(Q40663259)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12642586%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

title

Minimal BH3 peptides promote cell death by antagonizing anti-apoptotic proteins (English)

1 reference

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1 November 2019

0 references

Pierre-Francois Cartron

2

1 reference

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1 November 2019

Douglas R. Green

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12642586%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

author name string

Carole Moreau

1

1 reference

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1 November 2019

Abigail Hunt

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12642586%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Khaled Meflah

4

1 reference

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1 November 2019

Gerard Evan

6

1 reference

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1 November 2019

François M Vallette

7

1 reference

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1 November 2019

Philippe Juin

8

1 reference

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1 November 2019

language of work or name

English

0 references

publication date

17 March 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12642586%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

1 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12642586%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

volume

278

1 reference

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1 November 2019

issue

21

1 reference

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1 November 2019

page(s)

19426-19435

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12642586%20AND%20SRC:MED&resulttype=core&format=json

Apoptotic pathways: paper wraps stone blunts scissors

1 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209472200

The Bcl-2 protein family: arbiters of cell survival

21 January 2018

1 reference

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21 January 2018

1 reference

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Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209472200

Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis

21 January 2018

1 reference

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Identification of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209472200

Bcl-2-family proteins: the role of the BH3 domain in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209472200

Apoptosis. Till death us do part.

21 January 2018

1 reference

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Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

21 January 2018

1 reference

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PUMA induces the rapid apoptosis of colorectal cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209472200

PUMA, a novel proapoptotic gene, is induced by p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209472200

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209472200

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209472200

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209472200

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209472200

BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209472200

BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209472200

Movement of Bax from the cytosol to mitochondria during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209472200

BID: a novel BH3 domain-only death agonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209472200

Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209472200

Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209472200

Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209472200

Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209472200

c-Myc functionally cooperates with Bax to induce apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209472200

Involvement of the N-terminus of Bax in its intracellular localization and function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209472200

Preservation of mitochondrial structure and function after Bid- or Bax-mediated cytochrome c release

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209472200

c-Myc-induced sensitization to apoptosis is mediated through cytochrome c release

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209472200

Bax oligomerization is required for channel-forming activity in liposomes and to trigger cytochrome c release from mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209472200

Rapid kinetics of tBid-induced cytochrome c and Smac/DIABLO release and mitochondrial depolarization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209472200

Regulated targeting of BAX to mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209472200

The expression of a new variant of the pro-apoptotic molecule Bax, Baxpsi, is correlated with an increased survival of glioblastoma multiforme patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209472200

Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209472200

Induction of apoptosis in prostate carcinoma cells by BH3 peptides which inhibit Bak/Bcl-2 interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209472200

Direct addition of BimL to mitochondria does not lead to cytochrome c release

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209472200

Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209472200

Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209472200

Bcl-2 and Bax interactions in mitochondria probed with green fluorescent protein and fluorescence resonance energy transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209472200

Discovery of small-molecule inhibitors of Bcl-2 through structure-based computer screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209472200

Structure of Bax: coregulation of dimer formation and intracellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209472200

Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209472200

21 January 2018

Identifiers

DOI

10.1074/JBC.M209472200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12642586%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference