(Q45885920)

17 December 2017

title

Synergistic anticancer effects of ganciclovir/thymidine kinase and 5-fluorocytosine/cytosine deaminase gene therapies (English)

1 reference

17 December 2017

main subject

cytosine

0 references

author

Xandra O. Breakefield

4

object named as

Breakefield XO

1 reference

17 December 2017

author name string

Aghi M

1

1 reference

17 December 2017

Kramm CM

2

1 reference

17 December 2017

Chou TC

3

1 reference

17 December 2017

Chiocca EA

5

1 reference

17 December 2017

language of work or name

English

0 references

publication date

1 March 1998

1 reference

17 December 2017

Journal of the National Cancer Institute

published in

1 reference

17 December 2017

volume

90

1 reference

17 December 2017

page(s)

370-380

1 reference

17 December 2017

issue

5

1 reference

17 December 2017

Gene therapy for cancer: what have we done and where are we going?

cites work

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F90.5.370

Transfer of the bacterial gene for cytosine deaminase to mammalian cells confers lethal sensitivity to 5-fluorocytosine: a negative selection system

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F90.5.370

Ganciclovir. A review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy in cytomegalovirus infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F90.5.370

Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F90.5.370

Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F90.5.370

Production of high-titer helper-free retroviruses by transient transfection

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F90.5.370

Derivation and properties of Michaelis-Menten type and Hill type equations for reference ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F90.5.370

Gene therapy of malignant brain tumors: a rat glioma line bearing the herpes simplex virus type 1-thymidine kinase gene and wild type retrovirus kills other tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F90.5.370

Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene: significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F90.5.370

Modulation of growth and proliferation in squamous cell carcinoma by retinoic acid: a rationale for combination therapy with chemotherapeutic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F90.5.370

Schedule-dependent synergism of taxol or taxotere with edatrexate against human breast cancer cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F90.5.370

Inhibitors of thymidylate synthase and dihydrofolate reductase potentiate the antiviral effect of acyclovir

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F90.5.370

Intracellular Pools of Thymidine Reduce the Antiviral Action of Acyclovir

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F90.5.370

Ganciclovir. An update of its therapeutic use in cytomegalovirus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F90.5.370

A virus-specific thymidine kinase in BHK-21 cells infected with herpes simplex virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F90.5.370

Creation of drug-specific herpes simplex virus type 1 thymidine kinase mutants for gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F90.5.370

Expression of the bacterial nitroreductase enzyme in mammalian cells renders them selectively sensitive to killing by the prodrug CB1954.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F90.5.370

Bystander effects of different enzyme-prodrug systems for cancer gene therapy depend on different pathways for intercellular transfer of toxic metabolites, a factor that will govern clinical choice of appropriate regimes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F90.5.370

Retrovirus-mediated wild-type p53 gene transfer to tumors of patients with lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F90.5.370

Glioma cells transduced with an Escherichia coli CD/HSV-1 TK fusion gene exhibit enhanced metabolic suicide and radiosensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F90.5.370

Aphidicolin prevents mitotic cell division by interfering with the activity of DNA polymerase-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F90.5.370

21 January 2018

Identifiers

DOI

10.1093/JNCI/90.5.370

1 reference

17 December 2017

PubMed ID

9498487

1 reference

17 December 2017