(Q40760628)

23 September 2017

title

The cellular uptake and metabolism of clodronate in RAW 264 macrophages (English)

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23 September 2017

Mönkkönen H

1

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23 September 2017

Rogers MJ

2

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23 September 2017

Makkonen N

3

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23 September 2017

Niva S

4

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23 September 2017

Auriola S

5

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23 September 2017

Mönkkönen J

6

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23 September 2017

language of work or name

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1 November 2001

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23 September 2017

published in

Pharmaceutical Research

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23 September 2017

volume

18

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23 September 2017

issue

11

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23 September 2017

page(s)

1550-1555

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Growth inhibition of macrophage-like and other cell types by liposome-encapsulated, calcium-bound, and free bisphosphonates in vitro

23 September 2017

cites work

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12 December 2020

Bisphosphonates are incorporated into adenine nucleotides by human aminoacyl-tRNA synthetase enzymes

1 reference

12 December 2020

Liposomal clodronate eliminates synovial macrophages, reduces inflammation and ameliorates joint destruction in antigen-induced arthritis

1 reference

12 December 2020

Long-term amelioration of rat adjuvant arthritis following systemic elimination of macrophages by clodronate-containing liposomes

1 reference

12 December 2020

The molecular mechanism of action of the antiresorptive and antiinflammatory drug clodronate: evidence for the formation in vivo of a metabolite that inhibits bone resorption and causes osteoclast and macrophage apoptosis

1 reference

12 December 2020

Bisphosphonates: a review of their pharmacokinetic properties

1 reference

12 December 2020

Cytotoxicity of dichloromethane diphosphonate and of 1-hydroxyethane-1,1-diphosphonate in the amoebae of the slime mould Dictyostelium discoideum. A 31P NMR study

1 reference

12 December 2020

Macrophage-like RAW 264 cell line and time-resolved fluoroimmunoassay (TRFIA) as tools in screening drug effects on cytokine secretion

1 reference

12 December 2020

Clodronate and liposome-encapsulated clodronate are metabolized to a toxic ATP analog, adenosine 5'-(beta, gamma-dichloromethylene) triphosphate, by mammalian cells in vitro.

1 reference

12 December 2020

Effect of liposomal and free bisphosphonates on the IL-1 beta, IL-6 and TNF alpha secretion from RAW 264 cells in vitro

1 reference

12 December 2020

Synovial macrophage depletion with clodronate-containing liposomes in rheumatoid arthritis

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12 December 2020

The subcellular distribution of [14C]dichloromethylenebisphosphonate and [14C]1-hydroxyethylidene-1,1-bisphosphonate in cultured calvaria cells

1 reference

12 December 2020

Effects of low-dose, noncytotoxic, intraarticular liposomal clodronate on development of erosions and proteoglycan loss in established antigen-induced arthritis in rabbits

1 reference

12 December 2020

Different effects of three bisphosphonates on nitric oxide production by RAW 264 macrophage-like cells in vitro

1 reference

12 December 2020

Inhibition of growth of Dictyostelium discoideum amoebae by bisphosphonate drugs is dependent on cellular uptake

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12 December 2020

Bisphosphonates promote apoptosis in murine osteoclasts in vitro and in vivo

1 reference

12 December 2020

Incorporation of bisphosphonates into adenine nucleotides by amoebae of the cellular slime mould Dictyostelium discoideum.

1 reference

12 December 2020

Contrasting effects of alendronate and clodronate on RAW 264 macrophages: the role of a bisphosphonate metabolite

1 reference

12 December 2020

Analysis of an adenine nucleotide-containing metabolite of clodronate using ion pair high-performance liquid chromatography-electrospray ionisation mass spectrometry

1 reference

12 December 2020

Characteristics of clodronate-induced apoptosis in osteoclasts and macrophages.

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12 December 2020

Purine and pyrimidine compounds in murine peritoneal macrophages cultured in vitro

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12 December 2020

Effects of lidocaine on cytosolic pH regulation and stimulus-induced effector functions in alveolar macrophages.

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12 December 2020

The effects of liposome-encapsulated and free clodronate on the growth of macrophage-like cells in vitro: the role of calcium and iron

1 reference

12 December 2020

Metabolism of halogenated bisphosphonates by the cellular slime mould dictyostelium discoideum

1 reference

12 December 2020

Cellular and molecular mechanisms of action of bisphosphonates

1 reference

12 December 2020

Identification of adenine nucleotide-containing metabolites of bisphosphonate drugs using ion-pair liquid chromatography-electrospray mass spectrometry.

1 reference

12 December 2020

Bisphosphonate action. Alendronate localization in rat bone and effects on osteoclast ultrastructure

1 reference

12 December 2020

Identifiers

DOI

10.1023/A:1013026313647

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23 September 2017

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