(Q40681049)

English

Quantitative drug interactions prediction system (Q-DIPS): a dynamic computer-based method to assist in the choice of clinically relevant in vivo studies

scientific article published on January 2001

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scholarly article

1 reference

Europe PubMed Central

22 September 2017

Quantitative drug interactions prediction system (Q-DIPS): a dynamic computer-based method to assist in the choice of clinically relevant in vivo studies (English)

1 reference

Europe PubMed Central

22 September 2017

author name string

Bonnabry P

1

1 reference

Europe PubMed Central

22 September 2017

Sievering J

2

1 reference

Europe PubMed Central

22 September 2017

Leemann T

3

1 reference

Europe PubMed Central

22 September 2017

Dayer P

4

1 reference

Europe PubMed Central

22 September 2017

publication date

1 January 2001

1 reference

Europe PubMed Central

22 September 2017

Clinical Pharmacokinetics

1 reference

Europe PubMed Central

22 September 2017

40

1 reference

Europe PubMed Central

22 September 2017

631-640

1 reference

Europe PubMed Central

22 September 2017

9

1 reference

Europe PubMed Central

22 September 2017

https://scigraph.springernature.com/pub.10.2165/00003088-200140090-00001

0 references

Inhibitors of alprazolam metabolism in vitro: effect of serotonin-reuptake-inhibitor antidepressants, ketoconazole and quinidine

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200140090-00001

21 January 2018

Integrated cytochrome P450 reaction phenotyping: attempting to bridge the gap between cDNA-expressed cytochromes P450 and native human liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/11605713

12 December 2020

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FDA evaluations using in vitro metabolism to predict and interpret in vivo metabolic drug-drug interactions: impact on labeling.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11605713

12 December 2020

based on heuristic

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Prediction of drug-drug interactions of zonisamide metabolism in humans from in vitro data

1 reference

https://pubmed.ncbi.nlm.nih.gov/11605713

12 December 2020

based on heuristic

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INTERACTION OF FLUCONAZOLE WITH CYCLOSPORIN

1 reference

https://pubmed.ncbi.nlm.nih.gov/11605713

12 December 2020

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Recombinant yeast in drug metabolism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11605713

12 December 2020

based on heuristic

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Design of in vitro studies to predict in vivo inhibitory drug-drug interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/11605713

12 December 2020

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Cellular uptake of fluvastatin, an inhibitor of HMG-CoA reductase, by rat cultured hepatocytes and human aortic endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11605713

12 December 2020

based on heuristic

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Cytochromes P450 expression systems

1 reference

https://pubmed.ncbi.nlm.nih.gov/11605713

12 December 2020

based on heuristic

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P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11605713

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Hepatic vectorial transport of xenobiotics

1 reference

https://pubmed.ncbi.nlm.nih.gov/11605713

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Application of human liver microsomes in metabolism-based drug-drug interactions: in vitro-in vivo correlations and the Abbott Laboratories experience

1 reference

https://pubmed.ncbi.nlm.nih.gov/11605713

12 December 2020

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Nonspecific binding to microsomes: impact on scale-up of in vitro intrinsic clearance to hepatic clearance as assessed through examination of warfarin, imipramine, and propranolol.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11605713

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative drug interactions prediction system (Q-DIPS): a computer-based prediction and management support system for drug metabolism interactions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11605713

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human cytochrome P450s: selectivity and measurement in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/11605713

12 December 2020

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In vitro approaches to predicting drug interactions in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11605713

12 December 2020

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Uptake of organic anions by isolated rat hepatocytes. A classification in terms of ATP-dependency.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11605713

12 December 2020

based on heuristic

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Na(+)-independent multispecific anion transporter mediates active transport of pravastatin into rat liver.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11605713

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction between cyclosporine and fluconazole in renal allograft recipients

1 reference

https://pubmed.ncbi.nlm.nih.gov/11605713

12 December 2020

based on heuristic

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Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/11605713

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The human hepatic cytochromes P450 involved in drug metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/11605713

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessment and reporting of clinical pharmacology information in drug labeling

1 reference

https://pubmed.ncbi.nlm.nih.gov/11605713

12 December 2020

based on heuristic

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Quantitative prediction of in vivo drug clearance and drug interactions from in vitro data on metabolism, together with binding and transport

1 reference

https://pubmed.ncbi.nlm.nih.gov/11605713

12 December 2020

based on heuristic

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Extrapolation of in vitro enzyme induction data to humans in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/11605713

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytochrome P450 enzymes and drug metabolism--basic concepts and methods of assessment

1 reference

https://pubmed.ncbi.nlm.nih.gov/11605713

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical importance of hepatic cytochrome P450 in drug metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/11605713

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition and induction of cytochrome P450 and the clinical implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/11605713

12 December 2020

based on heuristic

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Drug-drug interactions of new active substances: mibefradil example

1 reference

https://pubmed.ncbi.nlm.nih.gov/11605713

12 December 2020

based on heuristic

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Fluconazole-cyclosporine interaction: a dose-dependent effect?

1 reference

https://pubmed.ncbi.nlm.nih.gov/11605713

12 December 2020

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Presystemic extraction: mechanisms and consequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/11605713

12 December 2020

based on heuristic

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Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/11605713

12 December 2020

based on heuristic

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Inhibition and induction of human cytochrome P450 (CYP) enzymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/11605713

12 December 2020

based on heuristic

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Human cytochrome P450 enzymes expressed in bacteria: reagents to probe molecular interactions in toxicology

1 reference

https://pubmed.ncbi.nlm.nih.gov/11605713

12 December 2020

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Interindividual variability in catalytic activity and immunoreactivity of three major human liver cytochrome P450 isozymes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11605713

12 December 2020

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Molecular genetics of the human cytochrome P450 monooxygenase superfamily

1 reference

https://pubmed.ncbi.nlm.nih.gov/11605713

12 December 2020

based on heuristic

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Clinically significant drug interactions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11605713

12 December 2020

based on heuristic

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Specificity of substrate and inhibitor probes for cytochrome P450s: evaluation of in vitro metabolism using cDNA-expressed human P450s and human liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/11605713

12 December 2020

based on heuristic

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Assessment of the quality and quantity of drug-drug interaction studies in recent NDA submissions: study design and data analysis issues

1 reference

https://pubmed.ncbi.nlm.nih.gov/11605713

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Carrier-mediated transport in the hepatic distribution and elimination of drugs, with special reference to the category of organic cations

1 reference

https://pubmed.ncbi.nlm.nih.gov/11605713

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Update: clinically significant cytochrome P-450 drug interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/11605713

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of cytochrome P450 enzymes in drug-drug interactions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11605713

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2165/00003088-200140090-00001

1 reference

Europe PubMed Central

22 September 2017

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0 references

release_csirenpvzjarncwqfm5v3o2jki

1 reference

https://api.fatcat.wiki/v0/release/csirenpvzjarncwqfm5v3o2jki

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

22 September 2017

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