(Q40669326)

English

A single site-specific trans-opened 7,8,9,10-tetrahydrobenzo[a]pyrene 7,8-diol 9,10-epoxide N2-deoxyguanosine adduct induces mutations at multiple sites in DNA.

scientific article published on 20 February 2003

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

A single site-specific trans-opened 7,8,9,10-tetrahydrobenzo[a]pyrene 7,8-diol 9,10-epoxide N2-deoxyguanosine adduct induces mutations at multiple sites in DNA. (English)

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

author name string

Pavel Kramata

1

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Barbara Zajc

2

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Jane M Sayer

3

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Donald M Jerina

4

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Caroline S-J Wei

5

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

language of work or name

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publication date

20 February 2003

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Europe PubMed Central

PubMed publication ID

22 September 2017

number of pages

9

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based on heuristic

inferred from page(s)

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

22 September 2017

278

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Europe PubMed Central

PubMed publication ID

22 September 2017

17

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

14940-14948

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Synthesis of (+-)-7.beta.,8.alpha.-dihydroxy-9.beta.,10.beta.-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene, a potential metabolite of the carcinogen benzo[a]pyrene with stereochemistry related to the antileukemic triptolides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

Absolute sterochemistry of the highly mutagenic 7,8-diol 9,10-epoxides derived from the potent carcinogen trans-7,8-dihydroxy-7,8-dihydrobenzol[a]pyrene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

Metabolism of benzo[a]pyrene. VI. Stereoselective metabolism of benzo[a]pyrene and benzo[a]pyrene 7,8-dihydrodiol to diol epoxides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

Differences in mutagenicity of the optical enantiomers of the diastereomeric benzo[a]pyrene 7,8-diol-9,10-epoxides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

Tumorigenicity of the optical enantiomers of the diastereomeric benzo[a]pyrene 7,8-diol-9,10-epoxides in newborn mice: exceptional activity of (+)-7beta,8alpha-dihydroxy-9alpha,10alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

Effect of excision repair by diploid human fibroblasts on the kinds and locations of mutations induced by (+/-)-7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10- tetrahydrobenzo[a]pyrene in the coding region of the HPRT gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

Mutagenic selectivity at the HPRT locus in V-79 cells: comparison of mutations caused by bay-region benzo[a]pyrene 7,8-diol-9,-10-epoxide enantiomers with high and low carcinogenic activity.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

Marked differences in base selectivity between DNA and the free nucleotides upon adduct formation from Bay- and Fjord-region diol epoxides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

Solution conformation of the major adduct between the carcinogen (+)-anti-benzo[a]pyrene diol epoxide and DNA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

Nucleotide excision repair in mammalian cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

Molecular mechanism of nucleotide excision repair.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

The Y-family of DNA polymerases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

Human DNA polymerase kappa synthesizes DNA with extraordinarily low fidelity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

Human DNA polymerase iota promiscuous mismatch extension

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

Multiple mutations in a shuttle vector modified by ultraviolet irradiation, (+/-)-7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene, and aflatoxin B(1) have different properties than single mutations and may be genera

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

Molecular analysis of ERCC2 mutations in the repair deficient hamster mutants UVL-1 and V-H1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

TFIIH: a key component in multiple DNA transactions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

Characterization of the mutational profile of (+)-7R,8S-dihydroxy-9S, 10R-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene at the hypoxanthine (guanine) phosphoribosyltransferase gene in repair-deficient Chinese hamster V-H1 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

Benzo[a]pyrene diol epoxide-deoxyguanosine adducts are accurately bypassed by yeast DNA polymerase zeta in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

Stereospecific differences in repair by human cell extracts of synthesized oligonucleotides containing trans-opened 7,8,9, 10-tetrahydrobenzo[a]pyrene 7,8-diol 9,10-epoxide N2-dG adduct stereoisomers located within the human K-ras codon 12 sequence

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

Sequence context profoundly influences the mutagenic potency of trans-opened benzo[a]pyrene 7,8-diol 9,10-epoxide-purine nucleoside adducts in site-specific mutation studies

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

Dose-dependent differences in the profile of mutations induced by an ultimate carcinogen from benzo[a]pyrene.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

Single-nucleotide polymorphism identification assays using a thermostable DNA polymerase and delayed extraction MALDI-TOF mass spectrometry

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

The Major, N2-Gua Adduct of the (+)-anti-Benzo[a]pyrene Diol Epoxide Is Capable of Inducing G.fwdarw.A and G.fwdarw.C, in Addition to G.fwdarw.T, Mutations

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

Base pair conformation-dependent excision of benzo[a]pyrene diol epoxide-guanine adducts by human nucleotide excision repair enzymes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

Carcinogen-induced frameshift mutagenesis in repetitive sequences

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

trans-Lesion synthesis past bulky benzo[a]pyrene diol epoxide N2-dG and N6-dA lesions catalyzed by DNA bypass polymerases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

Preferential misincorporation of purine nucleotides by human DNA polymerase eta opposite benzo[a]pyrene 7,8-diol 9,10-epoxide deoxyguanosine adducts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

Differences between the mutational consequences of replication of cis- and trans-opened benzo[a]pyrene 7,8-diol 9,10-epoxide-deoxyguanosine adducts in M13mp7L2 constructs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

Mutational properties of the primary aflatoxin B1-DNA adduct

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

The aflatoxin B(1) formamidopyrimidine adduct plays a major role in causing the types of mutations observed in human hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

Influence of flanking sequence context on the mutagenicity of acetylaminofluorene-derived DNA adducts in mammalian cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

Intercalation of aflatoxin B1 in two oligodeoxynucleotide adducts: comparative 1H NMR analysis of d(ATCAFBGAT).d(ATCGAT) and d(ATAFBGCAT)2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

Structural refinement of the 8,9-dihydro-8-(N7-guanyl)-9-hydroxy-aflatoxin B(1) adduct in a 5'-Cp(AFB)G-3' sequence

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

Translesional synthesis past acetylaminofluorene-derived DNA adducts catalyzed by human DNA polymerase kappa and Escherichia coli DNA polymerase IV.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

Site-specific rates of excision repair of benzo[a]pyrene diol epoxide adducts in the hypoxanthine phosphoribosyltransferase gene of human fibroblasts: correlation with mutation spectra

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

Metabolic activation of benzo(a)pyrene proceeds by a diol-epoxide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

Influence of benzo[a]pyrene diol epoxide chirality on solution conformations of DNA covalent adducts: the (-)-trans-anti-[BP]G.C adduct structure and comparison with the (+)-trans-anti-[BP]G.C enantiomer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

Fidelity of human DNA polymerase eta

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

From gels to chips: "minisequencing" primer extension for analysis of point mutations and single nucleotide polymorphisms

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

Fidelity of translesional synthesis past benzo[a]pyrene diol epoxide-2'-deoxyguanosine DNA adducts: marked effects of host cell, sequence context, and chirality

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

Structural characterization of a (+)-trans-anti-benzo[a]pyrene-DNA adduct using NMR, restrained energy minimization, and molecular dynamics

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

Structural characterization of an N-acetyl-2-aminofluorene (AAF) modified DNA oligomer by NMR, energy minimization, and molecular dynamics

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211557200

21 January 2018

Identifiers

10.1074/JBC.M211557200

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

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