(Q40745345)

English

Mutations in the UL97 ORF of ganciclovir-resistant clinical cytomegalovirus isolates differentially affect GCV phosphorylation as determined in a recombinant vaccinia virus system

scientific article published on April 2002

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

Mutations in the UL97 ORF of ganciclovir-resistant clinical cytomegalovirus isolates differentially affect GCV phosphorylation as determined in a recombinant vaccinia virus system (English)

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

phosphorylation

1 reference

based on heuristic

inferred from title

object named as

vaccinia virus

1 reference

based on heuristic

inferred from title

Fausto Baldanti

1

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

10

object named as

Thomas Mertens

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

author name string

Detlef Michel

2

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

Lavinia Simoncini

3

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

Maria Heuschmid

4

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

Albert Zimmermann

5

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

Rosalba Minisini

6

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

Peter Schaarschmidt

7

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

Thomas Schmid

8

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

Giuseppe Gerna

9

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

publication date

1 April 2002

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

number of pages

9

1 reference

based on heuristic

inferred from page(s)

Antiviral Research

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Europe PubMed Central

PubMed publication ID

23 September 2017

54

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Europe PubMed Central

PubMed publication ID

23 September 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

59-67

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

Failure of ganciclovir treatment associated with selection of a ganciclovir-resistant cytomegalovirus strain in a lung transplant recipient.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2801%2900211-X

7 January 2021

based on heuristic

inferred from DOI database lookup

A three-nucleotide deletion in the UL97 open reading frame is responsible for the ganciclovir resistance of a human cytomegalovirus clinical isolate

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2801%2900211-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Ganciclovir resistance as a result of oral ganciclovir in a heart transplant recipient with multiple human cytomegalovirus strains in blood

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2801%2900211-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Single amino acid changes in the DNA polymerase confer foscarnet resistance and slow-growth phenotype, while mutations in the UL97-encoded phosphotransferase confer ganciclovir resistance in three double-resistant human cytomegalovirus strains recov

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2801%2900211-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Detection of ganciclovir resistance mutations quantitation of cytomegalovirus (CMV) DNA in leukocytes of patients with fatal disseminated CMV disease

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2801%2900211-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Alpha-, beta- and gammaherpesviruses encode a putative phosphotransferase

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2801%2900211-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Analysis of the UL97 phosphotransferase coding sequence in clinical cytomegalovirus isolates and identification of mutations conferring ganciclovir resistance.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2801%2900211-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Frequency of UL97 phosphotransferase mutations related to ganciclovir resistance in clinical cytomegalovirus isolates

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2801%2900211-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Evolution of mutations conferring multidrug resistance during prophylaxis and therapy for cytomegalovirus disease

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2801%2900211-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Prevalence of Resistance in Patients Receiving Ganciclovir for Serious Cytomegalovirus Infection

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2801%2900211-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Prediction of cytomegalovirus load and resistance patterns after antiviral chemotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2801%2900211-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Progressive disease due to ganciclovir-resistant cytomegalovirus in immunocompromised patients

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2801%2900211-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Monitoring of ganciclovir sensitivity of multiple human cytomegalovirus strains coinfecting blood of an AIDS patient by an immediate-early antigen plaque assay.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2801%2900211-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Novel mutation in the UL97 gene of a clinical cytomegalovirus strain conferring resistance to ganciclovir

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2801%2900211-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutations conferring ganciclovir resistance in a cohort of patients with acquired immunodeficiency syndrome and cytomegalovirus retinitis.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2801%2900211-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Foscarnet therapy for ganciclovir-resistant cytomegalovirus retinitis in patients with AIDS.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2801%2900211-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Cytomegalovirus isolate resistant to ganciclovir and foscarnet from a marrow transplant patient

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2801%2900211-X

7 January 2021

based on heuristic

inferred from DOI database lookup

A general method for rapid site-directed mutagenesis using the polymerase chain reaction.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2801%2900211-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Emergence of ganciclovir-resistant cytomegalovirus disease among recipients of solid-organ transplants.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2801%2900211-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Human cytomegalovirus UL97 open reading frame encodes a protein that phosphorylates the antiviral nucleoside analogue ganciclovir

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2801%2900211-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutation in the UL97 open reading frame of human cytomegalovirus strains resistant to ganciclovir.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2801%2900211-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular analysis of human cytomegalovirus strains from two lung transplant recipients with the same donor

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2801%2900211-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Functional regions of the human cytomegalovirus protein pUL97 involved in nuclear localization and phosphorylation of ganciclovir and pUL97 itself

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2801%2900211-X

7 January 2021

based on heuristic

inferred from DOI database lookup

A recombinant human cytomegalovirus with a large deletion in UL97 has a severe replication deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2801%2900211-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Development of ganciclovir resistance during treatment of primary cytomegalovirus infection after liver transplantation

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2801%2900211-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Ganciclovir-resistant cytomegalovirus clinical isolates: mode of resistance to ganciclovir

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2801%2900211-X

7 January 2021

based on heuristic

inferred from DOI database lookup

A protein kinase homologue controls phosphorylation of ganciclovir in human cytomegalovirus-infected cells

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2801%2900211-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Comparison between human cytomegalovirus pUL97 and murine cytomegalovirus (MCMV) pM97 expressed by MCMV and vaccinia virus: pM97 does not confer ganciclovir sensitivity

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2801%2900211-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutations in human cytomegalovirus UL97 gene confer clinical resistance to ganciclovir and can be detected directly in patient plasma

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2801%2900211-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Early emergence of ganciclovir-resistant human cytomegalovirus strains in children with primary combined immunodeficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2801%2900211-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphorylation of aciclovir, ganciclovir, penciclovir and S2242 by the cytomegalovirus UL97 protein: a quantitative analysis using recombinant vaccinia viruses

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2801%2900211-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0166-3542(01)00211-X

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

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