(Q40666357)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12619154%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

title

Deletion of Brca2 exon 27 causes hypersensitivity to DNA crosslinks, chromosomal instability, and reduced life span in mice (English)

1 reference

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1 November 2019

1 reference

5

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1 November 2019

author name string

Greg Donoho

1

1 reference

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1 November 2019

Mark A Brenneman

2

1 reference

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1 November 2019

Tracy X Cui

3

1 reference

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1 November 2019

Dorit Donoviel

4

1 reference

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1 November 2019

Edwin H Goodwin

6

1 reference

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1 November 2019

David J Chen

7

1 reference

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1 November 2019

Paul Hasty

8

1 reference

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1 November 2019

publication date

1 April 2003

1 reference

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Genes, Chromosomes and Cancer

1 November 2019

published in

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1 November 2019

volume

36

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1 November 2019

issue

4

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1 November 2019

page(s)

317-331

1 reference

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Cross-sensitivity of gamma-ray-sensitive hamster mutants to cross-linking agents

1 November 2019

cites work

1 reference

Mutant rodent cell lines sensitive to ultraviolet light, ionizing radiation and cross-linking agents: a comprehensive survey of genetic and biochemical characteristics

21 January 2018

1 reference

A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53

21 January 2018

1 reference

Interaction between the product of the breast cancer susceptibility gene BRCA2 and DSS1, a protein functionally conserved from yeast to mammals

21 January 2018

1 reference

DNA double-strand break repair proteins are required to cap the ends of mammalian chromosomes

21 January 2018

1 reference

7 January 2021

Expression of BRC repeats in breast cancer cells disrupts the BRCA2-Rad51 complex and leads to radiation hypersensitivity and loss of G(2)/M checkpoint control

1 reference

7 January 2021

Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells

1 reference

7 January 2021

The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment

1 reference

7 January 2021

Tumorigenesis and a DNA repair defect in mice with a truncating Brca2 mutation

1 reference

7 January 2021

The XRCC2 and XRCC3 repair genes are required for chromosome stability in mammalian cells

1 reference

7 January 2021

Repair of DNA interstrand cross-links

1 reference

7 January 2021

Mammalian recombination-repair genes XRCC2 and XRCC3 promote correct chromosome segregation

1 reference

7 January 2021

Ku acts in a unique way at the mammalian telomere to prevent end joining

1 reference

7 January 2021

Multiple possible sites of BRAC2 interacting with DNA repair protein RAD51

1 reference

7 January 2021

Cancer-susceptibility genes. Gatekeepers and caretakers

1 reference

7 January 2021

Inhibition of breast and brain cancer cell growth by BCCIPalpha, an evolutionarily conserved nuclear protein that interacts with BRCA2

1 reference

7 January 2021

XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages

1 reference

7 January 2021

Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos

1 reference

7 January 2021

The BRCA2 gene product functionally interacts with p53 and RAD51

1 reference

7 January 2021

RAB22 and RAB163/mouse BRCA2: proteins that specifically interact with the RAD51 protein

1 reference

7 January 2021

BRCA2 is required for homology-directed repair of chromosomal breaks

1 reference

7 January 2021

Involvement of Brca2 in DNA repair

1 reference

7 January 2021

High-LET radiations induce a large proportion of non-rejoining DNA breaks

1 reference

7 January 2021

Mammalian Ku86 protein prevents telomeric fusions independently of the length of TTAGGG repeats and the G-strand overhang

1 reference

7 January 2021

Analysis of murine Brca2 reveals conservation of protein-protein interactions but differences in nuclear localization signals

1 reference

7 January 2021

Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2

1 reference

7 January 2021

A targeted disruption of the murine Brca1 gene causes gamma-irradiation hypersensitivity and genetic instability.

1 reference

7 January 2021

Genetic variation among 129 substrains and its importance for targeted mutagenesis in mice

1 reference

7 January 2021

Rad51-deficient vertebrate cells accumulate chromosomal breaks prior to cell death

1 reference

7 January 2021

Truncated BRCA2 is cytoplasmic: implications for cancer-linked mutations

1 reference

7 January 2021

Brca2 is required for embryonic cellular proliferation in the mouse

1 reference

7 January 2021

The Rad51 paralog Rad51B promotes homologous recombinational repair

1 reference

7 January 2021

Chromosome instability and defective recombinational repair in knockout mutants of the five Rad51 paralogs

1 reference

7 January 2021

Correction of chromosomal instability and sensitivity to diverse mutagens by a cloned cDNA of the XRCC3 DNA repair gene

1 reference

7 January 2021

The contribution of homologous recombination in preserving genome integrity in mammalian cells

1 reference

7 January 2021

Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines

1 reference

7 January 2021

Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences

1 reference

7 January 2021

Deletion of Ku86 causes early onset of senescence in mice

1 reference

7 January 2021

RAD51 interacts with the evolutionarily conserved BRC motifs in the human breast cancer susceptibility gene brca2

1 reference

7 January 2021

Identification of the breast cancer susceptibility gene BRCA2

1 reference

7 January 2021

Deficiency of human BRCA2 leads to impaired homologous recombination but maintains normal nonhomologous end joining

1 reference

7 January 2021

Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells

1 reference

7 January 2021

Mre11 is essential for the maintenance of chromosomal DNA in vertebrate cells

1 reference

7 January 2021

Interaction with BRCA2 suggests a role for filamin-1 (hsFLNa) in DNA damage response

1 reference

7 January 2021

Identifiers

DOI

10.1002/GCC.10148

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12619154%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference