(Q40667329)

22 September 2017

Alternative pathway of metronidazole activation in Trichomonas vaginalis hydrogenosomes (English)

1 reference

22 September 2017

Trichomonas vaginalis

0 references

metronidazole

1 reference

ChEBI release 2020-05-28

1 reference

Ivan Hrdý

1

0 references

author name string

Richard Cammack

2

1 reference

22 September 2017

Pavel Stopka

3

1 reference

22 September 2017

Jaroslav Kulda

4

1 reference

22 September 2017

Jan Tachezy

5

1 reference

22 September 2017

language of work or name

English

0 references

publication date

1 December 2005

1 reference

Antimicrobial Agents and Chemotherapy

22 September 2017

1 reference

22 September 2017

49

1 reference

22 September 2017

12

1 reference

22 September 2017

5033-5036

1 reference

Mitochondrial-type assembly of FeS centers in the hydrogenosomes of the amitochondriate eukaryote Trichomonas vaginalis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1315937

Reactivity of reduced [2Fe-2S] ferredoxins parallels host susceptibility to nitroimidazoles

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1315937

Methods for cultivation of luminal parasitic protists of clinical importance

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1315937

Trichomonads, hydrogenosomes and drug resistance

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1315937

Metronidazole resistance of Trichomonas vaginalis as a cause of treatment failure in trichomoniasis--A case report

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1315937

Anaerobic pyruvate metabolism of Tritrichomonas foetus and Trichomonas vaginalis hydrogenosomes

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1315937

Reduced transcription of the ferredoxin gene in metronidazole-resistant Trichomonas vaginalis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1315937

Antitrichomonad action, mutagenicity, and reduction of metronidazole and other nitroimidazoles

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1315937

Nitroimidazole drugs--action and resistance mechanisms. II. Mechanisms of resistance

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1315937

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1315937

Mechanisms of in vitro development of resistance to metronidazole in Trichomonas vaginalis

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1315937

Reductive activation of nitroimidazoles in anaerobic microorganisms

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1315937

Trichomonas hydrogenosomes contain the NADH dehydrogenase module of mitochondrial complex I.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1315937

Targeted gene replacement of a ferredoxin gene in Trichomonas vaginalis does not lead to metronidazole resistance

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1315937

Iron-ascorbate cleavable malic enzyme from hydrogenosomes of Trichomonas vaginalis: purification and characterization.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1315937

Metabolic differences between metronidazole resistant and susceptible strains of Tritrichomonas foetus.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1315937

Hydrogenosomal ferredoxin of the anaerobic protozoon, Tritrichomonas foetus

19 August 2018

1 reference

12 December 2020

Distinct reduction of nitrofurans and metronidazole to free radical metabolites by Tritrichomonas foetus hydrogenosomal and cytosolic enzymes

1 reference

12 December 2020

The generation of metronidazole radicals in hydrogenosomes isolated from Trichomonas vaginalis

1 reference

12 December 2020

Comparative study of ferredoxin-linked and oxygen-metabolizing enzymes of trichomonads

1 reference

12 December 2020

In vitro induced anaerobic resistance to metronidazole in Trichomonas vaginalis

1 reference

12 December 2020

10.1128/AAC.49.12.5033-5036.2005

Identifiers

DOI

1 reference

22 September 2017

1 reference

22 September 2017

1 reference