(Q40727168)

English

"Aggrecanase" activity is implicated in tumour necrosis factor alpha mediated cartilage aggrecan breakdown but is not detected by an in vitro assay

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

23 September 2017

"Aggrecanase" activity is implicated in tumour necrosis factor alpha mediated cartilage aggrecan breakdown but is not detected by an in vitro assay (English)

1 reference

Europe PubMed Central

PMC publication ID

23 September 2017

0 references

1 reference

based on heuristic

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author name string

Buttle DJ

1

1 reference

Europe PubMed Central

PMC publication ID

23 September 2017

Fowles A

2

1 reference

Europe PubMed Central

PMC publication ID

23 September 2017

Ilic MZ

3

1 reference

Europe PubMed Central

PMC publication ID

23 September 2017

Handley CJ

4

1 reference

Europe PubMed Central

PMC publication ID

23 September 2017

language of work or name

0 references

publication date

1 June 1997

1 reference

Europe PubMed Central

PMC publication ID

23 September 2017

Journal of Clinical Pathology

1 reference

Europe PubMed Central

PMC publication ID

23 September 2017

50

1 reference

Europe PubMed Central

PMC publication ID

23 September 2017

3

1 reference

Europe PubMed Central

PMC publication ID

23 September 2017

153-159

1 reference

Europe PubMed Central

PMC publication ID

23 September 2017

THE LOSS OF PHENOTYPIC TRAITS BY DIFFERENTIATED CELLS IN VITRO, I. DEDIFFERENTIATION OF CARTILAGE CELLS

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=379611

25 September 2017

Cloning of a novel membrane-linked metalloproteinase from human myeloma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=379611

25 September 2017

Evolutionary families of metallopeptidases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=379611

25 September 2017

Increased expression of CD44 in bovine articular chondrocytes by catabolic cellular mediators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=379611

25 September 2017

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=379611

25 September 2017

The structure of aggrecan fragments in human synovial fluid. Evidence for the involvement in osteoarthritis of a novel proteinase which cleaves the Glu 373-Ala 374 bond of the interglobular domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=379611

25 September 2017

Inhibition of interleukin 1 beta induced rat and human cartilage degradation in vitro by the metalloproteinase inhibitor U27391.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=379611

25 September 2017

Cell-mediated catabolism of aggrecan. Evidence that cleavage at the "aggrecanase" site (Glu373-Ala374) is a primary event in proteolysis of the interglobular domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=379611

25 September 2017

A cartilage explant system for studies on aggrecan structure, biosynthesis and catabolism in discrete zones of the mammalian growth plate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=379611

15 June 2018

Monoclonal antibodies that specifically recognize neoepitope sequences generated by 'aggrecanase' and matrix metalloproteinase cleavage of aggrecan: application to catabolism in situ and in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=379611

15 June 2018

Pig catabolin is a form of interleukin 1. Cartilage and bone resorb, fibroblasts make prostaglandin and collagenase, and thymocyte proliferation is augmented in response to one protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=379611

15 June 2018

Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=379611

15 June 2018

Inhibition of interleukin 1-stimulated cartilage proteoglycan degradation by a lipophilic inactivator of cysteine endopeptidases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=379611

15 June 2018

N-terminal sequence of proteoglycan fragments isolated from medium of interleukin-1-treated articular-cartilage cultures. Putative site(s) of enzymic cleavage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=379611

15 June 2018

Mechanism of catabolism of aggrecan by articular cartilage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=379611

15 June 2018

The hyaluronan receptor (CD44) participates in the uptake and degradation of hyaluronan

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=379611

15 June 2018

Assay of proteoglycan degradation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=379611

19 August 2018

Potent collagenase inhibitors prevent interleukin-1-induced cartilage degradation in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=379611

4 November 2018

A synthetic peptide metalloproteinase inhibitor, but not TIMP, prevents the breakdown of proteoglycan within articular cartilage in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/9292151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Degradation of type II collagen, but not proteoglycan, correlates with matrix metalloproteinase activity in cartilage explant cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/9292151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Catabolism of aggrecan in cartilage explants. Identification of a major cleavage site within the interglobular domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/9292151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mapping by monoclonal antibody detection of glycosaminoglycans in connective tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/9292151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumour necrosis factor α stimulates resorption and inhibits synthesis of proteoglycan in cartilage

1 reference

https://pubmed.ncbi.nlm.nih.gov/9292151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human cartilage is degraded by rheumatoid arthritis synovial fluid but not by recombinant cytokines in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/9292151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of human articular chondrocyte CD44 isoform expression and function in health and disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9292151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The structure of aggrecan fragments in human synovial fluid. Evidence that aggrecanase mediates cartilage degradation in inflammatory joint disease, joint injury, and osteoarthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9292151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of synovial tissue on the breakdown of articular cartilage in organ culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/9292151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane-associated metalloproteinase recognized by characteristic cleavage of myelin basic protein: assay and isolation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9292151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of proteolytic enzymes on the mechanical properties of adult human articular cartilage

1 reference

https://pubmed.ncbi.nlm.nih.gov/9292151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of exogenous hyaluronan and hyaluronan oligosaccharides on hyaluronan and aggrecan synthesis and catabolism in adult articular cartilage explants

1 reference

https://pubmed.ncbi.nlm.nih.gov/9292151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The extracellular processing and catabolism of hyaluronan in cultured adult articular cartilage explants

1 reference

https://pubmed.ncbi.nlm.nih.gov/9292151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of interleukin 1-mediated proteoglycan degradation in bovine articular cartilage explants by addition of sodium hyaluronate

1 reference

https://pubmed.ncbi.nlm.nih.gov/9292151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin 1 preferentially stimulates the production of tissue-type plasminogen activator by human articular chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9292151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of cartilage proteoglycan release by a specific inactivator of cathepsin B and an inhibitor of matrix metalloproteinases. Evidence for two converging pathways of chondrocyte-mediated proteoglycan degradation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9292151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1136/MP.50.3.153

1 reference

Europe PubMed Central

PMC publication ID

23 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

23 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

23 September 2017

ResearchGate publication ID

0 references

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