(Q28189485)

7 January 2021

Linking colorectal cancer to Wnt signaling

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7 January 2021

Transducing Hedgehog: the story so far

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7 January 2021

Hedgehog and patched in neural development and disease

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7 January 2021

More surprises in the Hedgehog signaling pathway

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7 January 2021

Secretion and localized transcription suggest a role in positional signaling for products of the segmentation gene hedgehog

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7 January 2021

Transducing the hedgehog signal

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7 January 2021

Cholesterol modification of hedgehog signaling proteins in animal development

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7 January 2021

Identification of a palmitic acid-modified form of human Sonic hedgehog

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7 January 2021

Functional binding of secreted molecules to heparan sulfate proteoglycans in Drosophila

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7 January 2021

Dispatched, a novel sterol-sensing domain protein dedicated to the release of cholesterol-modified hedgehog from signaling cells

1 reference

7 January 2021

Transmembrane molecular pump activity of Niemann-Pick C1 protein

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7 January 2021

The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog

1 reference

7 January 2021

Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened

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7 January 2021

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

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7 January 2021

Proteolysis That Is Inhibited by Hedgehog Targets Cubitus interruptus Protein to the Nucleus and Converts It to a Repressor

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7 January 2021

Hedgehog Elicits Signal Transduction by Means of a Large Complex Containing the Kinesin-Related Protein Costal2

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7 January 2021

Nuclear trafficking of Cubitus interruptus in the transcriptional regulation of Hedgehog target gene expression

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7 January 2021

Feedback control of intercellular signalling in development

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7 January 2021

WNT signalling molecules act in axis formation in the diploblastic metazoan Hydra.

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7 January 2021

An LDL-receptor-related protein mediates Wnt signalling in mice

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7 January 2021

A new member of the frizzled family from Drosophila functions as a Wingless receptor

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7 January 2021

Functional interaction of beta-catenin with the transcription factor LEF-1

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7 January 2021

Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome

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7 January 2021

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

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7 January 2021

Identification of c-MYC as a target of the APC pathway

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7 January 2021

Human homolog of patched, a candidate gene for the basal cell nevus syndrome

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7 January 2021

Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome

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7 January 2021

Activating Smoothened mutations in sporadic basal-cell carcinoma

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7 January 2021

A frequent activated smoothened mutation in sporadic basal cell carcinomas

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7 January 2021

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7 January 2021

TGFbeta signaling in growth control, cancer, and heritable disorders

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7 January 2021

Extracellular matrix-associated transforming growth factor-beta: role in cancer cell growth and invasion.

1 reference

7 January 2021

The Hallmarks of Cancer

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7 January 2021

Frequent clones of p53-mutated keratinocytes in normal human skin

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7 January 2021

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

1 reference

7 January 2021

A niche maintaining germ line stem cells in the Drosophila ovary

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7 January 2021

Hedgehog acts as a somatic stem cell factor in the Drosophila ovary

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7 January 2021

Stem cells: a new lease on life

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7 January 2021

Lessons from hereditary colorectal cancer

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7 January 2021

Gut instincts: thoughts on intestinal epithelial stem cells

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7 January 2021

Post-irradiation somatic mutation and clonal stabilisation time in the human colon

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7 January 2021

Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4

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7 January 2021

The Min (multiple intestinal neoplasia) mutation: its effect on gut epithelial cell differentiation and interaction with a modifier system

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7 January 2021

Embryonic precursor cells from the rhombic lip are specified to a cerebellar granule neuron identity

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7 January 2021

The developmental biology of brain tumors.

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7 January 2021

Sonic hedgehog promotes G(1) cyclin expression and sustained cell cycle progression in mammalian neuronal precursors

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7 January 2021

A role for p27/Kip1 in the control of cerebellar granule cell precursor proliferation.

1 reference

7 January 2021

Cell-cycle inhibitor p27/Kip-1 expression in non-astrocytic and non-oligodendrocytic human nervous system tumors.

1 reference

7 January 2021

Basal cell carcinoma possibly originates from the outer root sheath and/or the bulge region of the vellus hair follicle

1 reference

7 January 2021

Sonic hedgehog signaling is essential for hair development

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7 January 2021

Induction of the hair growth phase in postnatal mice by localized transient expression of Sonic hedgehog

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7 January 2021

Mechanism-based target identification and drug discovery in cancer research

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7 January 2021

Creation of human tumour cells with defined genetic elements

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7 January 2021

Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells.

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7 January 2021

Size control in animal development

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7 January 2021

Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization

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7 January 2021

Tracing cell fates in human colorectal tumors from somatic microsatellite mutations: evidence of adenomas with stem cell architecture

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7 January 2021

Predominance of beta-catenin mutations and beta-catenin dysregulation in sporadic aggressive fibromatosis (desmoid tumor)

1 reference

7 January 2021

Activation of beta-catenin in epithelial and mesenchymal hepatoblastomas

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7 January 2021