(Q40653906)

22 September 2017

Induced stabilization of IkappaBalpha can facilitate its re-synthesis and prevent sequential degradation (English)

1 reference

22 September 2017

Induced stabilization of IκBα can facilitate its re‐synthesis and prevent sequential degradation (English)

1 reference

25 December 2023

1 reference

25 December 2023

1 reference

25 December 2023

author name string

Derek Haspeslagh

2

1 reference

22 September 2017

Charles Giardina

3

1 reference

22 September 2017

Robert F. Place

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12704657

25 December 2023

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12704657

25 December 2023

publication date

1 June 2003

1 reference

full work available at URL

22 September 2017

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fjcp.10262

1 reference

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jcp.10262

25 December 2023

1 reference

Journal of Cellular Physiology

25 December 2023

published in

1 reference

22 September 2017

195

1 reference

22 September 2017

470-478

1 reference

22 September 2017

3

1 reference

Function and activation of NF-kappa B in the immune system

22 September 2017

1 reference

Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradation

21 January 2018

1 reference

I kappa B/MAD-3 masks the nuclear localization signal of NF-kappa B p65 and requires the transactivation domain to inhibit NF-kappa B p65 DNA binding

21 January 2018

1 reference

Phosphorylation of IkappaBalpha in the C-terminal PEST domain by casein kinase II affects intrinsic protein stability

21 January 2018

1 reference

Inducible degradation of I kappa B alpha in vitro and in vivo requires the acidic C-terminal domain of the protein

21 January 2018

1 reference

Functional characterization of the NF-kappa B p65 transcriptional activator and an alternatively spliced derivative

21 January 2018

1 reference

Crucial role of the amino-terminal tyrosine residue 42 and the carboxyl-terminal PEST domain of I kappa B alpha in NF-kappa B activation by an oxidative stress

21 January 2018

1 reference

Constitutive phosphorylation of IkappaBalpha by casein kinase II occurs preferentially at serine 293: requirement for degradation of free IkappaBalpha

21 January 2018

1 reference

Phosphorylation by the protein kinase CK2 promotes calpain-mediated degradation of IkappaBalpha

21 January 2018

1 reference

Both amino- and carboxyl-terminal sequences within I kappa B alpha regulate its inducible degradation

21 January 2018

1 reference

Signal-induced degradation of I(kappa)B(alpha): association with NF-kappaB and the PEST sequence in I(kappa)B(alpha) are not required

21 January 2018

1 reference

Cell stress and MKK6b-mediated p38 MAP kinase activation inhibit tumor necrosis factor-induced IkappaB phosphorylation and NF-kappaB activation

21 January 2018

1

1 reference

Pharmacological profile of SB 203580, a selective inhibitor of cytokine suppressive binding protein/p38 kinase, in animal models of arthritis, bone resorption, endotoxin shock and immune function

25 December 2023

2

1 reference

The NF-kappa B and I kappa B proteins: new discoveries and insights

25 December 2023

4

1 reference

The 65-kDa subunit of human NF-kappa B functions as a potent transcriptional activator and a target for v-Rel-mediated repression

25 December 2023

5

1 reference

Constitutive phosphorylation of I kappa B alpha by casein kinase II.

25 December 2023

6

1 reference

The role of the C-terminal domain of I kappa B alpha in protein degradation and stabilization

25 December 2023

7

1 reference

The I kappa B proteins: multifunctional regulators of Rel/NF-kappa B transcription factors

25 December 2023

8

1 reference

I kappa B interacts with the nuclear localization sequences of the subunits of NF-kappa B: a mechanism for cytoplasmic retention

25 December 2023

9

1 reference

Identification of signal-induced IkappaB-alpha kinases in human endothelial cells

25 December 2023

10

1 reference

Effect of the p38 kinase inhibitor, SB 203580, on sephadex induced airway inflammation in the rat

25 December 2023

11

1 reference

Cloning of a mitogen-inducible gene encoding a κB DNA-binding protein with homology to the rel oncogene and to cell-cycle motifs

25 December 2023

12

1 reference

PKC-zeta-associated CK2 participates in the turnover of free IkappaBalpha

25 December 2023

14

1 reference

Mutual regulation of the transcriptional activator NF-kappa B and its inhibitor, I kappa B-alpha

25 December 2023

15

1 reference

Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

25 December 2023

16

1 reference

A subclass of Ras proteins that regulate the degradation of IkappaB

25 December 2023

19

1 reference

Inducible phosphorylation of I kappa B alpha is not sufficient for its dissociation from NF-kappa B and is inhibited by protease inhibitors

25 December 2023

20

1 reference

Activation in vitro of NF-kappa B by phosphorylation of its inhibitor I kappa B

25 December 2023

22

1 reference

Evaluation of human cytokine production and effects of pharmacological agents in a heterologous system in vivo

25 December 2023

24

1 reference

Tumor necrosis factor-alpha-inducible IkappaBalpha proteolysis mediated by cytosolic m-calpain. A mechanism parallel to the ubiquitin-proteasome pathway for nuclear factor-kappab activation

25 December 2023

25

1 reference

Characterization of an immediate-early gene induced in adherent monocytes that encodes IκB-like activity

25 December 2023

26

1 reference

The luminal short-chain fatty acid butyrate modulates NF-kappaB activity in a human colonic epithelial cell line

25 December 2023

27

1 reference

Three NF-kappa B sites in the I kappa B-alpha promoter are required for induction of gene expression by TNF alpha

25 December 2023

28

1 reference

p38 protects human melanoma cells from UV-induced apoptosis through down-regulation of NF-kappaB activity and Fas expression

25 December 2023

29

1 reference

HIV gp120 enhances NO production by cardiac myocytes through p38 MAP kinase-mediated NF-kappaB activation

25 December 2023

30

1 reference

The DNA binding subunit of NF-kappa B is identical to factor KBF1 and homologous to the rel oncogene product

25 December 2023

31

1 reference

p38 MAPK-mediated activation of NF-kappaB by the RhoGEF domain of Bcr.

25 December 2023

32

1 reference

Different mechanisms control signal-induced degradation and basal turnover of the NF-kappaB inhibitor IkappaB alpha in vivo

25 December 2023

33

1 reference

The carboxy-terminus of I kappaB alpha determines susceptibility to degradation by the catalytic core of the proteasome

25 December 2023

34

1 reference

Cloning of the DNA-binding subunit of human nuclear factor kappa B: the level of its mRNA is strongly regulated by phorbol ester or tumor necrosis factor alpha

25 December 2023

36

1 reference

Tumor necrosis factor alpha-induced phosphorylation of I kappa B alpha is a signal for its degradation but not dissociation from NF-kappa B

25 December 2023

37

1 reference

DNA binding and I kappa B inhibition of the cloned p65 subunit of NF-kappa B, a rel-related polypeptide

25 December 2023

38

1 reference

The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B

25 December 2023

39

1 reference

Cytokine-induced stabilization of newly synthesized I(kappa)B-alpha

25 December 2023

40

1 reference

Identification and characterization of an IkappaB kinase

25 December 2023

41

1 reference

Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis

25 December 2023

43

1 reference

Isolation of a rel-related human cDNA that potentially encodes the 65-kD subunit of NF-kappa B

25 December 2023

44

1 reference

Signal-induced degradation of I kappa B alpha requires site-specific ubiquitination

25 December 2023

46

1 reference

The p65 subunit of NF-kappa B regulates I kappa B by two distinct mechanisms

25 December 2023

50

1 reference

The PEST domain of IkappaBalpha is necessary and sufficient for in vitro degradation by mu-calpain

25 December 2023

52

1 reference

NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway

25 December 2023

53

1 reference

Dichotomal role of inhibition of p38 MAPK with SB 203580 in experimental colitis

25 December 2023

55

1 reference

A proteasome inhibitor prevents activation of NF-kappa B and stabilizes a newly phosphorylated form of I kappa B-alpha that is still bound to NF-kappa B

25 December 2023

56

1 reference

Activation of transcription factor NF-kappaB and p38 mitogen-activated protein kinase is mediated by distinct and separate stress effector pathways

25 December 2023

58

1 reference

Inhibition of NF-kappa-B cellular function via specific targeting of the I-kappa-B-ubiquitin ligase

25 December 2023

60

1 reference

p38 Triggers late preconditioning elicited by anisomycin in heart: involvement of NF-kappaB and iNOS.

25 December 2023

61

1 reference

25 December 2023

Identifiers

DOI

10.1002/JCP.10262

1 reference

22 September 2017

1 reference