(Q40720173)

23 September 2017

Hydroxyurea significantly enhances tumor growth delay in vivo with herpes simplex virus thymidine kinase/ganciclovir gene therapy (English)

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23 September 2017

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Boucher PD

1

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23 September 2017

Ostruszka LJ

series ordinal

2

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23 September 2017

Murphy PJ

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3

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23 September 2017

Shewach DS

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4

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23 September 2017

1 August 2002

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23 September 2017

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23 September 2017

9

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23 September 2017

15

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23 September 2017

1023-1030

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https://scigraph.springernature.com/pub.10.1038/sj.gt.3301730

23 September 2017

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cites work

Regression of established macroscopic liver metastases after in situ transduction of a suicide gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301730

Retrovirally transmitted gene therapy for gastric carcinoma using herpes simplex virus thymidine kinase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301730

Gene therapy for cancer: what have we done and where are we going?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301730

Bystander effects of different enzyme-prodrug systems for cancer gene therapy depend on different pathways for intercellular transfer of toxic metabolites, a factor that will govern clinical choice of appropriate regimes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301730

Differential ganciclovir-mediated cytotoxicity and bystander killing in human colon carcinoma cell lines expressing herpes simplex virus thymidine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301730

In vitro evidence that metabolic cooperation is responsible for the bystander effect observed with HSV tk retroviral gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301730

The bystander effect in the HSVtk/ganciclovir system and its relationship to gap junctional communication

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301730

Mechanism of 'bystander effect' killing in the herpes simplex thymidine kinase gene therapy model of cancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301730

Variable efficiency of the thymidine kinase/ganciclovir system in human glioblastoma cell lines: implications for gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301730

Lack of bystander killing in herpes simplex virus thymidine kinase-transduced colon cell lines due to deficient connexin43 gap junction formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301730

Intercellular communication mediates the bystander effect during herpes simplex thymidine kinase/ganciclovir-based gene therapy of human gastrointestinal tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301730

Adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir gene therapy in patients with localized malignancy: results of a phase I clinical trial in malignant mesothelioma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301730

Mechanism of DNA polymerase alpha inhibition by aphidicolin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301730

Pharmacokinetics and pharmacodynamics of hydroxyurea

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301730

In vivo and in vitro comparison of the short-term hematopoietic toxicity between hydroxyurea and trimidox or didox, novel ribonucleotide reductase inhibitors with potential anti-HIV-1 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301730

Effects of perturbations of pools of deoxyribonucleoside triphosphates on expression of ribonucleotide reductase, a G1/S transition state enzyme, in p53-mutated cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301730

A method for the synchronization of cultured cells with aphidicolin: application to the large-scale synchronization of L1210 cells and the study of the cell cycle regulation of thymidylate synthase and dihydrofolate reductase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301730

Cell-cell communication in carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301730

Bystander killing of cancer cells by herpes simplex virus thymidine kinase gene is mediated by connexins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301730

Transfer of the bacterial gene for cytosine deaminase to mammalian cells confers lethal sensitivity to 5-fluorocytosine: a negative selection system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301730

Glioma cells transduced with an Escherichia coli CD/HSV-1 TK fusion gene exhibit enhanced metabolic suicide and radiosensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301730

Synergistic anticancer effects of ganciclovir/thymidine kinase and 5-fluorocytosine/cytosine deaminase gene therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301730

Analysis of tumor growth curves

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301730

Acyclic guanosine analogs inhibit DNA polymerases alpha, delta, and epsilon with very different potencies and have unique mechanisms of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301730

7 January 2021

Pharmacokinetics of hydroxyurea in nude mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301730

7 January 2021

Hydroxyurea: effects on deoxyribonucleotide pool sizes correlated with effects on DNA repair in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301730

7 January 2021

Estimation of liver tumor volume using different formulas - an experimental study in rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301730

7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3301730

1 reference

Dimensions Publication ID

23 September 2017

0 references

1 reference