(Q40765067)

23 September 2017

title

Glutathione dependence of caspase-8 activation at the death-inducing signaling complex (English)

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23 September 2017

2

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23 September 2017

Hannes Hentze

1

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23 September 2017

Markus Latta

3

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23 September 2017

Andreas Krueger

4

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23 September 2017

Peter H Krammer

5

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23 September 2017

Albrecht Wendel

6

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23 September 2017

language of work or name

English

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publication date

4 December 2001

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Journal of Biological Chemistry

23 September 2017

published in

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23 September 2017

volume

277

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23 September 2017

issue

7

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23 September 2017

page(s)

5588-5595

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FLICE is predominantly expressed as two functionally active isoforms, caspase-8/a and caspase-8/b.

23 September 2017

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21 January 2018

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Pro-caspase-3 is a major physiologic target of caspase-8.

21 January 2018

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Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

21 January 2018

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Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

21 January 2018

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Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death

21 January 2018

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

21 January 2018

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Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization

21 January 2018

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Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

21 January 2018

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Two CD95 (APO-1/Fas) signaling pathways

21 January 2018

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Review: The role of glutathione in the regulation of apoptosis

21 January 2018

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Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species

21 January 2018

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Signalling mechanisms and oxidative stress in apoptosis

21 January 2018

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Redox regulation of cellular signalling

21 January 2018

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Dual regulation of caspase activity by hydrogen peroxide: implications for apoptosis

21 January 2018

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Disulfiram inhibits TNF-alpha-induced cell death

21 January 2018

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Glutathione levels determine apoptosis in macrophages

21 January 2018

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Immunodominant B-cell domains of hepatitis C virus envelope proteins E1 and E2 identified during early and late time points of infection

21 January 2018

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Depletion of hepatic glutathione prevents death receptor-dependent apoptotic and necrotic liver injury in mice

21 January 2018

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Fas mediated apoptosis of human Jurkat T-cells: intracellular events and potentiation by redox-active alpha-lipoic acid

21 January 2018

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Regulation of interferon and retinoic acid-induced cell death activation through thioredoxin reductase

21 January 2018

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Thioredoxin participates in a cell death pathway induced by interferon and retinoid combination

21 January 2018

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Inhibition of caspase-3 by S-nitrosation and oxidation caused by nitric oxide

21 January 2018

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The role of c-FLIP in modulation of CD95-induced apoptosis

21 January 2018

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Monoclonal antibody-mediated tumor regression by induction of apoptosis.

21 January 2018

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Interleukin-1 beta converting enzyme.

21 January 2018

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Differential modulation of apoptosis sensitivity in CD95 type I and type II cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110766200

FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110766200

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110766200

Caspase structure, proteolytic substrates, and function during apoptotic cell death

21 January 2018

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Biochemical characteristics of caspases-3, -6, -7, and -8

21 January 2018

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Oxidative stress inhibits apoptosis in human lymphoma cells

21 January 2018

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A comparative study of apoptosis and necrosis in HepG2 cells: oxidant-induced caspase inactivation leads to necrosis

21 January 2018

1 reference

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Apoptosis or necrosis: intracellular levels of glutathione influence mode of cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110766200

Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110766200

Necrotic death pathway in Fas receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110766200

Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110766200

Emerging roles of caspase-3 in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110766200

Caspase activation involves the formation of the aposome, a large (approximately 700 kDa) caspase-activating complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110766200

Cellular glutathione status modulates polychlorinated biphenyl-induced stress response and apoptosis in vascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110766200

Mechanism of Dithiocarbamate Inhibition of Apoptosis: Thiol Oxidation by Dithiocarbamate Disulfides Directly Inhibits Processing of the Caspase-3 Proenzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110766200

Disulfiram is a potent inhibitor of proteases of the caspase family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110766200

Redox manipulation using the thiol-oxidizing agent diethyl maleate prevents hepatocellular necrosis and apoptosis in a rodent endotoxemia model

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110766200

Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110766200

Selenite negatively regulates caspase-3 through a redox mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110766200

Inhibition of mitochondrial ATP generation by nitric oxide switches apoptosis to necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110766200

Hydrogen peroxide inhibits activation, not activity, of cellular caspase-3 in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110766200

Redox control of caspase-3 activity by thioredoxin and other reduced proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110766200

21 January 2018

Identifiers

DOI

10.1074/JBC.M110766200

1 reference

23 September 2017

1 reference