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The Hedgehog and Wnt signalling pathways in cancer
scientific article (publication date: 17 May 2001)
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scholarly article
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Europe PubMed Central
title
The Hedgehog and Wnt signalling pathways in cancer
(English)
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author name string
J Taipale
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1
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P A Beachy
series ordinal
2
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language of work or name
English
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publication date
17 May 2001
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published in
Nature
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volume
411
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page(s)
349-54
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issue
6835
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cites work
Mechanisms of Wnt signaling in development
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Linking colorectal cancer to Wnt signaling
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Transducing Hedgehog: the story so far
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Hedgehog and patched in neural development and disease
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More surprises in the Hedgehog signaling pathway
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Secretion and localized transcription suggest a role in positional signaling for products of the segmentation gene hedgehog
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Transducing the hedgehog signal
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Cholesterol modification of hedgehog signaling proteins in animal development
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Identification of a palmitic acid-modified form of human Sonic hedgehog
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Functional binding of secreted molecules to heparan sulfate proteoglycans in Drosophila
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Dispatched, a novel sterol-sensing domain protein dedicated to the release of cholesterol-modified hedgehog from signaling cells
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Transmembrane molecular pump activity of Niemann-Pick C1 protein
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The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog
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Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened
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Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine
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Proteolysis that is inhibited by hedgehog targets Cubitus interruptus protein to the nucleus and converts it to a repressor
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Hedgehog elicits signal transduction by means of a large complex containing the kinesin-related protein costal2.
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Nuclear trafficking of Cubitus interruptus in the transcriptional regulation of Hedgehog target gene expression
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Feedback control of intercellular signalling in development
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WNT signalling molecules act in axis formation in the diploblastic metazoan Hydra.
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An LDL-receptor-related protein mediates Wnt signalling in mice
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A new member of the frizzled family from Drosophila functions as a Wingless receptor
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Functional interaction of beta-catenin with the transcription factor LEF-1
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Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome
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Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
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Identification of c-MYC as a target of the APC pathway
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Human homolog of patched, a candidate gene for the basal cell nevus syndrome
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Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome
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Activating Smoothened mutations in sporadic basal-cell carcinoma
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A frequent activated smoothened mutation in sporadic basal cell carcinomas
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A Notch affair.
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TGFbeta signaling in growth control, cancer, and heritable disorders
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Extracellular matrix-associated transforming growth factor-beta: role in cancer cell growth and invasion.
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The Hallmarks of Cancer
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Frequent clones of p53-mutated keratinocytes in normal human skin
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Hedgehog acts as a somatic stem cell factor in the Drosophila ovary
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Stem cells: a new lease on life
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Lessons from hereditary colorectal cancer
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Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4
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Sonic hedgehog promotes G(1) cyclin expression and sustained cell cycle progression in mammalian neuronal precursors
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Sonic hedgehog signaling is essential for hair development
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Induction of the hair growth phase in postnatal mice by localized transient expression of Sonic hedgehog
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Identifiers
DOI
10.1038/35077219
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Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
752411
Dimensions Publication ID
1021204853
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OpenCitations bibliographic resource ID
752411
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
752411
PubMed ID
11357142
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
752411
Springer Nature article ID
10.1038/35077219
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