(Q40819546)

English

Cytoplasmic domains determine signal specificity, cellular routing characteristics and influence ligand binding of epidermal growth factor and insulin receptors

scientific article published on October 1989

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scholarly article

1 reference

Europe PubMed Central

24 September 2017

Cytoplasmic domains determine signal specificity, cellular routing characteristics and influence ligand binding of epidermal growth factor and insulin receptors (English)

1 reference

Europe PubMed Central

24 September 2017

1 reference

based on heuristic

inferred from title

Annemarie Honegger

3

1 reference

Europe PubMed Central

24 September 2017

Joseph Schlessinger

4

object named as

Schlessinger J

1 reference

Europe PubMed Central

24 September 2017

author name string

Riedel H

1

1 reference

Europe PubMed Central

24 September 2017

Dull TJ

2

1 reference

Europe PubMed Central

24 September 2017

Ullrich A

5

1 reference

Europe PubMed Central

24 September 2017

language of work or name

0 references

publication date

1 October 1989

1 reference

Europe PubMed Central

24 September 2017

The EMBO Journal

1 reference

Europe PubMed Central

24 September 2017

8

1 reference

Europe PubMed Central

24 September 2017

2943-2954

1 reference

Europe PubMed Central

24 September 2017

10

1 reference

Europe PubMed Central

24 September 2017

Electrophoretic resolution of three major insulin receptor structures with unique subunit stoichiometries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

24 September 2017

Internalization and degradation of macrophage Fc receptors bound to polyvalent immune complexes

1 reference

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24 September 2017

Isolation and expression of an altered mouse dihydrofolate reductase cDNA.

1 reference

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24 September 2017

Phorbol esters modulate insulin receptor phosphorylation and insulin action in cultured hepatoma cells

1 reference

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24 September 2017

Insulin receptors: binding kinetics and structure-function relationship of insulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

24 September 2017

Kinetic properties and sites of autophosphorylation of the partially purified insulin receptor from hepatoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

24 September 2017

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

24 September 2017

Down-regulation of the epidermal growth factor receptor in KB cells is due to receptor internalization and subsequent degradation in lysosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

24 September 2017

Down regulation of epidermal growth factor receptors: direct demonstration of receptor degradation in human fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

24 September 2017

Plasmid-Directed Synthesis of Hepatitis B Surface Antigen in Monkey Cells

1 reference

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24 September 2017

Epidermal Growth Factor: Mechanisms of Action

1 reference

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24 September 2017

Insulin receptor is an insulin-dependent tyrosine protein kinase: copurification of insulin-binding activity and protein kinase activity to homogeneity from human placenta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

24 September 2017

Journey to the Center of the Cell: Role of the Receptosome

1 reference

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24 September 2017

Endocytosis of Peptide Hormones and Other Ligands

1 reference

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24 September 2017

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

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24 September 2017

A new technique for the assay of infectivity of human adenovirus 5 DNA

1 reference

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24 September 2017

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

24 September 2017

Protein kinase C directly phosphorylates the insulin receptor in vitro and reduces its protein-tyrosine kinase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

24 September 2017

A mutant epidermal growth factor receptor with defective protein tyrosine kinase is unable to stimulate proto-oncogene expression and DNA synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

24 September 2017

Epidermal growth factor induces rapid, reversible aggregation of the purified epidermal growth factor receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

24 September 2017

Heterologous transmembrane signaling by a human insulin receptor-v-ros hybrid in Chinese hamster ovary cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

24 September 2017

Molecular analysis of signal transduction by growth factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

24 September 2017

Ligand activation of overexpressed epidermal growth factor receptors transforms NIH 3T3 mouse fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

24 September 2017

Replacement of lysine residue 1030 in the putative ATP-binding region of the insulin receptor abolishes insulin- and antibody-stimulated glucose uptake and receptor kinase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

24 September 2017

Growth factor receptor tyrosine kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

24 September 2017

Insulin stimulates phosphorylation of a 120-kDa glycoprotein substrate (pp120) for the receptor-associated protein kinase in intact H-35 hepatoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

24 September 2017

Receptor-mediated endocytosis of epidermal growth factor by rat hepatocytes: receptor pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

24 September 2017

Uptake of insulin and other ligands into receptor-rich endocytic components of target cells: the endosomal apparatus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

24 September 2017

The molecular mechanism of insulin action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

24 September 2017

Tumor-promoting phorbol diesters cause the phosphorylation of epidermal growth factor receptors in normal human fibroblasts at threonine-654

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

24 September 2017

Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

24 September 2017

Increased expression of the putative growth factor receptor p185HER2 causes transformation and tumorigenesis of NIH 3T3 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

24 September 2017

The human insulin receptor cDNA: the structural basis for hormone-activated transmembrane signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

24 September 2017

Functional analysis of the ligand binding site of EGF-receptor utilizing chimeric chicken/human receptor molecules.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

24 September 2017

A rapid alkaline extraction procedure for screening recombinant plasmid DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

24 September 2017

Epidermal Growth Factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

24 September 2017

Tumor-Promoting Phorbol Esters Inhibit Binding of Epidermal Growth Factor to Cellular Receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

24 September 2017

Direct visualization of binding, aggregation, and internalization of insulin and epidermal growth factor on living fibroblastic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

24 September 2017

Molecular mechanism of mitogen action: processing of receptor induced by epidermal growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

24 September 2017

Insulin and epidermal growth factor. Human fibroblast receptors related to deoxyribonucleic acid synthesis and amino acid uptake

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

24 September 2017

Evidence for recycling of insulin receptors in isolated rat adipocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

15 June 2018

Modulation of Epidermal Growth Factor Receptors on 3T3 Cells by Platelet-Derived Growth Factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

15 June 2018

An endogenous substrate for the insulin receptor-associated tyrosine kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

15 June 2018

Kinetics of insulin receptor internalization and recycling in adipocytes. Shunting of receptors to a degradative pathway by inhibitors of recycling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

15 June 2018

Epidermal growth factor stimulates tyrosine phosphorylation of specific proteins in permeabilized human fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

15 June 2018

Overexpression of the human EGF receptor confers an EGF-dependent transformed phenotype to NIH 3T3 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

15 June 2018

Epidermal-growth-factor-dependent transformation by a human EGF receptor proto-oncogene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

15 June 2018

Point mutation at the ATP binding site of EGF receptor abolishes protein-tyrosine kinase activity and alters cellular routing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

15 June 2018

Expression in rat fibroblasts of a human transforming growth factor-alpha cDNA results in transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

15 June 2018

A mutant insulin receptor with defective tyrosine kinase displays no biologic activity and does not undergo endocytosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

15 June 2018

Five enzymes of the glycolytic pathway serve as substrates for purified epidermal-growth-factor-receptor kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

15 June 2018

Epidermal growth factor mimics insulin effects in rat hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

15 June 2018

Monoclonal antibodies reacting with multiple epitopes on the human insulin receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

15 June 2018

Similar effects of platelet-derived growth factor and epidermal growth factor on the phosphorylation of tyrosine in cellular proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

19 August 2018

Antibodies against a synthetic peptide as a probe for the kinase activity of the avian EGF receptor and v-erbB protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

19 August 2018

Autophosphorylation and protein kinase C phosphorylation of the epidermal growth factor receptor. Effect on tyrosine kinase activity and ligand binding affinity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=401363

2 December 2018

Resolution of high and low affinity epidermal growth factor receptors. Inhibition of high affinity component by low temperature, cycloheximide, and phorbol esters

1 reference

https://pubmed.ncbi.nlm.nih.gov/2583088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification of insulin receptor with full binding activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/2583088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor stimulates glycogen synthesis in fetal rat hepatocytes: comparison with the glycogenic effects of insulin-like growth factor I and insulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/2583088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A chimaeric receptor allows insulin to stimulate tyrosine kinase activity of epidermal growth factor receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/2583088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C phosphorylation of the EGF receptor at a threonine residue close to the cytoplasmic face of the plasma membrane

1 reference

https://pubmed.ncbi.nlm.nih.gov/2583088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The kinetics of tyrosine phosphorylation by the purified epidermal growth factor receptor kinase of A-431 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2583088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-stimulated phosphorylation of the insulin receptor precursor

1 reference

https://pubmed.ncbi.nlm.nih.gov/2583088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human insulin receptors mutated at the ATP-binding site lack protein tyrosine kinase activity and fail to mediate postreceptor effects of insulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/2583088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative ultrastructural analysis of receptor-mediated insulin uptake into adipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2583088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin receptor regulation and desensitization in rat hepatoma cells. The loss of the oligomeric forms of the receptor correlates with the change in receptor affinity

1 reference

https://pubmed.ncbi.nlm.nih.gov/2583088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased phosphorylation of ribosomal protein S6 following microinjection of insulin receptor-kinase into Xenopus oocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2583088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of a calcium-dependent 35-kilodalton substrate for the epidermal growth factor receptor/kinase from A-431 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2583088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Self-phosphorylation of epidermal growth factor receptor: evidence for a model of intermolecular allosteric activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/2583088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin binds to and promotes the phosphorylation of a Mr 210 000 component of its receptor in detergent extracts of rat liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2583088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor and potent phorbol tumor promoters induce epidermal growth factor receptor phosphorylation in a similar but distinctively different manner in human epidermoid carcinoma A431 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2583088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

C-kinase phosphorylates the epidermal growth factor receptor and reduces its epidermal growth factor-stimulated tyrosine protein kinase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/2583088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subunit arrangement of insulin receptors in hepatoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2583088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin rapidly stimulates tyrosine phosphorylation of a Mr-185,000 protein in intact cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2583088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A monoclonal antibody to the human epidermal growth factor receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/2583088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An insulin-stimulated (ribosomal S6) protein kinase from soluble extracts of H4 hepatoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2583088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biologically active phorbol esters specifically alter affinity of epidermal growth factor membrane receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/2583088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The structure of insulin receptor and its subunits. Evidence for multiple nonreduced forms and a 210,000 possible proreceptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/2583088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

1 reference

Europe PubMed Central

24 September 2017

1 reference

Europe PubMed Central

24 September 2017

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