(Q40757461)

English

Consequences of mevalonate depletion. Differential transcriptional, translational, and post-translational up-regulation of Ras, Rap1a, RhoA, AND RhoB.

scientific article published on 11 January 2002

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scholarly article

1 reference

Europe PubMed Central

23 September 2017

Consequences of mevalonate depletion. Differential transcriptional, translational, and post-translational up-regulation of Ras, Rap1a, RhoA, AND RhoB. (English)

1 reference

Europe PubMed Central

23 September 2017

author name string

Sarah A Holstein

1

1 reference

Europe PubMed Central

23 September 2017

Christine L Wohlford-Lenane

2

1 reference

Europe PubMed Central

23 September 2017

Raymond J Hohl

3

1 reference

Europe PubMed Central

23 September 2017

language of work or name

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publication date

11 January 2002

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Europe PubMed Central

23 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

23 September 2017

277

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Europe PubMed Central

23 September 2017

12

1 reference

Europe PubMed Central

23 September 2017

10678-10682

1 reference

Europe PubMed Central

23 September 2017

Increasing complexity of the Ras signaling pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111369200

21 January 2018

Coassociation of Rap1A and Ha-Ras with Raf-1 N-terminal region interferes with ras-dependent activation of Raf-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111369200

21 January 2018

Rho as a regulator of the cytoskeleton.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111369200

21 January 2018

Rho GTPases and signaling networks

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111369200

21 January 2018

RhoB is dispensable for mouse development, but it modifies susceptibility to tumor formation as well as cell adhesion and growth factor signaling in transformed cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111369200

21 January 2018

All ras proteins are polyisoprenylated but only some are palmitoylated

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111369200

21 January 2018

Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111369200

21 January 2018

p21ras is modified by a farnesyl isoprenoid

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111369200

21 January 2018

The COOH-terminal domain of the Rap1A (Krev-1) protein is isoprenylated and supports transformation by an H-Ras:Rap1A chimeric protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111369200

21 January 2018

Prenylation of RhoB is required for its cell transforming function but not its ability to activate serum response element-dependent transcription

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111369200

21 January 2018

RhoA prenylation is required for promotion of cell growth and transformation and cytoskeleton organization but not for induction of serum response element transcription.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111369200

21 January 2018

Regulation of the mevalonate pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111369200

21 January 2018

Genetic and pharmacological suppression of oncogenic mutations in ras genes of yeast and humans.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111369200

21 January 2018

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111369200

21 January 2018

Metabolic turnover of human c-rasH p21 protein of EJ bladder carcinoma and its normal cellular and viral homologs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111369200

21 January 2018

Post-translational processing of RhoA. Carboxyl methylation of the carboxyl-terminal prenylcysteine increases the half-life of Rhoa

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111369200

21 January 2018

Non-lipid-related effects of statins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111369200

21 January 2018

Locking a leukocyte integrin with statins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111369200

21 January 2018

Structural basis for LFA-1 inhibition upon lovastatin binding to the CD11a I-domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111369200

21 January 2018

Statins selectively inhibit leukocyte function antigen-1 by binding to a novel regulatory integrin site

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111369200

21 January 2018

Transcriptional activation of the small GTPase gene rhoB by genotoxic stress is regulated via a CCAAT element

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111369200

21 January 2018

rhoB encoding a UV-inducible Ras-related small GTP-binding protein is regulated by GTPases of the Rho family and independent of JNK, ERK, and p38 MAP kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111369200

21 January 2018

Regulation of gene expression by SREBP and SCAP.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111369200

21 January 2018

HMG-CoA reductase inhibitors for treatment of hypercholesterolemia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111369200

21 January 2018

Farnesyltransferase inhibitors alter the prenylation and growth-stimulating function of RhoB

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111369200

21 January 2018

Post-transcriptional regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase by mevalonate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111369200

21 January 2018

Differential effects of monoterpenes and lovastatin on RAS processing

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111369200

21 January 2018

Identifiers

10.1074/JBC.M111369200

1 reference

Europe PubMed Central

23 September 2017

1 reference

Europe PubMed Central

23 September 2017

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