(Q40659470)

English

An improved cell culture model based on 2/4/A1 cell monolayers for studies of intestinal drug transport: characterization of transport routes.

scientific article published on March 2003

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scholarly article

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Europe PubMed Central

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2 November 2019

An improved cell culture model based on 2/4/A1 cell monolayers for studies of intestinal drug transport: characterization of transport routes (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12669956%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Finn Hallböök

3

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2 November 2019

Kati-Sisko Vellonen

4

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2 November 2019

author name string

Staffan Tavelin

1

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2 November 2019

Jan Taipalensuu

2

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2 November 2019

Vanessa Moore

5

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2 November 2019

Per Artursson

6

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2 November 2019

publication date

1 March 2003

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2 November 2019

Pharmaceutical Research

1 reference

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2 November 2019

20

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2 November 2019

373-381

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2 November 2019

3

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2 November 2019

Evaluation of Biocoat intestinal epithelium differentiation environment (3-day cultured Caco-2 cells) as an absorption screening model with improved productivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12669956

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Properties of incompletely immortalized cell lines generated from a line established from temperature-sensitive SV40 T-antigen gene transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12669956

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differentiation is inhibited and a senescence pathway is activated when simian virus 40 tsA 58-transformed human retinoblasts are grown at the restrictive temperature

1 reference

https://pubmed.ncbi.nlm.nih.gov/12669956

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epithelial transport of drugs in cell culture. I: A model for studying the passive diffusion of drugs over intestinal absorptive (Caco-2) cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12669956

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transepithelial transport of drugs by the multidrug transporter in cultured Madin-Darby canine kidney cell epithelia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12669956

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A conditionally immortalized epithelial cell line for studies of intestinal drug transport.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12669956

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane transport of drugs in different regions of the intestinal tract of the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12669956

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction of the oral absorption of low-permeability drugs using small intestine-like 2/4/A1 cell monolayers

1 reference

https://pubmed.ncbi.nlm.nih.gov/12669956

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conditionally immortalized intestinal epithelial cells: novel approach for study of differentiated enterocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12669956

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uptake of the cephalosporin, cephalexin, by a dipeptide transport carrier in the human intestinal cell line, Caco-2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12669956

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate and antimitotic agents induce differentiation, p53 activation, and apoptosis in rodent neostriatal cell lines immortalized with the tsA58 allele of SV40 large T antigen

1 reference

https://pubmed.ncbi.nlm.nih.gov/12669956

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of an accelerated Caco-2 cell permeability model.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12669956

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New and better protocols for a short-term Caco-2 cell culture system

1 reference

https://pubmed.ncbi.nlm.nih.gov/12669956

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Redox aspects of Bcl-2 function.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12669956

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of breast cancer resistance protein in the bioavailability and fetal penetration of topotecan

1 reference

https://pubmed.ncbi.nlm.nih.gov/12669956

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Commitment to apoptosis is associated with changes in mitochondrial biogenesis and activity in cell lines conditionally immortalized with simian virus 40.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12669956

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional multidrug resistance protein (MRP1) lacking the N-terminal transmembrane domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/12669956

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional dissociation of paracellular permeability and transepithelial electrical resistance and disruption of the apical-basolateral intramembrane diffusion barrier by expression of a mutant tight junction membrane protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/12669956

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1 reference

https://pubmed.ncbi.nlm.nih.gov/12669956

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new diffusion chamber system for the determination of drug permeability coefficients across the human intestinal epithelium that are independent of the unstirred water layer

1 reference

https://pubmed.ncbi.nlm.nih.gov/12669956

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Persistence of abnormal chloride conductance regulation in transformed cystic fibrosis epithelia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12669956

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor inhibits glycylsarcosine transport and hPepT1 expression in a human intestinal cell line.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12669956

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis is induced at nonpermissive temperature by a transient increase in p53 in cell lines immortalized with temperature-sensitive SV40 large T-antigen gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/12669956

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation of gene expression of ten drug efflux proteins of the ATP-binding cassette transporter family in normal human jejunum and in human intestinal epithelial Caco-2 cell monolayers.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12669956

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transepithelial glycylsarcosine transport in intestinal Caco-2 cells mediated by expression of H(+)-coupled carriers at both apical and basal membranes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12669956

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epithelial transport of drugs in cell culture. VII: Effects of pharmaceutical surfactant excipients and bile acids on transepithelial permeability in monolayers of human intestinal epithelial (Caco-2) cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12669956

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p21Waf1/Cip1 acts in synergy with bcl-2 to confer multidrug resistance in a camptothecin-selected human lung-cancer cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/12669956

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis induced by differentiation or serum deprivation in an immortalized central nervous system neuronal cell line.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12669956

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MDCK (Madin-Darby canine kidney) cells: A tool for membrane permeability screening

1 reference

https://pubmed.ncbi.nlm.nih.gov/12669956

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/12669956

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alternative promoters and exons, somatic mutation and deregulation of the Bcl-2-Ig fusion gene in lymphoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/12669956

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1023/A:1022643802296

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12669956%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12669956%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

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