(Q40762284)

English

A radicicol derivative, KF58333, inhibits expression of hypoxia-inducible factor-1alpha and vascular endothelial growth factor, angiogenesis and growth of human breast cancer xenografts

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

29 June 2018

http://europepmc.org/abstract/PMC/5926684

A radicicol derivative, KF58333, inhibits expression of hypoxia-inducible factor-1alpha and vascular endothelial growth factor, angiogenesis and growth of human breast cancer xenografts (English)

1 reference

Europe PubMed Central

PMC publication ID

29 June 2018

http://europepmc.org/abstract/PMC/5926684

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1 reference

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author name string

J Kurebayashi

1

1 reference

Europe PubMed Central

PMC publication ID

29 June 2018

http://europepmc.org/abstract/PMC/5926684

T Otsuki

2

1 reference

Europe PubMed Central

PMC publication ID

29 June 2018

http://europepmc.org/abstract/PMC/5926684

M Kurosumi

3

1 reference

Europe PubMed Central

PMC publication ID

29 June 2018

http://europepmc.org/abstract/PMC/5926684

S Soga

4

1 reference

Europe PubMed Central

PMC publication ID

29 June 2018

http://europepmc.org/abstract/PMC/5926684

S Akinaga

5

1 reference

Europe PubMed Central

PMC publication ID

29 June 2018

http://europepmc.org/abstract/PMC/5926684

H Sonoo

6

1 reference

Europe PubMed Central

PMC publication ID

29 June 2018

http://europepmc.org/abstract/PMC/5926684

publication date

1 December 2001

1 reference

Europe PubMed Central

PMC publication ID

29 June 2018

http://europepmc.org/abstract/PMC/5926684

number of pages

10

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based on heuristic

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Japanese Journal of Cancer Research

1 reference

Europe PubMed Central

PMC publication ID

29 June 2018

http://europepmc.org/abstract/PMC/5926684

92

1 reference

Europe PubMed Central

PMC publication ID

29 June 2018

http://europepmc.org/abstract/PMC/5926684

12

1 reference

Europe PubMed Central

PMC publication ID

29 June 2018

http://europepmc.org/abstract/PMC/5926684

1342-1351

1 reference

Europe PubMed Central

PMC publication ID

29 June 2018

http://europepmc.org/abstract/PMC/5926684

Stereospecific antitumor activity of radicicol oxime derivatives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926684

30 June 2018

Inhibition of signal transduction by the Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin results in cytostasis and apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926684

30 June 2018

Paradoxical hormone responses of KPL-1 breast cancer cells in vivo: a significant role of angiogenesis in tumor growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926684

30 June 2018

Hypoxia, clonal selection, and the role of HIF-1 in tumor progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926684

30 June 2018

Vascular endothelial growth factor (VEGF)-driven actin-based motility is mediated by VEGFR2 and requires concerted activation of stress-activated protein kinase 2 (SAPK2/p38) and geldanamycin-sensitive phosphorylation of focal adhesion kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926684

30 June 2018

Estrogen receptors in human myeloma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926684

30 June 2018

Mechanism-based target identification and drug discovery in cancer research

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926684

30 June 2018

Tumor angiogenesis: past, present and the near future

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926684

30 June 2018

Structure and in vivo function of Hsp90.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926684

30 June 2018

Role of HIF-1 as a transcription factor involved in embryonic development, cancer progression and apoptosis (review).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926684

30 June 2018

Angiogenesis: how a tumor adapts to hypoxia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926684

30 June 2018

Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926684

30 June 2018

DT-Diaphorase expression and tumor cell sensitivity to 17-allylamino, 17-demethoxygeldanamycin, an inhibitor of heat shock protein 90

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926684

30 June 2018

Hypoxia-induced activation of HIF-1: role of HIF-1alpha-Hsp90 interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926684

30 June 2018

Overview of the trastuzumab (Herceptin) anti-HER2 monoclonal antibody clinical program in HER2-overexpressing metastatic breast cancer. Herceptin Multinational Investigator Study Group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926684

30 June 2018

Interaction of radicicol with members of the heat shock protein 90 family of molecular chaperones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926684

30 June 2018

Characterization of an oxygen/redox-dependent degradation domain of hypoxia-inducible factor alpha (HIF-alpha) proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926684

30 June 2018

KF25706, a novel oxime derivative of radicicol, exhibits in vivo antitumor activity via selective depletion of Hsp90 binding signaling molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926684

30 June 2018

Isolation and characterization of a new human breast cancer cell line, KPL-4, expressing the Erb B family receptors and interleukin-6.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926684

30 June 2018

A pure antiestrogen, ICI 182,780, stimulates the growth of tamoxifen-resistant KPL-1 human breast cancer cells in vivo but not in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926684

30 June 2018

The Hsp90 complex--a super-chaperone machine as a novel drug target

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926684

30 June 2018

Invasion-inhibiting factor 2-albumin conjugate inhibits invasion and spontaneous metastasis of MKL-4 human breast cancer cells transplanted into female nude mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926684

30 June 2018

Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: essential role for stress proteins in oncogenic transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926684

30 June 2018

A new human breast cancer cell line, KPL-1 secretes tumour-associated antigens and grows rapidly in female athymic nude mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926684

30 June 2018

Angiogenesis in cancer, vascular, rheumatoid and other disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926684

30 June 2018

Stereological methods based on point counting and unbiased counting frames for two-dimensional measurements in muscles: comparison with manual and image analysis methods

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926684

30 June 2018

Unusual expression and localization of heat-shock proteins in human tumor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926684

30 June 2018

Inhibition of heat shock protein 90 function by ansamycins causes the morphological and functional differentiation of breast cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926684

19 August 2018

p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926684

19 August 2018

Expression of vascular endothelial growth factor (VEGF) family members in breast cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926684

19 August 2018

Molecular cloning of cDNAs encoding hypoxia-inducible factor (HIF)-1alpha and -2alpha of bovine arterial endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926684

19 August 2018

Inhibition of Hsp90 function by ansamycins causes retinoblastoma gene product-dependent G1 arrest

1 reference

https://pubmed.ncbi.nlm.nih.gov/11749701

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential signaling by an anti-p185(HER2) antibody and heregulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/11749701

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Radicicol, a microbial cell differentiation modulator, inhibits in vivo angiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11749701

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novobiocin and related coumarins and depletion of heat shock protein 90-dependent signaling proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/11749701

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel oxime derivatives of radicicol induce erythroid differentiation associated with preferential G(1) phase accumulation against chronic myelogenous leukemia cells through destabilization of Bcr-Abl with Hsp90 complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/11749701

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of bcl-2 and apoptotic DNA fragmentation in human endometrial adenocarcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11749701

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1349-7006.2001.TB02159.X

1 reference

Europe PubMed Central

PMC publication ID

29 June 2018

http://europepmc.org/abstract/PMC/5926684

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

29 June 2018

http://europepmc.org/abstract/PMC/5926684

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

29 June 2018

http://europepmc.org/abstract/PMC/5926684

ResearchGate publication ID

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