(Q40703241)

22 September 2017

title

Proteasome inhibitors reconstitute the presentation of cytotoxic T-cell epitopes in Epstein-Barr virus-associated tumors (English)

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22 September 2017

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22 September 2017

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22 September 2017

Simona Vertuani

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22 September 2017

language of work or name

English

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publication date

1 October 2002

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International Journal of Cancer

22 September 2017

published in

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22 September 2017

volume

101

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22 September 2017

issue

6

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22 September 2017

page(s)

532-538

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Mechanisms of MHC class I--restricted antigen processing

22 September 2017

cites work

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Degradation of cell proteins and the generation of MHC class I-presented peptides

21 January 2018

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The 26S proteasome: a molecular machine designed for controlled proteolysis

21 January 2018

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Proteasome inhibitors: valuable new tools for cell biologists

21 January 2018

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Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

21 January 2018

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Modulation of proteasomal activity required for the generation of a cytotoxic T lymphocyte-defined peptide derived from the tumor antigen MAGE-3.

21 January 2018

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The selective proteasome inhibitors lactacystin and epoxomicin can be used to either up- or down-regulate antigen presentation at nontoxic doses

21 January 2018

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Antigen-processing machinery breakdown and tumor growth

21 January 2018

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Human cytotoxic T lymphocyte responses to Epstein-Barr virus infection

21 January 2018

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Down-regulation of class I HLA antigens and of the Epstein-Barr virus-encoded latent membrane protein in Burkitt lymphoma lines

21 January 2018

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Defective presentation of MHC class I-restricted cytotoxic T-cell epitopes in Burkitt's lymphoma cells

21 January 2018

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c-myc overexpression activates alternative pathways for intracellular proteolysis in lymphoma cells.

21 January 2018

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Selective amino acid substitutions of a subdominant Epstein-Barr virus LMP2-derived epitope increase HLA/peptide complex stability and immunogenicity: implications for immunotherapy of Epstein-Barr virus-associated malignancies

21 January 2018

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Gamma-interferon and expression of MHC genes regulate peptide hydrolysis by proteasomes

21 January 2018

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Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin

21 January 2018

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Covalent modification of the active site threonine of proteasomal beta subunits and the Escherichia coli homolog HslV by a new class of inhibitors

21 January 2018

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Proteasome inhibition by the natural products epoxomicin and dihydroeponemycin: insights into specificity and potency.

21 January 2018

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Total synthesis of the potent proteasome inhibitor epoxomicin: a useful tool for understanding proteasome biology.

21 January 2018

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Interleukin-1 beta converting enzyme.

21 January 2018

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Low-Molecular-Weight Enzyme Inhibitors of Microbial Origin

21 January 2018

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Sequential cleavage by metallopeptidases and proteasomes is involved in processing HIV-1 ENV epitope for endogenous MHC class I antigen presentation

21 January 2018

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A giant protease with potential to substitute for some functions of the proteasome

21 January 2018

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Processing of a multiple membrane spanning Epstein-Barr virus protein for CD8(+) T cell recognition reveals a proteasome-dependent, transporter associated with antigen processing-independent pathway

21 January 2018

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Inactivation of a defined active site in the mouse 20S proteasome complex enhances major histocompatibility complex class I antigen presentation of a murine cytomegalovirus protein.

21 January 2018

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Processing of some antigens by the standard proteasome but not by the immunoproteasome results in poor presentation by dendritic cells

21 January 2018

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Immunoproteasomes shape immunodominance hierarchies of antiviral CD8(+) T cells at the levels of T cell repertoire and presentation of viral antigens.

21 January 2018

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Structural basis for the activation of 20S proteasomes by 11S regulators

21 January 2018

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The axial channel of the proteasome core particle is gated by the Rpt2 ATPase and controls both substrate entry and product release

21 January 2018

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Class I major histocompatibility complex-restricted cytotoxic T lymphocytes specific for Epstein-Barr virus (EBV)-transformed B lymphoblastoid cell lines against which they were raised

21 January 2018

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Activation of epitope-specific memory cytotoxic T lymphocyte responses by synthetic peptides.

21 January 2018

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Inhibition of antigen processing by the internal repeat region of the Epstein-Barr virus nuclear antigen-1.

21 January 2018

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MHC-linked LMP gene products specifically alter peptidase activities of the proteasome

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/IJC.10653

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22 September 2017

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