(Q40654612)

22 September 2017

title

Expression of constitutively activated Akt in the mammary gland leads to excess lipid synthesis during pregnancy and lactation (English)

1 reference

22 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12700340

25 December 2023

1 reference

https://api.crossref.org/works/10.1194/JLR.M300045-JLR200

25 December 2023

1 reference

https://api.crossref.org/works/10.1194/JLR.M300045-JLR200

25 December 2023

1 reference

https://api.crossref.org/works/10.1194/JLR.M300045-JLR200

25 December 2023

author

Kathryn L Schwertfeger

1

object named as

Kathryn L Schwertfeger

1 reference

22 September 2017

James L. McManaman

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12700340

25 December 2023

Carol A. Palmer

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12700340

25 December 2023

Margaret C. Neville

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12700340

25 December 2023

Steven M. Anderson

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12700340

25 December 2023

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12700340

25 December 2023

publication date

16 April 2003

1 reference

full work available at URL

22 September 2017

http://www.jlr.org/content/44/6/1100.full.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12700340

https://api.elsevier.com/content/article/PII:S0022227520311111?httpAccept=text/xml

25 December 2023

1 reference

https://api.crossref.org/works/10.1194/JLR.M300045-JLR200

https://api.elsevier.com/content/article/PII:S0022227520311111?httpAccept=text/plain

25 December 2023

1 reference

https://api.crossref.org/works/10.1194/JLR.M300045-JLR200

https://syndication.highwire.org/content/doi/10.1194/jlr.M300045-JLR200

25 December 2023

1 reference

https://api.crossref.org/works/10.1194/JLR.M300045-JLR200

Journal of Lipid Research

25 December 2023

published in

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22 September 2017

volume

44

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22 September 2017

issue

6

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22 September 2017

page(s)

1100-1112

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Activation of Stat5a and Stat5b by tyrosine phosphorylation is tightly linked to mammary gland differentiation.

22 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

Functional regulation of xanthine oxidoreductase expression and localization in the mouse mammary gland: evidence of a role in lipid secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

Regulation of milk lipid secretion and composition

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

Origin and secretion of milk lipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

Antibodies to the major insoluble milk fat globule membrane-associated protein: specific location in apical regions of lactating epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

Localization of xanthine oxidase in mammary-gland epithelium and capillary endothelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

Adipocyte differentiation-related protein is secreted into milk as a constituent of milk lipid globule membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

Golgi targeting of the GLUT1 glucose transporter in lactating mouse mammary gland

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

Glucose transporter expression in rat mammary gland

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

Identification and characterization of glucose transport proteins in plasma membrane- and Golgi vesicle-enriched fractions prepared from lactating rat mammary gland

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

Lack of correlation between activation of Jun-NH2-terminal kinase and induction of apoptosis after detachment of epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

Epidermal growth factor protects epithelial cells against Fas-induced apoptosis. Requirement for Akt activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

Cellular survival: a play in three Akts

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

Expression of a constitutively activated form of protein kinase B (c-Akt) in 3T3-L1 preadipose cells causes spontaneous differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

Regulation of GLUT1 gene transcription by the serine/threonine kinase Akt1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

Protein kinase B stimulates the translocation of GLUT4 but not GLUT1 or transferrin receptors in 3T3-L1 adipocytes by a pathway involving SNAP-23, synaptobrevin-2, and/or cellubrevin

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

Opposite translational control of GLUT1 and GLUT4 glucose transporter mRNAs in response to insulin. Role of mammalian target of rapamycin, protein kinase b, and phosphatidylinositol 3-kinase in GLUT1 mRNA translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

Regulation of neuronal survival by the serine-threonine protein kinase Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

IKKalpha provides an essential link between RANK signaling and cyclin D1 expression during mammary gland development

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

The osteoclast differentiation factor osteoprotegerin-ligand is essential for mammary gland development

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

Phosphatidylinositol 3-kinase is required for integrin-stimulated AKT and Raf-1/mitogen-activated protein kinase pathway activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

Mammary gland involution is delayed by activated Akt in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

Activation of Akt (protein kinase B) in mammary epithelium provides a critical cell survival signal required for tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

Quantitation of adipose conversion and triglycerides by staining intracytoplasmic lipids with Oil red O.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

Adipophilin is a specific marker of lipid accumulation in diverse cell types and diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

Transgenic mice expressing recombinant human protein C exhibit defects in lactation and impaired mammary gland development

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

Sodium dependence of nitrofurantoin active transport across mammary epithelia and effects of dipyridamole, nucleosides, and nucleobases

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

Epithelial mouse mammary cell line exhibiting normal morphogenesis in vivo and functional differentiation in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

Defective mammopoiesis, but normal hematopoiesis, in mice with a targeted disruption of the prolactin gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

Null mutation of the prolactin receptor gene produces multiple reproductive defects in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

A mutation in the epidermal growth factor receptor in waved-2 mice has a profound effect on receptor biochemistry that results in impaired lactation

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

Fibroblast growth factor (FGF) signaling through PI 3-kinase and Akt/PKB is required for embryoid body differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

Stat5a is mandatory for adult mammary gland development and lactogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

HIF1alpha is a critical regulator of secretory differentiation and activation, but not vascular expansion, in the mouse mammary gland

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

Mammary-derived signals activate programmed cell death during the first stage of mammary gland involution

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

Deletion of Stat3 blocks mammary gland involution and extends functional competence of the secretory epithelium in the absence of lactogenic stimuli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

Identification of wortmannin-sensitive targets in 3T3-L1 adipocytes. DissociationoOf insulin-stimulated glucose uptake and glut4 translocation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

Expression and localisation of GLUT1 and GLUT12 glucose transporters in the pregnant and lactating rat mammary gland.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

Regulation of the glucose transporter GLUT1 in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

Regulation of GLUT1 expression in the mammary gland.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

New perspectives in the regulation of hepatic glycolytic and lipogenic genes by insulin and glucose: a role for the transcription factor sterol regulatory element binding protein-1c

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300045-JLR200

Studies in human lactation: milk composition and daily secretion rates of macronutrients in the first year of lactation

21 January 2018

1

1 reference

https://api.crossref.org/works/10.1194/JLR.M300045-JLR200

Protein kinase expression during murine mammary development

25 December 2023

4

1 reference

https://api.crossref.org/works/10.1194/JLR.M300045-JLR200

Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor-dependent sympathetic neurons.

25 December 2023

18

1 reference

https://api.crossref.org/works/10.1194/JLR.M300045-JLR200

Mechanism of activation of protein kinase B by insulin and IGF-1

25 December 2023

29

1 reference

https://api.crossref.org/works/10.1194/JLR.M300045-JLR200

Activation of growth hormone receptor delivers an antiapoptotic signal: evidence for a role of Akt in this pathway

25 December 2023

31

1 reference

https://api.crossref.org/works/10.1194/JLR.M300045-JLR200

Possible role for protein kinase B in the anti-apoptotic effect of prolactin in rat Nb2 lymphoma cells

25 December 2023

34

1 reference

https://api.crossref.org/works/10.1194/JLR.M300045-JLR200

Delayed mammary gland involution in MMTV-AKT1 transgenic mice

25 December 2023

38

1 reference

https://api.crossref.org/works/10.1194/JLR.M300045-JLR200

Prolactin stimulates activation of c-jun N-terminal kinase (JNK).

25 December 2023

39

1 reference

https://api.crossref.org/works/10.1194/JLR.M300045-JLR200

Localization of the GLUT1 glucose transporter to brefeldin A-sensitive vesicles of differentiated CIT3 mouse mammary epithelial cells

25 December 2023

44

1 reference

https://api.crossref.org/works/10.1194/JLR.M300045-JLR200

Hormonal regulation of the glucose transporter GLUT I in the lactating rat mammary gland

25 December 2023

63

1 reference

https://api.crossref.org/works/10.1194/JLR.M300045-JLR200

Hormonal control of lipid metabolism in mouse mammary gland explants

25 December 2023

66

1 reference

https://api.crossref.org/works/10.1194/JLR.M300045-JLR200

25 December 2023

Identifiers

1 reference

22 September 2017

1 reference