(Q40714830)

23 September 2017

title

A novel MPL point mutation resulting in thrombopoietin-independent activation (English)

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23 September 2017

M Abe

1

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23 September 2017

K Suzuki

2

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23 September 2017

O Inagaki

3

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23 September 2017

S Sassa

4

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23 September 2017

H Shikama

5

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23 September 2017

publication date

1 August 2002

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23 September 2017

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23 September 2017

volume

16

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23 September 2017

issue

8

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23 September 2017

page(s)

1500-1506

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Control of thrombocytopoiesis: current state of the art.

23 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402554

7 January 2021

Thrombopoietin: the primary regulator of platelet production [see comments]

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402554

7 January 2021

Thrombopoietin, the Mp1 ligand, is essential for full megakaryocyte development

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402554

7 January 2021

Thrombocytopenia in c-mpl-deficient mice

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402554

7 January 2021

The c-Mpl ligand (thrombopoietin) stimulates tyrosine phosphorylation of Jak2, Shc, and c-Mpl

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402554

7 January 2021

TPO/c-mpl ligand induces tyrosine phosphorylation of multiple cellular proteins including proto-oncogene products, Vav and c-Cbl, and Ras signaling molecules

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402554

7 January 2021

Thrombopoietin signal transduction requires functional JAK2, not TYK2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402554

7 January 2021

The thrombopoietin receptor can mediate proliferation without activation of the Jak-STAT pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402554

7 January 2021

Control of thrombopoietin-induced megakaryocytic differentiation by the mitogen-activated protein kinase pathway

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402554

7 January 2021

Protein kinase C and c-myc gene activation pathways in thrombopoietin signal transduction.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402554

7 January 2021

Thrombopoietin induces activation of the phosphatidylinositol-3' kinase pathway and formation of a complex containing p85PI3K and the protooncoprotein p120CBL.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402554

7 January 2021

Thrombopoietin-induced conformational change in p53 lies downstream of the p44/p42 mitogen activated protein kinase cascade in the human growth factor-dependent cell line M07e

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402554

7 January 2021

Dissecting the thrombopoietin receptor: functional elements of the Mpl cytoplasmic domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402554

7 January 2021

Role of the distal half of the c-Mpl intracellular domain in control of platelet production by thrombopoietin in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402554

7 January 2021

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402554

7 January 2021

Interleukin 3-dependent survival by the Akt protein kinase

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402554

7 January 2021

Interleukin-6 inhibits transforming growth factor-beta-induced apoptosis through the phosphatidylinositol 3-kinase/Akt and signal transducers and activators of transcription 3 pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402554

7 January 2021

Dissociation of apoptosis from proliferation, protein kinase B activation, and BAD phosphorylation in interleukin-3-mediated phosphoinositide 3-kinase signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402554

7 January 2021

Thrombopoietin induces phosphoinositol 3-kinase activation through SHP2, Gab, and insulin receptor substrate proteins in BAF3 cells and primary murine megakaryocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402554

7 January 2021

Point mutation in the exoplasmic domain of the erythropoietin receptor resulting in hormone-independent activation and tumorigenicity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402554

7 January 2021

Surrogate thrombopoietin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402554

7 January 2021

Distinct regulation of glucose transport by interleukin-3 and oncogenes in a murine bone marrow-derived cell line.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402554

7 January 2021

Efficiency of signalling through cytokine receptors depends critically on receptor orientation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402554

7 January 2021

Membrane localization is not required for Mpl function in normal hematopoietic cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402554

7 January 2021

A structure-function analysis of serine/threonine phosphorylation of the thrombopoietin receptor, c-Mpl

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402554

7 January 2021

Constitutively Activated Jak-STAT Pathway in T Cells Transformed with HTLV-I

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402554

7 January 2021

Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402554

7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2402554

1 reference

Dimensions Publication ID

23 September 2017

1011133818

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1 reference