(Q40818461)

24 September 2017

Tpl-2 induces apoptosis by promoting the assembly of protein complexes that contain caspase-9, the adapter protein Tvl-1, and procaspase-3. (English)

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24 September 2017

6

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24 September 2017

Patriotis C

1

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24 September 2017

Russeva MG

2

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24 September 2017

Lin JH

3

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24 September 2017

Srinivasula SM

4

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24 September 2017

Markova DZ

5

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24 September 2017

Makris A

7

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24 September 2017

Alnemri ES

8

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24 September 2017

Tsichlis PN

9

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24 September 2017

1 May 2001

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Journal of Cellular Physiology

24 September 2017

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24 September 2017

187

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24 September 2017

2

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24 September 2017

176-187

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Regulation of apoptotic protease activating factor-1 oligomerization and apoptosis by the WD-40 repeat region

24 September 2017

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Death receptors: signaling and modulation

21 January 2018

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TPL-2 kinase regulates the proteolysis of the NF-kappaB-inhibitory protein NF-kappaB1 p105

21 January 2018

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Apoptosis: checkpoint at the mitochondrial frontier.

21 January 2018

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Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development

21 January 2018

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Tpl-2 is an oncogenic kinase that is activated by carboxy-terminal truncation

21 January 2018

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Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product

21 January 2018

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Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

21 January 2018

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Transcriptional activation by tetracyclines in mammalian cells

21 January 2018

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Mitochondria and apoptosis

21 January 2018

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Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis

21 January 2018

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Release of caspase-9 from mitochondria during neuronal apoptosis and cerebral ischemia

21 January 2018

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Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

21 January 2018

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

21 January 2018

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The ankyrin repeat-containing adaptor protein Tvl-1 is a novel substrate and regulator of Raf-1

21 January 2018

1 reference

A gene encoding a novel RFX-associated transactivator is mutated in the majority of MHC class II deficiency patients

21 January 2018

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FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).

21 January 2018

1 reference

RFX-B is the gene responsible for the most common cause of the bare lymphocyte syndrome, an MHC class II immunodeficiency

21 January 2018

1 reference

Tumor progression locus 2 (Tpl-2) encodes a protein kinase involved in the progression of rodent T-cell lymphomas and in T-cell activation

21 January 2018

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Tpl-2 acts in concert with Ras and Raf-1 to activate mitogen-activated protein kinase

21 January 2018

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Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation

21 January 2018

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Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

21 January 2018

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Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization

21 January 2018

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CLAP, a novel caspase recruitment domain-containing protein in the tumor necrosis factor receptor pathway, regulates NF-kappaB activation and apoptosis

21 January 2018

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Tumor necrosis factor's cytotoxic activity is signaled by the p55 TNF receptor

21 January 2018

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21 January 2018

Caspases: enemies within

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The Tpl-2 protooncoprotein activates the nuclear factor of activated T cells and induces interleukin 2 expression in T cell lines.

21 January 2018

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Hsp60 accelerates the maturation of pro-caspase-3 by upstream activator proteases during apoptosis

21 January 2018

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Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

21 January 2018

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Apaf1 is required for mitochondrial pathways of apoptosis and brain development

21 January 2018

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Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

21 January 2018

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An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

21 January 2018

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Hidden powers of the mitochondria

21 January 2018

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Caspase activation involves the formation of the aposome, a large (approximately 700 kDa) caspase-activating complex

21 January 2018

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Activation of caspases triggered by cytochrome c in vitro

21 January 2018

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Tpl-2 induces IL-2 expression in T-cell lines by triggering multiple signaling pathways that activate NFAT and NF-kappaB

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JCP.1066

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24 September 2017

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