(Q40769024)

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Phosphoinositide-specific inositol polyphosphate 5-phosphatase IV inhibits Akt/protein kinase B phosphorylation and leads to apoptotic cell death

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Europe PubMed Central

PubMed publication ID

23 September 2017

Phosphoinositide-specific inositol polyphosphate 5-phosphatase IV inhibits Akt/protein kinase B phosphorylation and leads to apoptotic cell death (English)

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

apoptotic process

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phosphorylation

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author name string

Marina V Kisseleva

1

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

Li Cao

2

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

Philip W Majerus

3

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

language of work or name

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publication date

12 November 2001

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Europe PubMed Central

PubMed publication ID

23 September 2017

number of pages

7

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Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

23 September 2017

277

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Europe PubMed Central

PubMed publication ID

23 September 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

6266-6272

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

The role of phosphoinositide 3-kinase lipid products in cell function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105969200

21 January 2018

Phosphatidylinositol 4-phosphate 5-kinase type I is regulated through phosphorylation response by extracellular stimuli

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105969200

21 January 2018

Phosphatidylinositol phosphate kinases, a multifaceted family of signaling enzymes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105969200

21 January 2018

The role of phosphatases in inositol signaling reactions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105969200

21 January 2018

Mechanisms and consequences of activation of protein kinase B/Akt

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105969200

21 January 2018

The PI3K-PDK1 connection: more than just a road to PKB

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105969200

21 January 2018

Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105969200

21 January 2018

The isolation and characterization of a cDNA encoding phospholipid-specific inositol polyphosphate 5-phosphatase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105969200

21 January 2018

Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105969200

21 January 2018

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105969200

21 January 2018

Dual Role of Phosphatidylinositol-3,4,5-trisphosphate in the Activation of Protein Kinase B

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105969200

21 January 2018

Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105969200

21 January 2018

AKT/PKB and other D3 phosphoinositide-regulated kinases: kinase activation by phosphoinositide-dependent phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105969200

21 January 2018

Akt activation by growth factors is a multiple-step process: the role of the PH domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105969200

21 January 2018

Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105969200

21 January 2018

A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105969200

21 January 2018

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105969200

21 January 2018

Mitogenic activation, phosphorylation, and nuclear translocation of protein kinase Bbeta

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105969200

21 January 2018

5' phospholipid phosphatase SHIP-2 causes protein kinase B inactivation and cell cycle arrest in glioblastoma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105969200

21 January 2018

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105969200

21 January 2018

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105969200

21 January 2018

Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105969200

21 January 2018

PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105969200

21 January 2018

SHIP is a negative regulator of growth factor receptor-mediated PKB/Akt activation and myeloid cell survival

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105969200

21 January 2018

Overexpression of SH2-containing inositol phosphatase 2 results in negative regulation of insulin-induced metabolic actions in 3T3-L1 adipocytes via its 5'-phosphatase catalytic activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105969200

21 January 2018

The inositol phosphatase SHIP inhibits Akt/PKB activation in B cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105969200

21 January 2018

FcgammaRIIb modulation of surface immunoglobulin-induced Akt activation in murine B cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105969200

21 January 2018

Phosphatidylinositol-4-phosphate 5-kinase isozymes catalyze the synthesis of 3-phosphate-containing phosphatidylinositol signaling molecules

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105969200

21 January 2018

Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105969200

21 January 2018

Epidermal growth factor protects epithelial cells against Fas-induced apoptosis. Requirement for Akt activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105969200

21 January 2018

Regulation of apoptosis by phosphatidylinositol 4,5-bisphosphate inhibition of caspases, and caspase inactivation of phosphatidylinositol phosphate 5-kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105969200

21 January 2018

High Affinity Binding of Inositol Phosphates and Phosphoinositides to the Pleckstrin Homology Domain of RAC/Protein Kinase B and Their Influence on Kinase Activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105969200

21 January 2018

Identifiers

10.1074/JBC.M105969200

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

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