(Q40653432)

22 September 2017

RAD51 is involved in repair of damage associated with DNA replication in mammalian cells (English)

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22 September 2017

6

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22 September 2017

Cecilia Lundin

1

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22 September 2017

Niklas Schultz

2

1 reference

22 September 2017

Catherine Arnaudeau

3

1 reference

22 September 2017

Atul Mohindra

4

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22 September 2017

Lasse Tengbjerg Hansen

5

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22 September 2017

language of work or name

English

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publication date

1 May 2003

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Journal of Molecular Biology

22 September 2017

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22 September 2017

328

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22 September 2017

521-535

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22 September 2017

3

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Genome maintenance mechanisms for preventing cancer

22 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Chromosomal stability and the DNA double-stranded break connection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Role of the human RAD51 protein in homologous recombination and double-stranded-break repair.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Human Rad51 protein promotes ATP-dependent homologous pairing and strand transfer reactions in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Targeted disruption of the Rad51 gene leads to lethality in embryonic mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Rad51-deficient vertebrate cells accumulate chromosomal breaks prior to cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Rescue of arrested replication forks by homologous recombination

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Characterization of homologous recombination induced by replication inhibition in mammalian cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Different roles for nonhomologous end joining and homologous recombination following replication arrest in mammalian cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Elevated recombination in immortal human cells is mediated by HsRAD51 recombinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

p53 splice acceptor site mutation and increased HsRAD51 protein expression in Bloom's syndrome GM1492 fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Increase of spontaneous intrachromosomal homologous recombination in mammalian cells expressing a mutant p53 protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Inactivation of p53 results in high rates of homologous recombination

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

p53 is linked directly to homologous recombination processes via RAD51/RecA protein interaction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

A transactivation-deficient mouse model provides insights into Trp53 regulation and function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Functional proteomics of transforming growth factor-beta1-stimulated Mv1Lu epithelial cells: Rad51 as a target of TGFbeta1-dependent regulation of DNA repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Association of BRCA1 with Rad51 in mitotic and meiotic cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Brca2 is required for embryonic cellular proliferation in the mouse

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Involvement of Brca2 in DNA repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Role of BRCA2 in control of the RAD51 recombination and DNA repair protein.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

RAD51 interacts with the evolutionarily conserved BRC motifs in the human breast cancer susceptibility gene brca2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Expression of BRC repeats in breast cancer cells disrupts the BRCA2-Rad51 complex and leads to radiation hypersensitivity and loss of G(2)/M checkpoint control

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Brca2 (XRCC11) deficiency results in radioresistant DNA synthesis and a higher frequency of spontaneous deletions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

BRCA2 is required for homology-directed repair of chromosomal breaks

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Deficiency in BRCA2 leads to increase in non-conservative homologous recombination.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Cancer susceptibility and the functions of BRCA1 and BRCA2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Identification of Rad51 alteration in patients with bilateral breast cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Detection of loss of heterozygosity at RAD51, RAD52, RAD54 and BRCA1 and BRCA2 loci in breast cancer: pathological correlations.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

DNA repair and recombination factor Rad51 is over-expressed in human pancreatic adenocarcinoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Overexpression of Rad51 protein stimulates homologous recombination and increases resistance of mammalian cells to ionizing radiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

The RAD51 protein supports homologous recombination by an exchange mechanism in mammalian cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Gene targeting is enhanced in human cells overexpressing hRAD51.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Characterization of mammalian RAD51 double strand break repair using non-lethal dominant-negative forms.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Overexpression of human RAD51 and RAD52 reduces double-strand break-induced homologous recombination in mammalian cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Role for caspase-mediated cleavage of Rad51 in induction of apoptosis by DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

A partial hprt gene duplication generated by non-homologous recombination in V79 Chinese hamster cells is eliminated by homologous recombination

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Reduction of Ribonucleotides

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

International Commission for Protection Against Environmental Mutagens and Carcinogens. Mutagenicity and carcinogenicity of topoisomerase-interactive agents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Eucaryotic DNA: organization of the genome for replication

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Localization to chromosome 7q36.1 of the human XRCC2 gene, determining sensitivity to DNA-damaging agents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

The isolation and genetic analysis of V79-derived etoposide sensitive Chinese hamster cell mutants: two new complementation groups of etoposide sensitive mutants.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Correction of chromosomal instability and sensitivity to diverse mutagens by a cloned cDNA of the XRCC3 DNA repair gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Absence of p350 subunit of DNA-activated protein kinase from a radiosensitive human cell line

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Effects of HsRad51 overexpression on cell proliferation, cell cycle progression, and apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Inhibition of DNA synthesis is a potent mechanism by which cytostatic drugs induce homologous recombination in mammalian cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Circular DNA of 3T6R50 double minute chromosomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Estimation of circular DNA size using gamma-irradiation and pulsed-field gel electrophoresis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Measurement of DNA Double-strand Breaks in CHO Cells at Various Stages of the Cell Cycle Using Pulsed Field Gel Electrophoresis: Calibration by Means of125I Decay

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Topoisomerase II can unlink replicating DNA by precatenane removal

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

BCR/ABL regulates mammalian RecA homologs, resulting in drug resistance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

A model for replication repair in mammalian cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Positive torsional strain causes the formation of a four-way junction at replication forks

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Holliday junctions accumulate in replication mutants via a RecA homolog-independent mechanism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Characterization of mutants involving partial exon duplications in the hprt gene of Chinese hamster V79 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

XRCC3 promotes homology-directed repair of DNA damage in mammalian cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

XRCC3 is required for efficient repair of chromosome breaks by homologous recombination

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

10.1016/S0022-2836(03)00313-9

7 January 2021

Identifiers

DOI

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22 September 2017

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