(Q40651711)

English

Infectious delivery of a 135-kb LDLR genomic locus leads to regulated complementation of low-density lipoprotein receptor deficiency in human cells.

scientific article published on May 2003

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scholarly article

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3 November 2019

Infectious delivery of a 135-kb LDLR genomic locus leads to regulated complementation of low-density lipoprotein receptor deficiency in human cells (English)

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Europe PubMed Central

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3 November 2019

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Richard Wade-Martins

1

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3 November 2019

author name string

Yoshinaga Saeki

2

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3 November 2019

E Antonio Chiocca

3

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3 November 2019

publication date

1 May 2003

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3 November 2019

Molecular Therapy

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12718903%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

7

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3 November 2019

5 Pt 1

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3 November 2019

604-612

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12718903%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

Initial sequencing and analysis of the human genome

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The Sequence of the Human Genome

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An infectious transfer and expression system for genomic DNA loci in human and mouse cells

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Infectious delivery of 120-kilobase genomic DNA by an epstein-barr virus amplicon vector

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Regulation of the activity of the low density lipoprotein receptor in human fibroblasts

1 reference

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cDNA cloning of the bovine low density lipoprotein receptor: feedback regulation of a receptor mRNA

1 reference

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42 bp element from LDL receptor gene confers end-product repression by sterols when inserted into viral TK promoter

1 reference

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Improved helper virus-free packaging system for HSV amplicon vectors using an ICP27-deleted, oversized HSV-1 DNA in a bacterial artificial chromosome

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Isolation of Chinese hamster cell mutants defective in the receptor-mediated endocytosis of low density lipoprotein

1 reference

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Entry of alphaherpesviruses mediated by poliovirus receptor-related protein 1 and poliovirus receptor

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Sequences adjacent to oriP improve the persistence of Epstein-Barr virus-based episomes in B cells

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Stable replication of plasmids derived from Epstein-Barr virus in various mammalian cells

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Isolation of human sequences that replicate autonomously in human cells

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Epstein-Barr virus-based vectors that replicate in rodent cells

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Correction of the genetic defect in hepatocytes from the Watanabe heritable hyperlipidemic rabbit.

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Efficient expression of retroviral vector-transduced human low density lipoprotein (LDL) receptor in LDL receptor-deficient rabbit fibroblasts in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900060-1

7 January 2021

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Adenovirus-mediated correction of the genetic defect in hepatocytes from patients with familial hypercholesterolemia

1 reference

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7 January 2021

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Adenovirus-mediated transfer of low density lipoprotein receptor gene acutely accelerates cholesterol clearance in normal mice

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900060-1

7 January 2021

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Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery

1 reference

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7 January 2021

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In vivo gene therapy for hyperlipidemia: phenotypic correction in Watanabe rabbits by hepatic delivery of the rabbit LDL receptor gene

1 reference

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7 January 2021

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Effective treatment of familial hypercholesterolaemia in the mouse model using adenovirus-mediated transfer of the VLDL receptor gene

1 reference

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7 January 2021

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Prolonged correction of hyperlipidemia in mice with familial hypercholesterolemia using an adeno-associated viral vector expressing very-low-density lipoprotein receptor.

1 reference

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7 January 2021

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Long-Term Improvement of Hypercholesterolemia After Ex Vivo Gene Therapy in LDLR-Deficient Rabbits

1 reference

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Successful ex vivo gene therapy directed to liver in a patient with familial hypercholesterolaemia

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A pilot study of ex vivo gene therapy for homozygous familial hypercholesterolaemia

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7 January 2021

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Nonphysiological overexpression of low-density lipoprotein receptors causes pathological intracellular lipid accumulation and the formation of cholesterol and cholesteryl ester crystals in vitro

1 reference

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Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus

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The DNA sequence of human chromosome 21

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Green fluorescent protein as a reporter for retrovirus and helper virus-free HSV-1 amplicon vector-mediated gene transfer into neural cells in culture and in vivo.

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Versatile insertion plasmids for targeted genome manipulations in bacteria: isolation, deletion, and rescue of the pathogenicity island LEE of the Escherichia coli O157:H7 genome

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A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes

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19 Receptor-mediated endocytosis of low-density lipoprotein in cultured cells

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Identifiers

10.1016/S1525-0016(03)00060-1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12718903%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12718903%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

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