(Q40646939)

22 September 2017

title

Cbl-mediated ubiquitinylation is required for lysosomal sorting of epidermal growth factor receptor but is dispensable for endocytosis (English)

1 reference

22 September 2017

Cbl-mediated Ubiquitinylation Is Required for Lysosomal Sorting of Epidermal Growth Factor Receptor but Is Dispensable for Endocytosis (English)

1 reference

https://api.crossref.org/works/10.1074/JBC.M304474200

3 January 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M304474200

3 January 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M304474200

3 January 2024

15

Mayumi Naramura

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12754251

3 January 2024

author name string

Lei Duan

1

1 reference

22 September 2017

Yuko Miura

2

1 reference

22 September 2017

Manjari Dimri

3

1 reference

22 September 2017

Biswanath Majumder

4

1 reference

22 September 2017

Amiya Ghosh

7

1 reference

22 September 2017

Norvin Fernandes

8

1 reference

22 September 2017

Pengcheng Zhou

9

1 reference

22 September 2017

Karen Mullane-Robinson

10

1 reference

22 September 2017

Navin Rao

11

1 reference

22 September 2017

Stephen Donoghue

12

1 reference

22 September 2017

David Bowtell

14

1 reference

22 September 2017

Hua Gu

16

1 reference

22 September 2017

Vimla Band

17

1 reference

22 September 2017

Hamid Band

18

1 reference

22 September 2017

Ingrid L. Dodge

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12754251

3 January 2024

Alagarsamy L. Reddi

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12754251

3 January 2024

Rick A. Rogers

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12754251

3 January 2024

language of work or name

English

0 references

publication date

18 May 2003

1 reference

full work available at URL

22 September 2017

http://www.jbc.org/article/S0021925820843932/pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12754251

https://api.elsevier.com/content/article/PII:S0021925820843932?httpAccept=text/xml

3 January 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M304474200

https://api.elsevier.com/content/article/PII:S0021925820843932?httpAccept=text/plain

3 January 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M304474200

https://syndication.highwire.org/content/doi/10.1074/jbc.M304474200

3 January 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M304474200

Journal of Biological Chemistry

3 January 2024

published in

1 reference

22 September 2017

volume

278

1 reference

22 September 2017

issue

31

1 reference

22 September 2017

page(s)

28950-28960

1 reference

Control of EGF receptor signaling by clathrin-mediated endocytosis.

22 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

Down-regulation of the epidermal growth factor receptor in KB cells is due to receptor internalization and subsequent degradation in lysosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

Multivesicular endosomes containing internalized EGF-EGF receptor complexes mature and then fuse directly with lysosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

Regulation of epidermal growth factor receptor signaling by endocytosis and intracellular trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

Alternative intracellular routing of ErbB receptors may determine signaling potency

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

Differential endocytic routing of homo- and hetero-dimeric ErbB tyrosine kinases confers signaling superiority to receptor heterodimers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

ErbB-2 amplification inhibits down-regulation and induces constitutive activation of both ErbB-2 and epidermal growth factor receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

Molecular mechanisms underlying ErbB2/HER2 action in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

Molecular mechanisms underlying endocytosis and sorting of ErbB receptor tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

Cbl: many adaptations to regulate protein tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

Tyrosine phosphorylation of Cbl upon epidermal growth factor (EGF) stimulation and its association with EGF receptor and downstream signaling proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

RING finger mutations that abolish c-Cbl-directed polyubiquitination and downregulation of the EGF receptor are insufficient for cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

Ubiquitination and proteasomal activity is required for transport of the EGF receptor to inner membranes of multivesicular bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

Ubiquitination of a yeast plasma membrane receptor signals its ligand-stimulated endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

Multiple roles for Rsp5p-dependent ubiquitination at the internalization step of endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

Identification of a novel ubiquitin conjugation motif, required for ligand-induced internalization of the growth hormone receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

Cbl-directed monoubiquitination of CIN85 is involved in regulation of ligand-induced degradation of EGF receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

The endophilin-CIN85-Cbl complex mediates ligand-dependent downregulation of c-Met

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

Grb2 regulates internalization of EGF receptors through clathrin-coated pits

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

Protein regulation by monoubiquitin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

The non-receptor tyrosine kinase Syk is a target of Cbl-mediated ubiquitylation upon B-cell receptor stimulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

Growth hormone-induced signal tranduction depends on an intact ubiquitin system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

Tissue hyperplasia and enhanced T-cell signalling via ZAP-70 in c-Cbl-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

Altered thymic positive selection and intracellular signals in Cbl-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

High frequency of SV40 transformation of mouse cell line 3T3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

The Cbl proto-oncogene product negatively regulates the Src-family tyrosine kinase Fyn by enhancing its degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

Negative regulation of Lck by Cbl ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

Phosphotyrosine binding domain-dependent upregulation of the platelet-derived growth factor receptor alpha signaling cascade by transforming mutants of Cbl: implications for Cbl's function and oncogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

Cbl-mediated negative regulation of the Syk tyrosine kinase. A critical role for Cbl phosphotyrosine-binding domain binding to Syk phosphotyrosine 323

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

Cbl-b-dependent coordinated degradation of the epidermal growth factor receptor signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

Mammalian class E vps proteins recognize ubiquitin and act in the removal of endosomal protein-ubiquitin conjugates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

Ligand-induced ubiquitination of the epidermal growth factor receptor involves the interaction of the c-Cbl RING finger and UbcH7

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

Endocytosis of epidermal growth factor receptor regulated by Grb2-mediated recruitment of the Rab5 GTPase-activating protein RN-tre

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

Epsins and Vps27p/Hrs contain ubiquitin-binding domains that function in receptor endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

Hrs regulates endosome membrane invagination and tyrosine kinase receptor signaling in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

A leucine-based determinant in the epidermal growth factor receptor juxtamembrane domain is required for the efficient transport of ligand-receptor complexes to lysosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

Ligand-induced endocytosis of epidermal growth factor receptors that are defective in binding adaptor proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

Receptor downregulation and multivesicular-body sorting

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304474200

The evolutionarily conserved N-terminal region of Cbl is sufficient to enhance down-regulation of the epidermal growth factor receptor

21 January 2018

17

1 reference

https://api.crossref.org/works/10.1074/JBC.M304474200

c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor

3 January 2024

42

1 reference

https://api.crossref.org/works/10.1074/JBC.M304474200

cbl-b inhibits EGF-receptor-induced apoptosis by enhancing ubiquitination and degradation of activated receptors

3 January 2024

43

1 reference

https://api.crossref.org/works/10.1074/JBC.M304474200

3 January 2024

Identifiers

1 reference

22 September 2017

1 reference