(Q40681333)

22 September 2017

title

Quality and quantity of TFH cells are critical for broad antibody development in SHIVAD8 infection (English)

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22 September 2017

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T follicular helper cell

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1

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22 September 2017

17

John R Mascola

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22 September 2017

13

Brandon F Keele

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22 September 2017

19

Richard A Koup

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22 September 2017

11

Adrian B McDermott

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22 September 2017

Rebecca M Lynch

2

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22 September 2017

Rajeev Gautam

3

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22 September 2017

Rodrigo Matus-Nicodemos

4

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22 September 2017

Stephen D Schmidt

5

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22 September 2017

Kristin L Boswell

6

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22 September 2017

Sam Darko

7

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22 September 2017

Patrick Wong

8

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22 September 2017

Zizhang Sheng

9

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22 September 2017

Constantinos Petrovas

10

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22 September 2017

Robert A Seder

12

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22 September 2017

Lawrence Shapiro

14

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22 September 2017

Daniel C Douek

15

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22 September 2017

Yoshiaki Nishimura

16

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22 September 2017

Malcolm A Martin

18

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22 September 2017

language of work or name

English

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publication date

1 July 2015

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Science Translational Medicine

22 September 2017

published in

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22 September 2017

volume

7

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22 September 2017

issue

298

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22 September 2017

page(s)

298ra120

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Broadly neutralizing antibodies and the search for an HIV-1 vaccine: the end of the beginning

22 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Follicular helper CD4 T cells (TFH)

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

CD4 T follicular helper cell dynamics during SIV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Follicular helper T cells: lineage and location

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Molecular programming of B cell memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Pathogenicity and mucosal transmissibility of the R5-tropic simian/human immunodeficiency virus SHIV(AD8) in rhesus macaques: implications for use in vaccine studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Most rhesus macaques infected with the CCR5-tropic SHIV(AD8) generate cross-reactive antibodies that neutralize multiple HIV-1 strains

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Rapid development of glycan-specific, broad, and potent anti-HIV-1 gp120 neutralizing antibodies in an R5 SIV/HIV chimeric virus infected macaque

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Expansion of HIV-specific T follicular helper cells in chronic HIV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Plasma levels of soluble CD14 independently predict mortality in HIV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Late interleukin-6 escalates T follicular helper cell responses and controls a chronic viral infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Unique gene expression program of human germinal center T helper cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Cytokine-secreting follicular T cells shape the antibody repertoire

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Analysis of immunoglobulin transcripts and hypermutation following SHIV(AD8) infection and protein-plus-adjuvant immunization

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Single-cell and deep sequencing of IgG-switched macaque B cells reveal a diverse Ig repertoire following immunization

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

IMGT, the international ImMunoGeneTics information system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Breadth of human immunodeficiency virus-specific neutralizing activity in sera: clustering analysis and association with clinical variables

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Characteristics of the earliest cross-neutralizing antibody response to HIV-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Breadth of neutralizing antibody response to human immunodeficiency virus type 1 is affected by factors early in infection but does not influence disease progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Inadequate T follicular cell help impairs B cell immunity during HIV infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Neutralizing antibodies generated during natural HIV-1 infection: good news for an HIV-1 vaccine?

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

B cells in HIV infection and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Prevalence of broadly neutralizing antibody responses during chronic HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Clonal selection in the germinal centre by regulated proliferation and hypermutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

T-cell subsets in the germinal center.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Persistent antigen and germinal center B cells sustain T follicular helper cell responses and phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Bcl6 mediates the development of T follicular helper cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Human circulating PD-1+CXCR3-CXCR5+ memory Tfh cells are highly functional and correlate with broadly neutralizing HIV antibody responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Factors associated with the development of cross-reactive neutralizing antibodies during human immunodeficiency virus type 1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

HIV-1 neutralizing antibodies: understanding nature's pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Follicular B helper T cells in antibody responses and autoimmunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

T follicular helper cell dynamics in germinal centers

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Induction of ICOS+CXCR3+CXCR5+ TH cells correlates with antibody responses to influenza vaccination

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Human circulating influenza-CD4+ ICOS1+IL-21+ T cells expand after vaccination, exert helper function, and predict antibody responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Circulating precursor CCR7(lo)PD-1(hi) CXCR5⁺ CD4⁺ T cells indicate Tfh cell activity and promote antibody responses upon antigen reexposure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Loss of circulating CD4 T cells with B cell helper function during chronic HIV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Viral persistence redirects CD4 T cell differentiation toward T follicular helper cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Short- and long-term clinical outcomes in rhesus monkeys inoculated with a highly pathogenic chimeric simian/human immunodeficiency virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Characterization of stable, soluble trimers containing complete ectodomains of human immunodeficiency virus type 1 envelope glycoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

A method for identification of HIV gp140 binding memory B cells in human blood

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Tiered categorization of a diverse panel of HIV-1 Env pseudoviruses for assessment of neutralizing antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Isolation of antibody V(D)J sequences from single cell sorted rhesus macaque B cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Somatic Populations of PGT135-137 HIV-1-Neutralizing Antibodies Identified by 454 Pyrosequencing and Bioinformatics

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Clustal W and Clustal X version 2.0

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

10.1126/SCITRANSLMED.AAB3964

21 January 2018

Identifiers

DOI

1 reference

22 September 2017

1 reference