(Q40702060)

English

Syntheses and EGFR and HER-2 kinase inhibitory activities of 4-anilinoquinoline-3-carbonitriles: analogues of three important 4-anilinoquinazolines currently undergoing clinical evaluation as therapeutic antitumor agents

scientific article published on October 2002

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scholarly article

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Europe PubMed Central

PubMed publication ID

22 September 2017

Syntheses and EGFR and HER-2 kinase inhibitory activities of 4-anilinoquinoline-3-carbonitriles: analogues of three important 4-anilinoquinazolines currently undergoing clinical evaluation as therapeutic antitumor agents (English)

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

1 reference

ChEBI release 2020-05-28

author name string

Allan Wissner

1

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

M Brawner Brawner Floyd

2

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Sridhar K Rabindran

3

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Ramaswamy Nilakantan

4

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Lee M Greenberger

5

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Ru Shen

6

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Yu-Fen Wang

7

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Hwei-Ru Tsou

8

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

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publication date

1 October 2002

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Europe PubMed Central

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22 September 2017

number of pages

5

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Bioorganic & Medicinal Chemistry Letters

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Europe PubMed Central

PubMed publication ID

22 September 2017

12

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Europe PubMed Central

PubMed publication ID

22 September 2017

20

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Europe PubMed Central

PubMed publication ID

22 September 2017

2893-2897

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Expression of epidermal growth factor receptor and proliferating cell nuclear antigen predicts response of esophageal squamous cell carcinoma to chemoradiotherapy

1 reference

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A specific inhibitor of the epidermal growth factor receptor tyrosine kinase

1 reference

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Epidermal growth factor receptor tyrosine kinase. Investigation of catalytic mechanism, structure-based searching and discovery of a potent inhibitor

1 reference

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Studies leading to the identification of ZD1839 (IRESSA): an orally active, selective epidermal growth factor receptor tyrosine kinase inhibitor targeted to the treatment of cancer

1 reference

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Phase I and pharmacologic study of OSI-774, an epidermal growth factor receptor tyrosine kinase inhibitor, in patients with advanced solid malignancies

1 reference

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Tyrosine kinase inhibitors. 17. Irreversible inhibitors of the epidermal growth factor receptor: 4-(phenylamino)quinazoline- and 4-(phenylamino)pyrido[3,2-d]pyrimidine-6-acrylamides bearing additional solubilizing functions

1 reference

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6-Substituted-4-(3-bromophenylamino)quinazolines as putative irreversible inhibitors of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor (HER-2) tyrosine kinases with enhanced antitumor activity

1 reference

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Irreversible inhibition of epidermal growth factor receptor tyrosine kinase with in vivo activity by N-[4-[(3-bromophenyl)amino]-6-quinazolinyl]-2-butynamide (CL-387,785)

1 reference

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CI-1033, a pan-erbB tyrosine kinase inhibitor

1 reference

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4-Anilino-6,7-dialkoxyquinoline-3-carbonitrile inhibitors of epidermal growth factor receptor kinase and their bioisosteric relationship to the 4-anilino-6,7-dialkoxyquinazoline inhibitors

1 reference

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Inhibitors of src tyrosine kinase: the preparation and structure-activity relationship of 4-anilino-3-cyanoquinolines and 4-anilinoquinazolines

1 reference

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Synthesis and Src kinase inhibitory activity of a series of 4-phenylamino-3-quinolinecarbonitriles

1 reference

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Optimization of 4-phenylamino-3-quinolinecarbonitriles as potent inhibitors of Src kinase activity

1 reference

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Synthesis and structure-activity relationships of 3-cyano-4-(phenoxyanilino)quinolines as MEK (MAPKK) inhibitors

1 reference

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based on heuristic

inferred from DOI database lookup

MEK (MAPKK) inhibitors. Part 2: structure-activity relationships of 4-anilino-3-cyano-6,7-dialkoxyquinolines

1 reference

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Combinatorial chemoprevention of intestinal neoplasia

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Binding mode of the 4-anilinoquinazoline class of protein kinase inhibitor: X-ray crystallographic studies of 4-anilinoquinazolines bound to cyclin-dependent kinase 2 and p38 kinase

1 reference

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7 January 2021

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Structure-based design of potent inhibitors of scytalone dehydratase: displacement of a water molecule from the active site

1 reference

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7 January 2021

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Identifiers

10.1016/S0960-894X(02)00598-X

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

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