(Q40802962)

English

Establishment of the transformants expressing human cytochrome P450 subtypes in HepG2, and their applications on drug metabolism and toxicology

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scholarly article

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Europe PubMed Central

23 September 2017

Establishment of the transformants expressing human cytochrome P450 subtypes in HepG2, and their applications on drug metabolism and toxicology (English)

1 reference

Europe PubMed Central

23 September 2017

author name string

Yoshitomi S

1

1 reference

Europe PubMed Central

23 September 2017

Ikemoto K

2

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Europe PubMed Central

23 September 2017

Takahashi J

3

1 reference

Europe PubMed Central

23 September 2017

Miki H

4

1 reference

Europe PubMed Central

23 September 2017

Namba M

5

1 reference

Europe PubMed Central

23 September 2017

Asahi S

6

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Europe PubMed Central

23 September 2017

language of work or name

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publication date

1 June 2001

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Europe PubMed Central

23 September 2017

Toxicology in Vitro

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Europe PubMed Central

23 September 2017

15

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23 September 2017

245-256

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Europe PubMed Central

23 September 2017

3

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Europe PubMed Central

23 September 2017

Estradiol metabolism by complementary deoxyribonucleic acid-expressed human cytochrome P450s

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based on heuristic

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Cytotoxicity and apoptosis produced by cytochrome P450 2E1 in Hep G2 cells

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Stable expression of human cytochrome P4502E1 in HepG2 cells: characterization of catalytic activities and production of reactive oxygen intermediates

1 reference

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7 January 2021

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Cytotoxicity testing of 114 compounds by the determination of the protein content in Hep G2 cell cultures.

1 reference

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Molecular studies on the toxifying effects by genetically engineered cytochromes P450.

1 reference

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inferred from DOI database lookup

The influence of culture medium composition on drug metabolising enzyme activities of the human liver derived Hep G2 cell line

1 reference

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7 January 2021

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Merits and limitations of recombinant models for the study of human P450-mediated drug metabolism and toxicity: an intralaboratory comparison.

1 reference

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High catalytic activity of human cytochrome P450 co-expressed with human NADPH-cytochrome P450 reductase in Escherichia coli

1 reference

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Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen

1 reference

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Catalytic properties of the human cytochrome P450 2E1 produced by cDNA expression in mammalian cells

1 reference

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inferred from DOI database lookup

Acetaminophen activation by human liver cytochromes P450IIE1 and P450IA2

1 reference

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inferred from DOI database lookup

Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers, and inhibitors

1 reference

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7 January 2021

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Development and validation of alternative metabolic systems for mutagenicity testing in short-term assays

1 reference

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Oxidative stress and cytotoxicity induced by ferric-nitrilotriacetate in HepG2 cells that express cytochrome P450 2E1.

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Genetically engineered cells stably expressing cytochrome P450 and their application to mutagen assays

1 reference

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Stable expression of human cytochrome P450 1A1 cDNA in V79 Chinese hamster cells and metabolic activation of benzo[a]pyrene

1 reference

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Metabolism of oxazaphosphorines

1 reference

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based on heuristic

inferred from DOI database lookup

Oxidation of acetaminophen to N-acetyl-p-aminobenzoquinone imine by human CYP3A4

1 reference

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inferred from DOI database lookup

Steroid hormone hydroxylase specificities of eleven cDNA-expressed human cytochrome P450s

1 reference

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based on heuristic

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Ethanol cytotoxicity to a transfected HepG2 cell line expressing human cytochrome P4502E1.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0887-2333(01)00011-X

1 reference

Europe PubMed Central

23 September 2017

1 reference

Europe PubMed Central

23 September 2017

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