(Q40751291)

23 September 2017

title

5-Fluoroindole-3-acetic acid: a prodrug activated by a peroxidase with potential for use in targeted cancer therapy (English)

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23 September 2017

2

Olga Greco

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23 September 2017

3

Gabi U Dachs

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23 September 2017

Lisa K Folkes

1

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23 September 2017

Michael R L Stratford

series ordinal

4

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23 September 2017

Peter Wardman

series ordinal

5

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23 September 2017

language of work or name

English

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publication date

1 January 2002

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23 September 2017

published in

Biochemical Pharmacology

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23 September 2017

volume

63

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23 September 2017

issue

2

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23 September 2017

page(s)

265-272

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The First Bagshawe lecture. Towards generating cytotoxic agents at cancer sites

23 September 2017

cites work

1 reference

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Toward targeted "oxidation therapy" of cancer: peroxidase-catalysed cytotoxicity of indole-3-acetic acids

7 January 2021

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Amplification of oxidative stress by decarboxylation: a new strategy in anti-tumour drug design

7 January 2021

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Enhancement of Lipid Peroxidation by Indole-3-Acetic Acid and Derivatives: Substituent Effects

7 January 2021

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Enhancement of peroxidase-induced lipid peroxidation by indole-3-acetic acid: effect of antioxidants

7 January 2021

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Peroxidase-catalyzed effects of indole-3-acetic acid and analogues on lipid membranes, DNA, and mammalian cells in vitro

7 January 2021

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Oxidative activation of indole-3-acetic acids to cytotoxic species- a potential new role for plant auxins in cancer therapy

7 January 2021

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Oxidation of indole-3-acetic acid by peroxidase: involvement of reduced peroxidase and compound III with superoxide as a product

7 January 2021

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The reaction of oxygen with radicals from oxidation of tryptophan and indole-3-acetic acid

7 January 2021

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Identification of skatolyl hydroperoxide and its role in the peroxidase-catalysed oxidation of indol-3-yl acetic acid

7 January 2021

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The conversion of indole-3-acetic acid to 3-methyleneoxindole in the presence of peroxidase

7 January 2021

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The binding of the peroxidase oxidation products of indole-3-acetic acid to histone

7 January 2021

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Interpretation of the reactivity of peroxidase compounds I and II with phenols by the Marcus equation.

7 January 2021

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Rates of reaction of indoleacetic acids with horseradish peroxidase compound I and their dependence on the redox potentials.

7 January 2021

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Factors controlling the substrate specificity of peroxidases: kinetics and thermodynamics of the reaction of horseradish peroxidase compound I with phenols and indole-3-acetic acids

7 January 2021

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Analysis of biological thiols: quantitative determination of thiols at the picomole level based upon derivatization with monobromobimanes and separation by cation-exchange chromatography

7 January 2021

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Melatonin attenuates hydrogen peroxide toxicity in MCF7 cells only at pharmacological concentrations.

7 January 2021

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Effect of glutathione depletion on inhibition of cell cycle progression and induction of apoptosis by melphalan (L-phenylalanine mustard) in human colorectal cancer cells

7 January 2021

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Peroxidase-H2O2 catalyzed incorporation of auxin derivatives into sRNA.

7 January 2021

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Doxorubicin sensitizes human bladder carcinoma cells to Fas-mediated cytotoxicity

7 January 2021

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7 January 2021

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Cellular glutathione as a determinant of the sensitivity of colorectal tumour cell-lines to ZD2767 antibody-directed enzyme prodrug therapy (ADEPT)

7 January 2021

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Hypoglycemic action of indole-3-acetic acid by mouth in patients with diabetes mellitus.

7 January 2021

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Development of a novel enzyme/prodrug combination for gene therapy of cancer: horseradish peroxidase/indole-3-acetic acid

7 January 2021

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10.1016/S0006-2952(01)00868-1

7 January 2021

Identifiers

DOI

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23 September 2017

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