(Q40722094)

23 September 2017

title

Oxygen-sensitive enzyme-prodrug gene therapy for the eradication of radiation-resistant solid tumours (English)

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Adaptive radiation therapy

23 September 2017

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author

Adam Patterson

1

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23 September 2017

11

I J Stratford

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23 September 2017

2

K J Williams

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23 September 2017

R L Cowen

3

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23 September 2017

M Jaffar

4

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23 September 2017

B A Telfer

5

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23 September 2017

M Saunders

6

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23 September 2017

R Airley

7

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23 September 2017

D Honess

8

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23 September 2017

A J van der Kogel

9

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23 September 2017

C R Wolf

10

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23 September 2017

publication date

1 July 2002

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23 September 2017

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23 September 2017

volume

9

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23 September 2017

issue

14

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23 September 2017

page(s)

946-954

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https://scigraph.springernature.com/pub.10.1038/sj.gt.3301702

23 September 2017

exact match

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cites work

Hypoxia and drug resistance

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301702

Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neck

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301702

Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301702

Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301702

Inducible operation of the erythropoietin 3' enhancer in multiple cell lines: evidence for a widespread oxygen-sensing mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301702

Overexpression of human NADPH:cytochrome c (P450) reductase confers enhanced sensitivity to both tirapazamine (SR 4233) and RSU 1069

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301702

Hypoxia and mitochondrial inhibitors regulate expression of glucose transporter-1 via distinct Cis-acting sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301702

A phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301702

Electroporation in ‘intracellular’ buffer increases cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301702

Optical sensor-based oxygen tension measurements correspond with hypoxia marker binding in three human tumor xenograft lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301702

Targeting gene expression to hypoxic tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301702

Oxygen distribution in squamous cell carcinoma metastases and its relationship to outcome of radiation therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301702

7 January 2021

Oxygen tension distributions are sufficient to explain the local response of human breast tumors treated with radiation alone

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301702

7 January 2021

Effect of etoposide, carmustine, vincristine, 5-fluorouracil, or methotrexate on radiobiologically oxic and hypoxic cells in a C3H mouse mammary carcinoma in situ

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301702

7 January 2021

RSU 1069, a 2-nitroimidazole containing an alkylating group: high efficiency as a radio- and chemosensitizer in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301702

7 January 2021

RSU 1069, a nitroimidazole containing an aziridine group. Bioreduction greatly increases cytotoxicity under hypoxic conditions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301702

7 January 2021

Synthesis and evaluation of alpha-[[(2-haloethyl)amino]methyl]-2- nitro-1H-imidazole-1-ethanols as prodrugs of alpha-[(1-aziridinyl)methyl]-2- nitro-1H-imidazole-1-ethanol (RSU-1069) and its analogues which are radiosensitizers and bioreductively ac

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301702

7 January 2021

Comparison between the comet assay and the oxygen microelectrode for measurement of tumor hypoxia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301702

7 January 2021

Comparisons among pimonidazole binding, oxygen electrode measurements, and radiation response in C3H mouse tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301702

7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3301702

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Dimensions Publication ID

23 September 2017

1049484786

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1 reference