(Q40775807)

23 September 2017

title

The tyrosine phosphatase SHP-2 is required for mediating phosphatidylinositol 3-kinase/Akt activation by growth factors (English)

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23 September 2017

2

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23 September 2017

5

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23 September 2017

Wu CJ

1

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23 September 2017

Feng GS

series ordinal

3

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23 September 2017

Johnson GR

series ordinal

4

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23 September 2017

Greene MI

series ordinal

6

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23 September 2017

language of work or name

English

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publication date

1 September 2001

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23 September 2017

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23 September 2017

volume

20

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23 September 2017

issue

42

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23 September 2017

page(s)

6018-6025

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Multiple requirements for SHPTP2 in epidermal growth factor-mediated cell cycle progression

23 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204699

A common requirement for the catalytic activity and both SH2 domains of SHP-2 in mitogen-activated protein (MAP) kinase activation by the ErbB family of receptors. A specific role for SHP-2 in map, but not c-Jun amino-terminal kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204699

SH2-containing phosphotyrosine phosphatase as a target of protein-tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204699

Phosphotyrosine phosphatases with SH2 domains: regulators of signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204699

Shp-2 tyrosine phosphatase: signaling one cell or many

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204699

Efficient cellular transformation by the Met oncoprotein requires a functional Grb2 binding site and correlates with phosphorylation of the Grb2-associated proteins, Cbl and Gab1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204699

A new tyrosine-phosphorylated 97-kDa adaptor protein mediates interleukin-2-induced association of SHP-2 with p85-phosphatidylinositol 3-kinase in human T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204699

Cloning of p97/Gab2, the major SHP2-binding protein in hematopoietic cells, reveals a novel pathway for cytokine-induced gene activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204699

Shp-2 mediates v-Src-induced morphological changes and activation of the anti-apoptotic protein kinase Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204699

Akt signaling: linking membrane events to life and death decisions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204699

A Grb2-associated docking protein in EGF- and insulin-receptor signalling

21 January 2018

1 reference

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A family of proteins that inhibit signalling through tyrosine kinase receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204699

Concerted activity of tyrosine phosphatase SHP-2 and focal adhesion kinase in regulation of cell motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204699

Constitutive activation of phosphatidylinositol 3-kinase by a naturally occurring mutant epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204699

The lipid phosphatase activity of PTEN is critical for its tumor supressor function

21 January 2018

1 reference

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Drug resistance of human glioblastoma cells conferred by a tumor-specific mutant epidermal growth factor receptor through modulation of Bcl-XL and caspase-3-like proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204699

Structure and function of SH2-domain containing tyrosine phosphatases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204699

A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204699

Regulation of early events in integrin signaling by protein tyrosine phosphatase SHP-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204699

Structural determinants of SHP-2 function and specificity in Xenopus mesoderm induction

21 January 2018

1 reference

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Trans receptor inhibition of human glioblastoma cells by erbB family ectodomains.

21 January 2018

1 reference

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Inhibition of a naturally occurring EGFR oncoprotein by the p185neu ectodomain: implications for subdomain contributions to receptor assembly.

21 January 2018

1 reference

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Genetic evidence that Shp-2 tyrosine phosphatase is a signal enhancer of the epidermal growth factor receptor in mammals

21 January 2018

1 reference

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Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

21 January 2018

1 reference

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Abnormal mesoderm patterning in mouse embryos mutant for the SH2 tyrosine phosphatase Shp-2.

21 January 2018

1 reference

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The Shp-2 tyrosine phosphatase has opposite effects in mediating the activation of extracellular signal-regulated and c-Jun NH2-terminal mitogen-activated protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204699

Signalling through the lipid products of phosphoinositide-3-OH kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204699

Activation of a phosphotyrosine phosphatase by tyrosine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204699

Inhibition of EGFR-mediated phosphoinositide-3-OH kinase (PI3-K) signaling and glioblastoma phenotype by signal-regulatory proteins (SIRPs)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204699

Protein-tyrosine phosphatase Shp-2 regulates cell spreading, migration, and focal adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204699

Mechanism of activation of protein kinase B by insulin and IGF-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204699

7 January 2021

Characterization of a novel tyrosine phosphorylated 100-kDa protein that binds to SHP-2 and phosphatidylinositol 3'-kinase in myeloid cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204699

7 January 2021

Mice mutant for Egfr and Shp2 have defective cardiac semilunar valvulogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204699

7 January 2021

Interleukin-3 induces association of the protein-tyrosine phosphatase SHP2 and phosphatidylinositol 3-kinase with a 100-kDa tyrosine-phosphorylated protein in hemopoietic cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204699

7 January 2021

SHP-1 regulates Lck-induced phosphatidylinositol 3-kinase phosphorylation and activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204699

7 January 2021

Domain-specific Interactions between the p185neuand Epidermal Growth Factor Receptor Kinases Determine Differential Signaling Outcomes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204699

7 January 2021

Formation of distinct signalling complexes involving phosphatidylinositol 3-kinase activity with stimulation of epidermal growth factor or insulin-like growth factor-I in human skin fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204699

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1204699

1 reference

Dimensions Publication ID

23 September 2017

1009617502

0 references

1 reference