(Q40781025)

23 September 2017

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title

Transgenic animals as models for human disease--report of an EC Study Group (English)

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23 September 2017

R Lathe

1

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author name string

J J Mullins

series ordinal

2

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23 September 2017

1 September 1993

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23 September 2017

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23 September 2017

2

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23 September 2017

5

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23 September 2017

286-299

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https://scigraph.springernature.com/pub.10.1007/bf01968841

23 September 2017

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cites work

A new vector for cloning large eukaryotic DNA segments in Escherichia coli

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FBF01968841

Testing an "in-out" targeting procedure for making subtle genomic modifications in mouse embryonic stem cells

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FBF01968841

Regionally restricted developmental defects resulting from targeted disruption of the mouse homeobox gene hox-1.5

21 January 2018

1 reference

12 December 2020

A position-effect assay for boundaries of higher order chromosomal domains

1 reference

12 December 2020

Hippocampal grafts derived from embryonic trisomy 16 mice exhibit amyloid (A4) and neurofibrillary pathology.

1 reference

12 December 2020

Embryonic stem cells as a model for cardiogenesis

1 reference

12 December 2020

Position-independent, high-level expression of the human beta-globin gene in transgenic mice

1 reference

12 December 2020

Preimplantation sexing and diagnosis of hypoxanthine phosphoribosyl transferase deficiency in mice by biochemical microassay

1 reference

12 December 2020

Some savage cuts in defence

1 reference

12 December 2020

Homeobox genes and congenital malformations

1 reference

12 December 2020

A yeast artificial chromosome covering the tyrosinase gene confers copy number-dependent expression in transgenic mice.

1 reference

12 December 2020

Cloning and stable maintenance of 300-kilobase-pair fragments of human DNA in Escherichia coli using an F-factor-based vector

1 reference

12 December 2020

Transgenic mice with inducible dwarfism.

1 reference

12 December 2020

Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E

1 reference

12 December 2020

Cre-stimulated recombination at loxP-containing DNA sequences placed into the mammalian genome

1 reference

12 December 2020

Atherogenesis in transgenic mice expressing human apolipoprotein(a)

1 reference

12 December 2020

Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells

1 reference

12 December 2020

Formation of beta-amyloid protein deposits in brains of transgenic mice

1 reference

12 December 2020

An exonic mutation in the HuP2 paired domain gene causes Waardenburg's syndrome

1 reference

12 December 2020

Transgenic mouse eggs with functional hamster sperm receptors in their zona pellucida

1 reference

12 December 2020

Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells

1 reference

12 December 2020

Interaction of DNA with nuclear scaffolds in vitro.

1 reference

12 December 2020

Waardenburg's syndrome patients have mutations in the human homologue of the Pax-3 paired box gene

1 reference

12 December 2020

The mutant vasopressin gene from diabetes insipidus (Brattleboro) rats is transcribed but the message is not efficiently translated

1 reference

12 December 2020

Homeotic transformations of murine vertebrae and concomitant alteration of Hox codes induced by retinoic acid

1 reference

12 December 2020

Correction of the genetic defect in hepatocytes from the Watanabe heritable hyperlipidemic rabbit.

1 reference

12 December 2020

Cystic fibrosis mouse with intestinal obstruction

1 reference

12 December 2020

Cystic fibrosis in the mouse by targeted insertional mutagenesis

1 reference

12 December 2020

A phenotype or not: targeting genes in the immune system

1 reference

12 December 2020

Analysis of relative mRNA levels and protein patterns in brains of rat strains bred for differing levels of emotionality

1 reference

12 December 2020

Generation and analysis of interleukin-4 deficient mice

1 reference

12 December 2020

High level expression of human apolipoprotein A-I in transgenic rats raises total serum high density lipoprotein cholesterol and lowers rat apolipoprotein A-I

1 reference

12 December 2020

Altering the genome by homologous recombination

1 reference

12 December 2020

Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy

1 reference

12 December 2020

splotch (Sp2H), a mutation affecting development of the mouse neural tube, shows a deletion within the paired homeodomain of Pax-3

1 reference

12 December 2020

A nuclear DNA attachment element mediates elevated and position-independent gene activity

1 reference

12 December 2020

Transgenic mice generated by pronuclear injection of a yeast artificial chromosome.

1 reference

12 December 2020

Fulminant hypertension in transgenic rats harbouring the mouse Ren-2 gene

1 reference

12 December 2020

Cloning of large segments of exogenous DNA into yeast by means of artificial chromosome vectors

1 reference

12 December 2020

Evaluation of 225 patients undergoing subzonal insemination for the procurement of fertilization in vitro

1 reference

12 December 2020

Drosophila P element integration in the mouse

1 reference

12 December 2020

Human gene therapy comes of age.

1 reference

12 December 2020

Mouse small eye results from mutations in a paired-like homeobox-containing gene

1 reference

12 December 2020

Human CD2 3'-flanking sequences confer high-level, T cell-specific, position-independent gene expression in transgenic mice

1 reference

12 December 2020

Separate elements cause lineage restriction and specify boundaries of Hox-1.1 expression

1 reference

12 December 2020

Introduction of a subtle mutation into the Hox-2.6 locus in embryonic stem cells

1 reference

12 December 2020

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

1 reference

12 December 2020

Efficient joining of large DNA fragments for transgenesis

1 reference

12 December 2020

Isolation of an active human transposable element

1 reference

12 December 2020

Nucleotide sequences of the human and mouse atrial natriuretic factor genes.

1 reference

12 December 2020

Neonatal hepatitis induced by alpha 1-antitrypsin: a transgenic mouse model

1 reference

12 December 2020

A distinct Hox code for the branchial region of the vertebrate head

1 reference

12 December 2020

Mouse embryonic stem cells and reporter constructs to detect developmentally regulated genes.

1 reference

12 December 2020

Cardiovascular research in transgenic animals

1 reference

12 December 2020

Efficient generation of functional transgenes by homologous recombination in murine zygotes

1 reference

12 December 2020

DNA-mediated genetic transformation of mouse embryos and bone marrow--a review

1 reference

12 December 2020

Cell Lines of the Pituitary Gonadotrope Lineage Derived by Targeted Oncogenesis in Transgenic Mice

1 reference

12 December 2020

Impaired long-term potentiation, spatial learning, and hippocampal development in fyn mutant mice

1 reference

12 December 2020

Expression of a candidate sex-determining gene during mouse testis differentiation.

1 reference

12 December 2020

Craniofacial abnormalities induced by ectopic expression of the homeobox gene Hox-1.1 in transgenic mice

1 reference

12 December 2020

The effect of salicylazosulphapyridine (sulphasalazine) on male fertility. A review

1 reference

12 December 2020

An animal model for cystic fibrosis made by gene targeting

1 reference

12 December 2020

Germ-line transformation of mice

1 reference

12 December 2020

Cloning and functional expression of a mouse gonadotropin-releasing hormone receptor

1 reference

12 December 2020

Alzheimer's disease. In search of the soluble

1 reference

12 December 2020

Chromosomal mapping of two genetic loci associated with blood-pressure regulation in hereditary hypertensive rats

1 reference

12 December 2020

Evidence for Drosophila P element transposase activity in mammalian cells and yeast

1 reference

12 December 2020

Recombinase-mediated gene activation and site-specific integration in mammalian cells

1 reference

12 December 2020

Atrial natriuretic factor-SV40 T antigen transgenes produce tumors and cardiac arrhythmias in mice

1 reference

12 December 2020

Direct derivation of conditionally immortal cell lines from an H-2Kb-tsA58 transgenic mouse

1 reference

12 December 2020

Germ-line transmission and expression of a human-derived yeast artificial chromosome

1 reference

12 December 2020

Overexpression of apolipoprotein E in transgenic mice: marked reduction in plasma lipoproteins except high density lipoprotein and resistance against diet-induced hypercholesterolemia

1 reference

12 December 2020

Blastocyst implantation depends on maternal expression of leukaemia inhibitory factor

1 reference

12 December 2020

Binary system for regulating transgene expression in mice: targeting int-2 gene expression with yeast GAL4/UAS control elements.

1 reference

12 December 2020

undulated, a mutation affecting the development of the mouse skeleton, has a point mutation in the paired box of Pax 1

1 reference

12 December 2020

Two putative active centers in human angiotensin I-converting enzyme revealed by molecular cloning

1 reference

12 December 2020

Debrisoquine hydroxylase gene polymorphism and susceptibility to Parkinson's disease

1 reference

12 December 2020

Immortalization of hypothalamic GnRH neurons by genetically targeted tumorigenesis

1 reference

12 December 2020

Genetic mapping of a gene causing hypertension in the stroke-prone spontaneously hypertensive rat

1 reference

12 December 2020

Impaired spatial learning in alpha-calcium-calmodulin kinase II mutant mice

1 reference

12 December 2020

Cystic fibrosis mice have arrived!

1 reference

12 December 2020

Rescuing transgene expression by co-integration

1 reference

12 December 2020

The prevention of thymic lymphomas in transgenic mice by human O6-alkylguanine-DNA alkyltransferase

1 reference

12 December 2020

Induction of theCyp1a-1dioxin-responsive enhancer in transgenic mice

1 reference

12 December 2020

Heritable formation of pancreatic beta-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes

1 reference

12 December 2020

1 reference

12 December 2020

Male development of chromosomally female mice transgenic for Sry.

1 reference

12 December 2020

Species specificity of renin kinetics in transgenic rats harboring the human renin and angiotensinogen genes

1 reference

12 December 2020

Sequence and functional expression of the GABA A receptor shows a ligand-gated receptor super-family.

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF01968841

1 reference

PubMed ID

8242097

Dimensions Publication ID

23 September 2017

0 references

1 reference

PubMed ID

8242097