(Q40685298)

22 September 2017

title

Secretion of apolipoprotein E by brain glia requires protein prenylation and is suppressed by statins (English)

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22 September 2017

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Asha Naidu

1

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22 September 2017

Qiang Xu

series ordinal

2

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22 September 2017

Rosanne Catalano

series ordinal

3

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22 September 2017

Barbara Cordell

series ordinal

4

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22 September 2017

publication date

1 December 2002

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22 September 2017

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22 September 2017

volume

958

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22 September 2017

issue

1

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22 September 2017

page(s)

100-111

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Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition

22 September 2017

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7 January 2021

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7 January 2021

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The neurobiology of apolipoproteins and their receptors in the CNS and Alzheimer's disease

7 January 2021

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Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

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Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase

7 January 2021

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Simvastatin strongly reduces levels of Alzheimer's disease beta -amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo

7 January 2021

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Alendronate mechanism of action: geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro

7 January 2021

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Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease

7 January 2021

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Interactions of apolipoprotein E genotype, total cholesterol level, age, and sex in prediction of Alzheimer's disease: a case-control study

7 January 2021

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Statins and the risk of dementia

7 January 2021

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Statins as a newly recognized type of immunomodulator

7 January 2021

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Lipoproteins in the central nervous system

7 January 2021

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Ras CAAX Peptidomimetic FTI-277 Selectively Blocks Oncogenic Ras Signaling by Inducing Cytoplasmic Accumulation of Inactive Ras-Raf Complexes

7 January 2021

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Amyloid-associated proteins α1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Lovastatin and phenylacetate inhibit the induction of nitric oxide synthase and cytokines in rat primary astrocytes, microglia, and macrophages

7 January 2021

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3-Hydroxy-3-methylglutaryl CoA reductase inhibitors up-regulate transforming growth factor-beta signaling in cultured heart cells via inhibition of geranylgeranylation of RhoA GTPase

7 January 2021

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Detection of apolipoprotein E/dimeric soluble amyloid beta complexes in Alzheimer's disease brain supernatants

7 January 2021

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Astrocytes synthesize apolipoprotein E and metabolize apolipoprotein E-containing lipoproteins

7 January 2021

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Formation of beta-amyloid protein deposits in brains of transgenic mice

7 January 2021

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Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model

7 January 2021

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A cholesterol-lowering drug reduces beta-amyloid pathology in a transgenic mouse model of Alzheimer's disease

7 January 2021

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Opposite roles of apolipoprotein E in normal brains and in Alzheimer's disease.

7 January 2021

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Apolipoprotein E and Alzheimer disease: an update on genetic and functional analyses

7 January 2021

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Apolipoprotein E distribution among different plaque types in Alzheimer's disease: implications for its role in plaque progression.

7 January 2021

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Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons

7 January 2021

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Functional aspects of polyisoprenoid protein substituents: roles in protein-protein interaction and trafficking

7 January 2021

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Apolipoprotein E epsilon4 and the risk of dementia with stroke. A population-based investigation.

7 January 2021

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Brain infarction and the clinical expression of Alzheimer disease. The Nun Study

7 January 2021

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Induction of Alzheimer-like beta-amyloid immunoreactivity in the brains of rabbits with dietary cholesterol

7 January 2021

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Coronary artery disease, hypertension, ApoE, and cholesterol: a link to Alzheimer's disease?

7 January 2021

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A simple method for organotypic cultures of nervous tissue

7 January 2021

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Expression of differential immune factors in temporal cortex and cerebellum: the role of alpha-1-antichymotrypsin, apolipoprotein E, and reactive glia in the progression of Alzheimer's disease

7 January 2021

1 reference

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Both farnesyltransferase and geranylgeranyltransferase I inhibitors are required for inhibition of oncogenic K-Ras prenylation but each alone is sufficient to suppress human tumor growth in nude mouse xenografts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903480-7

Statins selectively inhibit leukocyte function antigen-1 by binding to a novel regulatory integrin site

7 January 2021

1 reference

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Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903480-7

Isolation and characterization of apolipoproteins from murine microglia. Identification of a low density lipoprotein-like apolipoprotein J-rich but E-poor spherical particle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903480-7

10.1016/S0006-8993(02)03480-7

7 January 2021

Identifiers

DOI

1 reference

22 September 2017

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