on bone in osteoporotic patients

21 January 2018

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2 alpha-(3-hydroxypropyl)- and 2 alpha-(3-hydroxypropoxy)-1 alpha,25-dihydroxyvitamin D3 accessible to vitamin D receptor mutant related to hereditary vitamin D-resistant rickets

21 January 2018

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The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen

21 January 2018

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Proteasome-dependent degradation of the human estrogen receptor

21 January 2018

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A novel androgen receptor mutant, A748T, exhibits hormone concentration-dependent defects in nuclear accumulation and activity despite normal hormone-binding affinity

21 January 2018

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Calcipotriol (MC 903): pharmacokinetics in rats and biological activities of metabolites. A comparative study with 1,25(OH)2D3.

21 January 2018

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Role of MAP kinases in the 1,25-dihydroxyvitamin D3-induced transactivation of the rat cytochrome P450C24 (CYP24) promoter. Specific functions for ERK1/ERK2 and ERK5

21 January 2018

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21 January 2018

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Phosphorylation of steroid receptor coactivator-1. Identification of the phosphorylation sites and phosphorylation through the mitogen-activated protein kinase pathway.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M304737200

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22 September 2017

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