(Q40820975)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11248363%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

title

Anti-herpesvirus activity of (1'S,2'R)-9-[[1',2'-bis(hydroxymethyl)-cycloprop-1'-yl]methyl] x guanine (A-5021) in vitro and in vivo (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11248363%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1

1 reference

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5 November 2019

Lieve Naesens

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11248363%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

author name string

C Ying

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11248363%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

L De Bolle

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11248363%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

E De Clercq

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11248363%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

publication date

1 February 2001

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11248363%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11248363%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

volume

49

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11248363%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11248363%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

page(s)

115-120

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11248363%20AND%20SRC:MED&resulttype=core&format=json

The Epstein-Barr virus thymidine kinase does not phosphorylate ganciclovir or acyclovir and demonstrates a narrow substrate specificity compared to the herpes simplex virus type 1 thymidine kinase

5 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2800%2900144-3

7 January 2021

Human herpesvirus 8 open reading frame 21 is a thymidine and thymidylate kinase of narrow substrate specificity that efficiently phosphorylates zidovudine but not ganciclovir

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2800%2900144-3

7 January 2021

Avoidance of bone marrow suppression using A-5021 as a nucleoside analog for retrovirus-mediated herpes simplex virus type I thymidine kinase gene therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2800%2900144-3

7 January 2021

Antiherpesvirus activities of (1'S,2'R)-9-[[1',2'-bis(hydroxymethyl)cycloprop-1'-yl]methyl]guanine (A-5021) in cell culture

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2800%2900144-3

7 January 2021

Evaluation of anti-herpesvirus activity of (1'S,2'R)-9-[[1',2'-bis(hydroxymethyl)cycloprop-1'-yl]methyl]- guanine (A-5021) in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2800%2900144-3

7 January 2021

Sensitivity of Kaposi's sarcoma-associated herpesvirus replication to antiviral drugs. Implications for potential therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2800%2900144-3

7 January 2021

Inducible expression of human hepatitis B virus (HBV) in stably transfected hepatoblastoma cells: a novel system for screening potential inhibitors of HBV replication.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2800%2900144-3

7 January 2021

Comparison of two bromovinyl nucleoside analogs, 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil and E-5-(2-bromovinyl)-2'-deoxyuridine, with acyclovir in inhibition of Epstein-Barr virus replication

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2800%2900144-3

7 January 2021

Inhibitory effects of novel nucleoside and nucleotide analogues on Epstein-Barr virus replication

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2800%2900144-3

7 January 2021

Efficacy of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)-cytosine and 9-(1,3-dihydroxy-2-propoxymethyl)-guanine in the treatment of intracerebral murine cytomegalovirus infections in immunocompetent and immunodeficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2800%2900144-3

7 January 2021

In vitro and in vivo inhibition of murine gamma herpesvirus 68 replication by selected antiviral agents.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2800%2900144-3

7 January 2021

Mode of action of (1'S,2'R)-9-[[1',2'-bis(hydroxymethyl) cycloprop-1'-yl]methyl]guanine (A-5021) against herpes simplex virus type 1 and type 2 and varicella-zoster virus.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2800%2900144-3

7 January 2021

Synthesis and antiviral activity of novel acyclic nucleosides: discovery of a cyclopropyl nucleoside with potent inhibitory activity against herpesviruses

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2800%2900144-3

7 January 2021

Use of digoxigenin-labelled probes for the quantitation of HBV-DNA in antiviral drug evaluation

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2800%2900144-3

7 January 2021

Inhibition of the replication of the DNA polymerase M550V mutation variant of human hepatitis B virus by adefovir, tenofovir, L-FMAU, DAPD, penciclovir and lobucavir

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2800%2900144-3

7 January 2021

10.1016/S0166-3542(00)00144-3

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11248363%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference