(Q40704467)

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The human reduced folate carrier gene is regulated by the AP2 and sp1 transcription factor families and a functional 61-base pair polymorphism

scientific article published on 12 September 2002

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Europe PubMed Central

PubMed publication ID

22 September 2017

The human reduced folate carrier gene is regulated by the AP2 and sp1 transcription factor families and a functional 61-base pair polymorphism (English)

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

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Johnathan R Whetstine

1

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Teah L Witt

2

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Larry H Matherly

3

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Europe PubMed Central

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22 September 2017

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publication date

12 September 2002

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Europe PubMed Central

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22 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

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22 September 2017

277

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Europe PubMed Central

PubMed publication ID

22 September 2017

46

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

43873-43880

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

The cellular pharmacology of methotrexate

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21 January 2018

Molecular and cellular biology of the human reduced folate carrier

1 reference

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21 January 2018

A structurally altered human reduced folate carrier with increased folic acid transport mediates a novel mechanism of antifolate resistance.

1 reference

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21 January 2018

Impaired membrane transport in methotrexate-resistant CCRF-CEM cells involves early translation termination and increased turnover of a mutant reduced folate carrier.

1 reference

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21 January 2018

Methotrexate pharmacology and resistance in childhood acute lymphoblastic leukemia

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Homocysteine and cardiovascular disease

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Folic acid and the prevention of birth defects

1 reference

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21 January 2018

CSF-folate levels are decreased in late-onset AD patients

1 reference

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21 January 2018

The human reduced folate carrier gene is ubiquitously and differentially expressed in normal human tissues: identification of seven non-coding exons and characterization of a novel promoter

1 reference

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21 January 2018

Tissue-specific promoters of the alpha human folate receptor gene yield transcripts with divergent 5' leader sequences and different translational efficiencies

1 reference

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21 January 2018

The divergent 5' termini of the alpha human folate receptor (hFR) mRNAs originate from two tissue-specific promoters and alternative splicing: characterization of the alpha hFR gene structure

1 reference

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21 January 2018

Purification and properties of human cytosolic folylpoly-gamma-glutamate synthetase and organization, localization, and differential splicing of its gene

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21 January 2018

Organization and alternate splicing of the murine folylpolyglutamate synthetase gene. Different splice variants in L1210 cells encode mitochondrial or cytosolic forms of the enzyme

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21 January 2018

Expression patterns of the multiple transcripts from the folylpolyglutamate synthetase gene in human leukemias and normal differentiated tissues

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21 January 2018

A mutation in the 5' untranslated region increases stability of norA mRNA, encoding a multidrug resistance transporter of Staphylococcus aureus

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21 January 2018

The basal promoters for the human reduced folate carrier gene are regulated by a GC-box and a cAMP-response element/AP-1-like element. Basis for tissue-specific gene expression

1 reference

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21 January 2018

Transcript heterogeneity of the human reduced folate carrier results from the use of multiple promoters and variable splicing of alternative upstream exons

1 reference

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21 January 2018

Gene splicing by overlap extension: tailor-made genes using the polymerase chain reaction

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21 January 2018

Characterization of the DNA-binding properties of the myeloid zinc finger protein MZF1: two independent DNA-binding domains recognize two DNA consensus sequences with a common G-rich core

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21 January 2018

The adenovirus major late transcription factor USF is a member of the helix-loop-helix group of regulatory proteins and binds to DNA as a dimer

1 reference

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21 January 2018

Recombinant 43-kDa USF binds to DNA and activates transcription in a manner indistinguishable from that of natural 43/44-kDa USF.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208296200

21 January 2018

MatInd and MatInspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208296200

21 January 2018

A tale of three fingers: the family of mammalian Sp/XKLF transcription factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208296200

21 January 2018

The Sp-family of transcription factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208296200

21 January 2018

Sp3 encodes multiple proteins that differ in their capacity to stimulate or repress transcription

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208296200

21 January 2018

Cloning by recognition site screening of two novel GT box binding proteins: a family of Sp1 related genes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208296200

21 January 2018

Sp3 is a transcriptional activator of the human alpha2(I) collagen gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208296200

21 January 2018

Modulation of human alpha1(I) procollagen gene activity by interaction with Sp1 and Sp3 transcription factors in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208296200

21 January 2018

Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motif

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208296200

21 January 2018

Synergistic activation by the glutamine-rich domains of human transcription factor Sp1

1 reference

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21 January 2018

Different activation domains of Sp1 govern formation of multimers and mediate transcriptional synergism

1 reference

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21 January 2018

Sp3 mediates transcriptional activation of the leukocyte integrin genes CD11C and CD11B and cooperates with c-Jun to activate CD11C.

1 reference

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21 January 2018

A critical role for cAMP response element-binding protein (CREB) as a Co-activator in sterol-regulated transcription of 3-hydroxy-3-methylglutaryl coenzyme A synthase promoter

1 reference

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21 January 2018

Regulatory roles of AP-2 transcription factors in vertebrate development, apoptosis and cell-cycle control

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21 January 2018

Transcriptional regulation of the human manganese superoxide dismutase gene: the role of specificity protein 1 (Sp1) and activating protein-2 (AP-2).

1 reference

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21 January 2018

Ap-2 and Ikaros regulate transcription of human placental leucine aminopeptidase/oxytocinase gene

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21 January 2018

Biological and clinical implications of the MTHFR C677T polymorphism

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21 January 2018

Thymidylate synthase gene polymorphism determines response and toxicity of 5-FU chemotherapy

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21 January 2018

Structural organization of the human reduced folate carrier gene: evidence for 5' heterogeneity in lymphoblast mRNA.

1 reference

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21 January 2018

Isolation of human cDNAs that restore methotrexate sensitivity and reduced folate carrier activity in methotrexate transport-defective Chinese hamster ovary cells

1 reference

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21 January 2018

Gene splicing by overlap extension: tailor-made genes using the polymerase chain reaction. BioTechniques 8(5):528-535 (November 1990).

1 reference

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21 January 2018

Human K562 transfectants expressing high levels of reduced folate carrier but exhibiting low transport activity

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21 January 2018

Post-transcriptional regulation of rat CYP2E1 expression: role of CYP2E1 mRNA untranslated regions in control of translational efficiency and message stability

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The inhibitory effect of the 5' untranslated region of muscle acylphosphatase mRNA on protein expression is relieved during cell differentiation

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21 January 2018

Both the cyclic AMP response element and the activator protein 2 binding site mediate basal and cyclic AMP-induced transcription from the dominant promoter of the rat alpha 1B-adrenergic receptor gene in DDT1MF-2 cells.

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21 January 2018

Identifiers

10.1074/JBC.M208296200

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

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