(Q40741169)

23 September 2017

A bivalent Huntingtin binding peptide suppresses polyglutamine aggregation and pathogenesis in Drosophila (English)

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23 September 2017

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Aleksey Kazantsev

1

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23 September 2017

Heli A Walker

2

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23 September 2017

Natalia Slepko

3

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23 September 2017

James E Bear

4

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23 September 2017

Elizabeth Preisinger

5

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23 September 2017

Joan S Steffan

6

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23 September 2017

Ya-Zhen Zhu

7

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23 September 2017

Frank B Gertler

8

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23 September 2017

David E Housman

9

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23 September 2017

J Lawrence Marsh

10

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23 September 2017

Leslie M Thompson

11

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23 September 2017

language of work or name

English

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publication date

25 March 2002

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23 September 2017

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23 September 2017

30

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23 September 2017

367-376

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23 September 2017

4

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https://scigraph.springernature.com/pub.10.1038/ng864

23 September 2017

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cites work

Glutamine repeats and neurodegeneration

1 reference

7 January 2021

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

1 reference

7 January 2021

1 reference

7 January 2021

CAG repeat number governs the development rate of pathology in Huntington's disease

1 reference

7 January 2021

Protein aggregation and pathogenesis of Huntington's disease: mechanisms and correlations

1 reference

7 January 2021

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

1 reference

7 January 2021

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

1 reference

7 January 2021

Ultrastructural localization and progressive formation of neuropil aggregates in Huntington's disease transgenic mice

1 reference

7 January 2021

Protein fate in neurodegenerative proteinopathies: polyglutamine diseases join the (mis)fold

1 reference

7 January 2021

Insoluble detergent-resistant aggregates form between pathological and nonpathological lengths of polyglutamine in mammalian cells

1 reference

7 January 2021

Evidence for proteasome involvement in polyglutamine disease: localization to nuclear inclusions in SCA3/MJD and suppression of polyglutamine aggregation in vitro

1 reference

7 January 2021

Aberrant interactions of transcriptional repressor proteins with the Huntington's disease gene product, huntingtin

1 reference

7 January 2021

Analysis of the role of heat shock protein (Hsp) molecular chaperones in polyglutamine disease

1 reference

7 January 2021

Amyloid formation by mutant huntingtin: threshold, progressivity and recruitment of normal polyglutamine proteins

1 reference

7 January 2021

The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription

1 reference

7 January 2021

Identities of sequestered proteins in aggregates from cells with induced polyglutamine expression

1 reference

7 January 2021

Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity

1 reference

7 January 2021

Accumulation of mutant huntingtin fragments in aggresome-like inclusion bodies as a result of insufficient protein degradation

1 reference

7 January 2021

Recruitment and the role of nuclear localization in polyglutamine-mediated aggregation

1 reference

7 January 2021

CREB-binding protein sequestration by expanded polyglutamine

1 reference

7 January 2021

Glutamine repeats as polar zippers: their possible role in inherited neurodegenerative diseases

1 reference

7 January 2021

Crystal structure of TFIID TATA-box binding protein

1 reference

7 January 2021

Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: implications for Huntington's disease pathology

1 reference

7 January 2021

Polyglutamine aggregation behavior in vitro supports a recruitment mechanism of cytotoxicity

1 reference

7 January 2021

Hsp70 and hsp40 chaperones can inhibit self-assembly of polyglutamine proteins into amyloid-like fibrils

1 reference

7 January 2021

Expanded polyglutamine peptides alone are intrinsically cytotoxic and cause neurodegeneration in Drosophila

1 reference

7 January 2021

Genetic suppression of polyglutamine toxicity in Drosophila

1 reference

7 January 2021

Mechanisms of chaperone suppression of polyglutamine disease: selectivity, synergy and modulation of protein solubility in Drosophila.

1 reference

7 January 2021

Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70.

1 reference

7 January 2021

Identification of genes that modify ataxin-1-induced neurodegeneration.

1 reference

7 January 2021

Context generalization in Drosophila visual learning requires the mushroom bodies.

1 reference

7 January 2021

Mushroom body ablation impairs short-term memory and long-term memory of courtship conditioning in Drosophila melanogaster.

1 reference

7 January 2021

The emergence of order in the Drosophila pupal retina.

1 reference

7 January 2021

Neuronal differentiation in Drosophila ommatidium.

1 reference

7 January 2021

Beta-sheet breaker peptides inhibit fibrillogenesis in a rat brain model of amyloidosis: implications for Alzheimer's therapy.

1 reference

7 January 2021

In vivo reversal of amyloid-beta lesions in rat brain.

1 reference

7 January 2021

Inhibition of polyglutamine protein aggregation and cell death by novel peptides identified by phage display screening

1 reference

7 January 2021

"Fatal attractions" of proteins. A comprehensive hypothetical mechanism underlying Alzheimer's disease and other neurodegenerative disorders.

1 reference

7 January 2021

Amyloid-like inclusions in Huntington's disease.

1 reference

7 January 2021

Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1

1 reference

7 January 2021

Transgenic mice in the study of polyglutamine repeat expansion diseases.

1 reference

7 January 2021

Huntingtin aggregate-associated axonal degeneration is an early pathological event in Huntington's disease mice.

1 reference

7 January 2021

Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease

1 reference

7 January 2021

Bacterial and yeast chaperones reduce both aggregate formation and cell death in mammalian cell models of Huntington's disease

1 reference

7 January 2021

Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

1 reference

7 January 2021

Ataxin-1 nuclear localization and aggregation: role in polyglutamine-induced disease in SCA1 transgenic mice.

1 reference

7 January 2021

Amino acids in a region of ataxin-1 outside of the polyglutamine tract influence the course of disease in SCA1 transgenic mice.

1 reference

7 January 2021

Two-step process for photoreceptor formation in Drosophila.

1 reference

7 January 2021

Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila

1 reference

7 January 2021

In vivo protein transduction: delivery of a biologically active protein into the mouse

1 reference

7 January 2021

Recombinant proteins for neurodegenerative diseases: the delivery issue

1 reference

7 January 2021

Epidermal immunization by a needle-free powder delivery technology: Immunogenicity of influenza vaccine and protection in mice

1 reference

7 January 2021

Neuroprotective effects of creatine in a transgenic mouse model of Huntington's disease.

1 reference

7 January 2021

Negative regulation of fibroblast motility by Ena/VASP proteins

1 reference

7 January 2021

Genetic Transformation of Drosophila with Transposable Element Vectors

1 reference

7 January 2021

Transposition of cloned P elements into Drosophila germ line chromosomes.

1 reference

7 January 2021

Distinct morphogenetic functions of similar small GTPases: Drosophila Drac1 is involved in axonal outgrowth and myoblast fusion

1 reference

7 January 2021

Identifiers

DOI

10.1038/NG864

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Dimensions Publication ID

23 September 2017

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