(Q40712152)

English

Dual inhibition of focal adhesion kinase and epidermal growth factor receptor pathways cooperatively induces death receptor-mediated apoptosis in human breast cancer cells

scientific article published on 7 August 2002

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scholarly article

1 reference

Europe PubMed Central

23 September 2017

Dual inhibition of focal adhesion kinase and epidermal growth factor receptor pathways cooperatively induces death receptor-mediated apoptosis in human breast cancer cells (English)

1 reference

Europe PubMed Central

23 September 2017

author name string

Vita Golubovskaya

1

1 reference

Europe PubMed Central

23 September 2017

Lucia Beviglia

2

1 reference

Europe PubMed Central

23 September 2017

Li-Hui Xu

3

1 reference

Europe PubMed Central

23 September 2017

H Shelton Earp

4

1 reference

Europe PubMed Central

23 September 2017

Rolf Craven

5

1 reference

Europe PubMed Central

23 September 2017

William Cance

6

1 reference

Europe PubMed Central

23 September 2017

language of work or name

0 references

publication date

7 August 2002

1 reference

Europe PubMed Central

23 September 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

23 September 2017

277

1 reference

Europe PubMed Central

23 September 2017

38978-38987

1 reference

Europe PubMed Central

23 September 2017

41

1 reference

Europe PubMed Central

23 September 2017

The focal adhesion kinase suppresses transformation-associated, anchorage-independent apoptosis in human breast cancer cells. Involvement of death receptor-related signaling pathways.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

Signaling through focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

Focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

Monoclonal antibodies to individual tyrosine-phosphorylated protein substrates of oncogene-encoded tyrosine kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

Stable association of pp60src and pp59fyn with the focal adhesion-associated protein tyrosine kinase, pp125FAK.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

Paxillin, a tyrosine phosphorylated focal adhesion-associated protein binds to the carboxyl terminal domain of focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

Signaling through focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

Autonomous expression of a noncatalytic domain of the focal adhesion-associated protein tyrosine kinase pp125FAK

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

Regulated expression of focal adhesion kinase-related nonkinase, the autonomously expressed C-terminal domain of focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

Inhibition of cell spreading by expression of the C-terminal domain of focal adhesion kinase (FAK) is rescued by coexpression of Src or catalytically inactive FAK: a role for paxillin tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

Expression of growth factor receptors, the focal adhesion kinase, and other tyrosine kinases in human soft tissue tumors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

Extracellular matrix survival signals transduced by focal adhesion kinase suppress p53-mediated apoptosis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

Suppression of chemically induced apoptosis but not necrosis of renal proximal tubular epithelial (LLC-PK1) cells by focal adhesion kinase (FAK). Role of FAK in maintaining focal adhesion organization after acute renal cell injury

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

Control of adhesion-dependent cell survival by focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

Anti-apoptotic role of focal adhesion kinase (FAK). Induction of inhibitor-of-apoptosis proteins and apoptosis suppression by the overexpression of FAK in a human leukemic cell line, HL-60.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

Caspases cleave focal adhesion kinase during apoptosis to generate a FRNK-like polypeptide.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

Epidermal growth factor-induced tumor cell invasion and metastasis initiated by dephosphorylation and downregulation of focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

FAK integrates growth-factor and integrin signals to promote cell migration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

Evidence that autophosphorylation of solubilized receptors for epidermal growth factor is mediated by intermolecular cross-phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

Cell signaling by receptor tyrosine kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

Oncogenic kinase signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

Heterodimerization and functional interaction between EGF receptor family members: a new signaling paradigm with implications for breast cancer research

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

Epidermal growth factor receptor biology (IMC-C225).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

EGF-receptors in human normal and pathological thyroid tissue

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

Expression of epidermal growth factor and androgen receptors in ovarian cancer.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

Epidermal growth factor, transforming growth factor-alpha, and epidermal growth factor receptor content in normal and carcinomatous gastric and colonic tissue.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

Endocytosis deficiency of epidermal growth factor (EGF) receptor-ErbB2 heterodimers in response to EGF stimulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

A mechanism for regulation of the adhesion-associated proteintyrosine kinase pp125FAK.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

FAK is the upstream signal protein of the phosphatidylinositol 3-kinase-Akt survival pathway in hydrogen peroxide-induced apoptosis of a human glioblastoma cell line

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

Elevated epidermal growth factor receptor gene copy number and expression in a squamous carcinoma cell line

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

Antisense oligonucleotides to the epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

Fibroblast growth factor-2 suppression of tumor necrosis factor alpha-mediated apoptosis requires Ras and the activation of mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

Activation of extracellular signal-regulated kinase by ultraviolet is mediated through Src-dependent epidermal growth factor receptor phosphorylation. Its implication in an anti-apoptotic function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

Epidermal growth factor receptor-dependent control of keratinocyte survival and Bcl-xL expression through a MEK-dependent pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

Activation of the Ras/mitogen-activated protein kinase pathway by kinase-defective epidermal growth factor receptors results in cell survival but not proliferation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

Epidermal growth factor protects epithelial cells against Fas-induced apoptosis. Requirement for Akt activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

The alpha5beta1 integrin selectively enhances epidermal growth factor signaling to the phosphatidylinositol-3-kinase/Akt pathway in intestinal epithelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

The cleavage of Akt/protein kinase B by death receptor signaling is an important event in detachment-induced apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

Epidermal growth factor receptors in breast cancer: Association with early relapse and death, poor response to hormones and interactions with neu

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

Expression of focal adhesion kinase gene and invasive cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

The EGF receptor: a nexus for trafficking and signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

Epidermal growth factor receptor-dependent Akt activation by oxidative stress enhances cell survival

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205002200

21 January 2018

Identifiers

10.1074/JBC.M205002200

1 reference

Europe PubMed Central

23 September 2017

1 reference

Europe PubMed Central

23 September 2017

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