(Q35594482)

9 August 2017

title

Dichotomal role of inhibition of p38 MAPK with SB 203580 in experimental colitis (English)

1 reference

9 August 2017

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T ten Hove

1

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9 August 2017

B van den Blink

2

1 reference

9 August 2017

I Pronk

3

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9 August 2017

P Drillenburg

4

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9 August 2017

M P Peppelenbosch

5

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9 August 2017

S J H van Deventer

6

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9 August 2017

language of work or name

English

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publication date

1 April 2002

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9 August 2017

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9 August 2017

volume

50

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9 August 2017

issue

4

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9 August 2017

page(s)

507-512

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Activation of p38 mitogen-activated protein kinase in vivo selectively induces apoptosis of CD8(+) but not CD4(+) T cells

9 August 2017

cites work

1 reference

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Anti-interleukin 12 treatment regulates apoptosis of Th1 T cells in experimental colitis in mice.

27 July 2018

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p38 MAPK signalling cascades in inflammatory disease

27 July 2018

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Defective IL-12 production in mitogen-activated protein (MAP) kinase kinase 3 (Mkk3)-deficient mice

27 July 2018

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T cell activation signals up-regulate p38 mitogen-activated protein kinase activity and induce TNF-alpha production in a manner distinct from LPS activation of monocytes.

27 July 2018

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Inflammatory bowel disease: etiology and pathogenesis

27 July 2018

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Interferon-gamma expression by Th1 effector T cells mediated by the p38 MAP kinase signaling pathway

27 July 2018

1 reference

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A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

27 July 2018

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Tumour necrosis factor and inflammatory bowel disease

27 July 2018

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A p38 MAP kinase inhibitor SB203580 inhibits CD28-dependent T cell proliferation and IL-2 production

27 July 2018

1 reference

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Tumour necrosis factor and Crohn's disease

27 July 2018

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T cell proliferation in response to interleukins 2 and 7 requires p38MAP kinase activation.

27 July 2018

1 reference

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Mitogen-activated protein (MAP) kinase regulates production of tumor necrosis factor-alpha and release of arachidonic acid in mast cells. Indications of communication between p38 and p42 MAP kinases

27 July 2018

1 reference

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Pyridinyl imidazole inhibitors of p38 mitogen-activated protein kinase bind in the ATP site

27 July 2018

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Current concepts of the etiology and pathogenesis of ulcerative colitis and Crohn's disease.

27 July 2018

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The p38/RK mitogen-activated protein kinase pathway regulates interleukin-6 synthesis response to tumor necrosis factor

27 July 2018

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Cytokines in intestinal inflammation: pathophysiological and clinical considerations.

27 July 2018

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A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773163

A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773163

A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773163

Current concepts of the pathogenesis of inflammatory bowel disease

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773163

SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773163

Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773163

Phenotypic and functional heterogeneity of CD4+ T cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773163

Inflammatory bowel disease (1)

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773163

p38 MAP kinase mediates bax translocation in nitric oxide-induced apoptosis in neurons

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773163

Evidence of a central role for p38 map kinase induction of tumor necrosis factor alpha in pancreatitis-associated pulmonary injury.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773163

Hapten-induced colitis is associated with colonic patch hypertrophy and T helper cell 2-type responses

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773163

Differential roles of ERK and p38 MAP kinase pathways in positive and negative selection of T lymphocytes.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773163

An interleukin 12-related cytokine is up-regulated in ulcerative colitis but not in Crohn's disease

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773163

Pharmacological profile of SB 203580, a selective inhibitor of cytokine suppressive binding protein/p38 kinase, in animal models of arthritis, bone resorption, endotoxin shock and immune function

26 September 2018

1 reference

12 December 2020

Predominant pathogenic role of tumor necrosis factor in experimental colitis in mice

1 reference

12 December 2020

Pharmacological effects of SB 220025, a selective inhibitor of P38 mitogen-activated protein kinase, in angiogenesis and chronic inflammatory disease models

1 reference

12 December 2020

Role of Interleukin (IL)-2 Receptor β-Chain Subdomains and Shc in p38 Mitogen-activated Protein (MAP) Kinase and p54 MAP Kinase (Stress-activated Protein Kinase/c-Jun N-terminal Kinase) Activation

1 reference

12 December 2020

A specific inhibitor of the p38 mitogen activated protein kinase affects differentially the production of various cytokines by activated human T cells: dependence on CD28 signaling and preferential inhibition of IL-10 production

1 reference

12 December 2020

p38 mitogen-activated protein kinase mediates signal integration of TCR/CD28 costimulation in primary murine T cells

1 reference

12 December 2020

p38 mitogen-activated protein kinase regulates human T cell IL-5 synthesis

1 reference

12 December 2020

Role of p38 mitogen-activated protein kinase in a murine model of pulmonary inflammation

1 reference

12 December 2020

SB 239063, a potent p38 MAP kinase inhibitor, reduces inflammatory cytokine production, airways eosinophil infiltration, and persistence

1 reference

12 December 2020

Hapten-induced colitis associated with maintained Th1 and inflammatory responses in IFN-gamma receptor-deficient mice

1 reference

12 December 2020

p38 Mitogen-Activated Protein Kinase Inhibition Increases Cytokine Release by Macrophages In Vitro and During Infection In Vivo

1 reference

12 December 2020

Disease-modifying activity of SB 242235, a selective inhibitor of p38 mitogen-activated protein kinase, in rat adjuvant-induced arthritis

1 reference

12 December 2020

Identifiers

DOI

10.1136/GUT.50.4.507

1 reference

9 August 2017

1 reference

9 August 2017

1 reference