(Q40662922)

22 September 2017

title

ATP activates ataxia-telangiectasia mutated (ATM) in vitro. Importance of autophosphorylation (English)

1 reference

22 September 2017

0 references

Sergei Kozlov

1

1 reference

22 September 2017

Nuri Gueven

2

1 reference

22 September 2017

Katherine Keating

3

1 reference

22 September 2017

Jonathan Ramsay

4

1 reference

22 September 2017

Martin F Lavin

5

1 reference

22 September 2017

language of work or name

English

0 references

publication date

1 March 2003

1 reference

Journal of Biological Chemistry

22 September 2017

published in

1 reference

22 September 2017

volume

278

1 reference

22 September 2017

issue

11

1 reference

22 September 2017

page(s)

9309-9317

1 reference

describes a project that uses

22 September 2017

C3ABR

0 references

cites work

The genetic defect in ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

Identification of ataxia telangiectasia heterozygotes, a cancer prone population

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

Hypersensitivity of ataxia telangiectasia fibroblasts to ionizing radiation is associated with a repair deficiency of DNA double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

A single ataxia telangiectasia gene with a product similar to PI-3 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

Cell cycle checkpoint signaling through the ATM and ATR kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

Transcriptional downregulation of ATM by EGF is defective in ataxia-telangiectasia cells expressing mutant protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

Enhanced phosphorylation of p53 by ATM in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

ATM associates with and phosphorylates p53: mapping the region of interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

The ataxia-telangiectasia gene product, a constitutively expressed nuclear protein that is not up-regulated following genome damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

ATM: genome stability, neuronal development, and cancer cross paths

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

Participation of ATM in insulin signalling through phosphorylation of eIF-4E-binding protein 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

ATM-dependent phosphorylation of nibrin in response to radiation exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

Radiation-induced assembly of Rad51 and Rad52 recombination complex requires ATM and c-Abl

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

Functional link between BLM defective in Bloom's syndrome and the ataxia-telangiectasia-mutated protein, ATM

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

The DNA-dependent protein kinase, DNA-PK: 10 years and no ends in sight

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

Binding of inositol phosphate to DNA-PK and stimulation of double-strand break repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

Mammalian TOR: a homeostatic ATP sensor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

The Atr and Atm protein kinases associate with different sites along meiotically pairing chromosomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

Protein phosphatases regulate DNA-dependent protein kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

Cloning and expression of the ataxia-telangiectasia gene in baculovirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

Utilization of oriented peptide libraries to identify substrate motifs selected by ATM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

Solubilization and purification of enzymatically active glutathione S-transferase (pGEX) fusion proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

Purification and characterization of ATM from human placenta. A manganese-dependent, wortmannin-sensitive serine/threonine protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

Identification by mass spectrometry of the phosphorylated residue responsible for activation of the catalytic domain of myosin I heavy chain kinase, a member of the PAK/STE20 family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

TAK1 mediates the ceramide signaling to stress-activated protein kinase/c-Jun N-terminal kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

TAK1 mitogen-activated protein kinase kinase kinase is activated by autophosphorylation within its activation loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

Caffeine inhibits the checkpoint kinase ATM

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

Localization of a portion of extranuclear ATM to peroxisomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

Conformational diversity of catalytic cores of protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

Structures of unliganded and ATP-bound states of the Escherichia coli chaperonin GroEL by cryoelectron microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

ATP-dependent activation of the intermediate conductance, Ca2+-activated K+ channel, hIK1, is conferred by a C-terminal domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

Phosphatidic acid-mediated mitogenic activation of mTOR signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

Nuclear retention of ATM at sites of DNA double strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

FKBP12-Rapamycin-associated Protein (FRAP) Autophosphorylates at Serine 2481 under Translationally Repressive Conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

Ataxia telangiectasia: a human mutation with abnormal radiation sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

Ataxia telangiectasia. Neoplasia, untoward response to x-irradiation, and tuberous sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

On the nature of a defect in cells from individuals with ataxia-telangiectasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

Radiosensitivity in ataxia-telangiectasia: anomalies in radiation-induced cell cycle delay

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

The DNA-dependent protein kinase is inactivated by autophosphorylation of the catalytic subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

The product of the ATM gene is a 370-kDa nuclear phosphoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

Regulation of the activity of MEK kinase 1 (MEKK1) by autophosphorylation within the kinase activation domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300003200

21 January 2018

Identifiers

DOI

10.1074/JBC.M300003200

1 reference

22 September 2017

1 reference