(Q40774560)

23 September 2017

title

Down-modulation of type 1 interferon responses by receptor cross-competition for a shared Jak kinase (English)

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23 September 2017

S Pellegrini

6

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author name string

E Dondi

1

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23 September 2017

E Pattyn

2

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23 September 2017

G Lutfalla

3

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23 September 2017

X Van Ostade

4

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23 September 2017

G Uzé

5

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23 September 2017

J Tavernier

7

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23 September 2017

language of work or name

English

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publication date

15 October 2001

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Journal of Biological Chemistry

23 September 2017

published in

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23 September 2017

volume

276

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23 September 2017

issue

50

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23 September 2017

page(s)

47004-47012

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Alpha and beta interferons and their receptor and their friends and relations.

23 September 2017

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Jak-Stat signal transduction pathway through the eyes of cytokine class II receptor complexes

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Transcriptional responses to polypeptide ligands: the JAK-STAT pathway

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The taxonomy of developmental control in Caenorhabditis elegans

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Complete genomic organization and promoter analysis of the round-spotted pufferfish JAK1, JAK2, JAK3, and TYK2 genes

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The type I interferon receptor: structure, function, and evolution of a family business.

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The interleukin-12/interleukin-12-receptor system: role in normal and pathologic immune responses

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Direct binding to and tyrosine phosphorylation of the alpha subunit of the type I interferon receptor by p135tyk2 tyrosine kinase

21 January 2018

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Molecular characterization of an alpha interferon receptor 1 subunit (IFNaR1) domain required for TYK2 binding and signal transduction

21 January 2018

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Differential associations between the cytoplasmic regions of the interleukin-12 receptor subunits beta1 and beta2 and JAK kinases

21 January 2018

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Use of a selectable marker regulated by alpha interferon to obtain mutations in the signaling pathway

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Domains of interaction between alpha interferon and its receptor components

21 January 2018

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Dimerization of the interferon type I receptor IFNaR2-2 is sufficient for induction of interferon effector genes but not for full antiviral activity.

21 January 2018

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A functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunits

21 January 2018

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The amino-terminal region of Tyk2 sustains the level of interferon alpha receptor 1, a component of the interferon alpha/beta receptor

21 January 2018

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The cell surface expression level of the human interleukin-5 receptor alpha subunit determines the agonistic/antagonistic balance of the human interleukin-5 E13Q mutein.

21 January 2018

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Activation of the protein tyrosine kinase tyk2 by interferon alpha/beta

21 January 2018

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Interferon-alpha-dependent activation of Tyk2 requires phosphorylation of positive regulatory tyrosines by another kinase

21 January 2018

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Biological function and distribution of human interleukin-12 receptor beta chain

21 January 2018

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Transcription factor activity of STAT proteins: structural requirements and regulation by phosphorylation and interacting proteins

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Specific contribution of Tyk2 JH regions to the binding and the expression of the interferon alpha/beta receptor component IFNAR1.

21 January 2018

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Negative regulation of cytokine signaling pathways

21 January 2018

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Post-translational up-regulation of the cell surface-associated alpha component of the human type I interferon receptor during differentiation of peripheral blood monocytes: role in the biological response to type I interferon

21 January 2018

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A negative regulatory region in the intracellular domain of the human interferon-alpha receptor

21 January 2018

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Arginine methylation of STAT1 modulates IFNalpha/beta-induced transcription

21 January 2018

1 reference

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The soluble murine type I interferon receptor Ifnar-2 is present in serum, is independently regulated, and has both agonistic and antagonistic properties

21 January 2018

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How cells respond to interferons

21 January 2018

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Partial impairment of cytokine responses in Tyk2-deficient mice

21 January 2018

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Tyk2 plays a restricted role in IFN alpha signaling, although it is required for IL-12-mediated T cell function

21 January 2018

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Shared receptor components but distinct complexes for alpha and beta interferons

21 January 2018

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Selective loss of type I interferon-induced STAT4 activation caused by a minisatellite insertion in mouse Stat2.

21 January 2018

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The evolution of the type I interferon gene family in mammals

21 January 2018

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An unusual mechanism for ligand antagonism

21 January 2018

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Structural design and molecular evolution of a cytokine receptor superfamily

21 January 2018

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Characterization of Antihuman IFNAR-1 Monoclonal Antibodies: Epitope Localization and Functional Analysis

21 January 2018

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Erythropoietin receptor activation by a ligand-induced conformation change

21 January 2018

1 reference

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Cross talk between interferon-gamma and -alpha/beta signaling components in caveolar membrane domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104316200

21 January 2018

Identifiers

DOI

10.1074/JBC.M104316200

1 reference

23 September 2017

1 reference