(Q40663965)

English

Smad3 potentiates transforming growth factor beta (TGFbeta )-induced apoptosis and expression of the BH3-only protein Bim in WEHI 231 B lymphocytes

scientific article published on 13 March 2003

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scholarly article

1 reference

Europe PubMed Central

22 September 2017

Smad3 potentiates transforming growth factor beta (TGFbeta )-induced apoptosis and expression of the BH3-only protein Bim in WEHI 231 B lymphocytes (English)

1 reference

Europe PubMed Central

22 September 2017

1 reference

based on heuristic

inferred from title

author name string

Gary M Wildey

1

1 reference

Europe PubMed Central

22 September 2017

Supriya Patil

2

1 reference

Europe PubMed Central

22 September 2017

Philip H Howe

3

1 reference

Europe PubMed Central

22 September 2017

language of work or name

0 references

publication date

13 March 2003

1 reference

Europe PubMed Central

22 September 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

22 September 2017

278

1 reference

Europe PubMed Central

22 September 2017

18069-18077

1 reference

Europe PubMed Central

22 September 2017

20

1 reference

Europe PubMed Central

22 September 2017

TGF-beta signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

Regulation of Smad activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

Hgs (Hrs), a FYVE domain protein, is involved in Smad signaling through cooperation with SARA.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

The adaptor molecule Disabled-2 links the transforming growth factor beta receptors to the Smad pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

Disabled-2 colocalizes with the LDLR in clathrin-coated pits and interacts with AP-2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

Transforming growth factor beta activation of p44mapk in proliferating cultures of epithelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

TGF-beta induces fibronectin synthesis through a c-Jun N-terminal kinase-dependent, Smad4-independent pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

ATF-2 is a common nuclear target of Smad and TAK1 pathways in transforming growth factor-beta signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

Phosphatidylinositol 3-kinase function is required for transforming growth factor beta-mediated epithelial to mesenchymal transition and cell migration.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

RhoB is stabilized by transforming growth factor beta and antagonizes transcriptional activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

Extracellular signal-regulated kinase and the small GTP-binding protein, Rac, contribute to the effects of transforming growth factor-beta1 on gene expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

Transforming growth factor-beta1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

Induction of apoptosis in cultured hepatocytes and in regressing liver by transforming growth factor beta 1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

Transforming growth factor-beta 1 induces apoptosis independently of p53 and selectively reduces expression of Bcl-2 in multipotent hematopoietic cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

TGF beta 1 inhibits NF-kappa B/Rel activity inducing apoptosis of B cells: transcriptional activation of I kappa B alpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

Transforming growth factor beta induces caspase 3-independent cleavage of alphaII-spectrin (alpha-fodrin) coincident with apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

Smad7 is induced by CD40 and protects WEHI 231 B-lymphocytes from transforming growth factor-beta -induced growth inhibition and apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

TGF-beta-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

A novel mitochondrial septin-like protein, ARTS, mediates apoptosis dependent on its P-loop motif

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

Transforming growth factor beta 1 induces apoptosis through cleavage of BAD in a Smad3-dependent mechanism in FaO hepatoma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

Bim: a novel member of the Bcl-2 family that promotes apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

Identification of novel isoforms of the BH3 domain protein Bim which directly activate Bax to trigger apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

Molecular cloning and characterization of six novel isoforms of human Bim, a member of the proapoptotic Bcl-2 family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

Activation of mitochondrial voltage-dependent anion channel by apro-apoptotic BH3-only protein Bim

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

Bcl-2 proteins: regulators of apoptosis or of mitochondrial homeostasis?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

The proapoptotic BH3-only protein bim is expressed in hematopoietic, epithelial, neuronal, and germ cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

Downregulation of Bim, a proapoptotic relative of Bcl-2, is a pivotal step in cytokine-initiated survival signaling in murine hematopoietic progenitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: protein kinase B-enhanced cell survival through maintenance of mitochondrial integrity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

Induction of apoptosis by Smad3 and down-regulation of Smad3 expression in response to TGF-beta in human normal lung epithelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

Smad7 is an activin-inducible inhibitor of activin-induced growth arrest and apoptosis in mouse B cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

Differential inhibition of Smad6 and Smad7 on bone morphogenetic protein- and activin-mediated growth arrest and apoptosis in B cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

LY294002-mediated inhibition of phosphatidylinositol 3-kinase activity triggers growth inhibition and apoptosis in CD40-triggered Ramos-Burkitt lymphoma B cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

Critical role of Smads and AP-1 complex in transforming growth factor-beta -dependent apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

Smad4 and FAST-1 in the assembly of activin-responsive factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

Smad2 and Smad3 positively and negatively regulate TGF beta-dependent transcription through the forkhead DNA-binding protein FAST2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

The role of FAST-1 and Smads in transcriptional regulation by activin during early Xenopus embryogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

Gene structure alternative splicing, and chromosomal localization of pro-apoptotic Bcl-2 relative Bim

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85alpha.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211958200

21 January 2018

Identifiers

10.1074/JBC.M211958200

1 reference

Europe PubMed Central

22 September 2017

release_qppoa5qvzjgyfp2kv4epmbwuce

1 reference

https://api.fatcat.wiki/v0/release/qppoa5qvzjgyfp2kv4epmbwuce

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

22 September 2017

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