(Q40723935)

23 September 2017

Several PATCHED1 missense mutations display activity in patched1-deficient fibroblasts (English)

1 reference

23 September 2017

Evans C Bailey

1

1 reference

23 September 2017

Ljiljana Milenkovic

2

1 reference

23 September 2017

Matthew P Scott

3

1 reference

23 September 2017

James F Collawn

4

1 reference

23 September 2017

Ronald L Johnson

5

1 reference

23 September 2017

language of work or name

English

0 references

publication date

18 June 2002

1 reference

Journal of Biological Chemistry

23 September 2017

1 reference

23 September 2017

277

1 reference

23 September 2017

37

1 reference

23 September 2017

33632-33640

1 reference

Hedgehog and patched in neural development and disease

23 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

Human homolog of patched, a candidate gene for the basal cell nevus syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

The role of the human homologue of Drosophila patched in sporadic basal cell carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

Transducing Hedgehog: the story so far

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

The world according to hedgehog

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

The Hedgehog and Wnt signalling pathways in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

A protein with several possible membrane-spanning domains encoded by the Drosophila segment polarity gene patched

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

The Drosophila patched gene encodes a putative membrane protein required for segmental patterning

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

Sonic hedgehog protein signals not as a hydrolytic enzyme but as an apparent ligand for patched

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

Sonic hedgehog differentially regulates expression of GLI and GLI3 during limb development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

Control of cell pattern in the neural tube by the zinc finger transcription factor and oncogene Gli-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

smoothened encodes a receptor-like serpentine protein required for hedgehog signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

The Drosophila smoothened gene encodes a seven-pass membrane protein, a putative receptor for the hedgehog signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

The GLI gene is a member of the Kruppel family of zinc finger proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

GLI3 encodes a 190-kilodalton protein with multiple regions of GLI similarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

Cloning and characterization of the segment polarity gene cubitus interruptus Dominant of Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

Transcriptional activation of hedgehog target genes in Drosophila is mediated directly by the cubitus interruptus protein, a member of the GLI family of zinc finger DNA-binding proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

Rhabdomyosarcomas and radiation hypersensitivity in a mouse model of Gorlin syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

Altered neural cell fates and medulloblastoma in mouse patched mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

Ultraviolet and ionizing radiation enhance the growth of BCCs and trichoblastomas in patched heterozygous knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

Production of high-titer helper-free retroviruses by transient transfection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

Stochastic, stage-specific mechanisms account for the variegation of a human globin transgene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

A mouse model of greig cephalopolysyndactyly syndrome: the extra-toesJ mutation contains an intragenic deletion of the Gli3 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

Activating Smoothened mutations in sporadic basal-cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

Characterization of two patched receptors for the vertebrate hedgehog protein family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

Characterisation of a second patched gene in the zebrafish Danio rerio and the differential response of patched genes to Hedgehog signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

Overlapping and non-overlapping Ptch2 expression with Shh during mouse embryogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

In vivo functions of the patched protein: requirement of the C terminus for target gene inactivation but not Hedgehog sequestration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

Gorlin syndrome: identification of 4 novel germ-line mutations of the human patched (PTCH) gene. Mutations in brief no. 137. Online

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

High levels of patched gene mutations in basal-cell carcinomas from patients with xeroderma pigmentosum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

Biochemical evidence that patched is the Hedgehog receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

Assembly of asparagine-linked oligosaccharides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

Identification of mutations in the human PATCHED gene in sporadic basal cell carcinomas and in patients with the basal cell nevus syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

Generation of mammalian cells stably expressing multiple genes at predetermined levels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

Induction of basal cell carcinoma features in transgenic human skin expressing Sonic Hedgehog

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

Mutations in the human homologue of the Drosophila patched gene in esophageal squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

The hedgehog signalling pathway in tumorigenesis and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

Mutations in the sterol-sensing domain of Patched suggest a role for vesicular trafficking in Smoothened regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

Sonic hedgehog and Fgf-4 act through a signaling cascade and feedback loop to integrate growth and patterning of the developing limb bud

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

Variation of risks of breast and ovarian cancer associated with different germline mutations of the BRCA2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202203200

21 January 2018

Identifiers

DOI

10.1074/JBC.M202203200

1 reference

23 September 2017

1 reference