(Q40823566)

24 September 2017

1 reference

title

Adenovirus-E1A proteins transform cells by sequestering regulatory proteins (English)

1 reference

24 September 2017

1 reference

D S Peeper

1

1 reference

24 September 2017

A Zantema

series ordinal

2

1 reference

24 September 2017

publication date

1 April 1993

1 reference

Molecular Biology Reports

24 September 2017

published in

1 reference

24 September 2017

volume

17

1 reference

24 September 2017

issue

3

1 reference

24 September 2017

page(s)

197-207

1 reference

Different functional domains of the adenovirus E1A gene are involved in regulation of host cell cycle products

24 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FBF00986728

Association of adenovirus early-region 1A proteins with cellular polypeptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00986728

Antibodies specific for the human retinoblastoma protein identify a family of related polypeptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00986728

The retinoblastoma protein physically associates with the human cdc2 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00986728

Activation of human cyclin-dependent kinases in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00986728

Promoter-specific trans-activation by the adenovirus E1A12S product involves separate E1A domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00986728

Sequences in E1A proteins of human adenovirus 5 required for cell transformation, repression of a transcriptional enhancer, and induction of proliferating cell nuclear antigen.

21 January 2018

1 reference

12 December 2020

Immortalization of primary epithelial cells requires first- and second-exon functions of adenovirus type 5 12S.

1 reference

12 December 2020

1 reference

12 December 2020

Adenovirus E1A proteins can dissociate heteromeric complexes involving the E2F transcription factor: a novel mechanism for E1A trans-activation

1 reference

12 December 2020

The retinoblastoma protein is phosphorylated on multiple sites by human cdc2

1 reference

12 December 2020

Cell cycle regulation of histone H1 kinase activity associated with the adenoviral protein E1A.

1 reference

12 December 2020

Regulation of retinoblastoma protein functions by ectopic expression of human cyclins

1 reference

12 December 2020

Cyclin A is required at two points in the human cell cycle

1 reference

12 December 2020

Comparison of nucleotide sequences of the early E1a regions for subgroups A, B and C of human adenoviruses

1 reference

12 December 2020

Cyclin: a protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage division

1 reference

12 December 2020

A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F

1 reference

12 December 2020

Association of cdk2 Kinase with the Transcription Factor E2F During S Phase

1 reference

12 December 2020

Structure-function analysis of the human papillomavirus type 16 E7 oncoprotein

1 reference

12 December 2020

Detection of cellular proteins associated with human adenovirus type 5 early region 1A polypeptides.

1 reference

12 December 2020

Adenovirus E1B 19-kilodalton protein overcomes the cytotoxicity of E1A proteins

1 reference

12 December 2020

Interaction of p107 with cyclin A independent of complex formation with viral oncoproteins

1 reference

12 December 2020

The role of cyclin B in meiosis I.

1 reference

12 December 2020

The adenovirus E4 17-kilodalton protein complexes with the cellular transcription factor E2F, altering its DNA-binding properties and stimulating E1A-independent accumulation of E2 mRNA.

1 reference

12 December 2020

Two regions of the adenovirus early region 1A proteins are required for transformation.

1 reference

12 December 2020

Dephosphorylation and activation of Xenopusp34 cdc2 protein kinase during the cell cycle

1 reference

12 December 2020

Creative blocks: cell-cycle checkpoints and feedback controls

1 reference

12 December 2020

Isolation of the human cdk2 gene that encodes the cyclin A- and adenovirus E1A-associated p33 kinase

1 reference

12 December 2020

Cyclin A is required in S phase in normal epithelial cells.

1 reference

12 December 2020

A cellular protein that competes with SV40 T antigen for binding to the retinoblastoma gene product

1 reference

12 December 2020

Adenovirus E1a ras cooperation activity is separate from its positive and negative transcription regulatory functions

1 reference

12 December 2020

The role of cyclin synthesis and degradation in the control of maturation promoting factor activity

1 reference

12 December 2020

Adenovirus E1A is associated with a serine/threonine protein kinase

1 reference

12 December 2020

The transcription factor E2F interacts with the retinoblastoma product and a p107-cyclin A complex in a cell cycle-regulated manner

1 reference

12 December 2020

Phosphorylation at Thr167 is required for Schizosaccharomyces pombe p34cdc2 function

1 reference

12 December 2020

Retinoblastoma cancer suppressor gene product is a substrate of the cell cycle regulator cdc2 kinase

1 reference

12 December 2020

TGF-beta 1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains.

1 reference

12 December 2020

A novel function of the transforming domain of E1a: repression of AP-1 activity

1 reference

12 December 2020

SV40 large T antigen binds preferentially to an underphosphorylated member of the retinoblastoma susceptibility gene product family

1 reference

12 December 2020

Cell cycle regulation of the human cdc2 gene

1 reference

12 December 2020

Transcription activation by the adenovirus E1a protein

1 reference

12 December 2020

Oncogenes and signal transduction

1 reference

12 December 2020

Expression of recessive alleles by chromosomal mechanisms in retinoblastoma

1 reference

12 December 2020

Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis

1 reference

12 December 2020

An adenovirus E4 gene product trans-activates E2 transcription and stimulates stable E2F binding through a direct association with E2F.

1 reference

12 December 2020

Differential phosphorylation of vertebrate p34cdc2 kinase at the G1/S and G2/M transitions of the cell cycle: identification of major phosphorylation sites

1 reference

12 December 2020

Activation of the E2F transcription factor in adenovirus-infected cells involves E1A-dependent stimulation of DNA-binding activity and induction of cooperative binding mediated by an E4 gene product

1 reference

12 December 2020

The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle

1 reference

12 December 2020

Transcriptional and Transforming Activities of the Adenovirus E1A Proteins

1 reference

12 December 2020

Cdc2 protein kinase is complexed with both cyclin A and B: evidence for proteolytic inactivation of MPF

1 reference

12 December 2020

An adenovirus E1A protein domain activates transcription in vivo and in vitro in the absence of protein synthesis

1 reference

12 December 2020

Differential effects of the adenovirus E1A oncogene on members of the AP-1 transcription factor family

1 reference

12 December 2020

The retinoblastoma susceptibility gene product undergoes cell cycle-dependent dephosphorylation and binding to and release from SV40 large T.

1 reference

12 December 2020

E1A induces phosphorylation of the retinoblastoma protein independently of direct physical association between the E1A and retinoblastoma products

1 reference

12 December 2020

Mutational analysis of autonomously functioning trans-activating peptides encoded by adenovirus E1A: evidence for two subdomains.

1 reference

12 December 2020

Domains of the adenovirus E1A protein required for oncogenic activity are also required for dissociation of E2F transcription factor complexes

1 reference

12 December 2020

Human cyclins A and B1 are differentially located in the cell and undergo cell cycle-dependent nuclear transport

1 reference

12 December 2020

Simian virus 40 large-T antigen expresses a biological activity complementary to the p300-associated transforming function of the adenovirus E1A gene products

1 reference

12 December 2020

Partial transformation of primary rat cells by the leftmost 4.5% fragment of adenovirus 5 DNA.

1 reference

12 December 2020

Cloning of cDNAs for cellular proteins that bind to the retinoblastoma gene product

1 reference

12 December 2020

The cellular 107K protein that binds to adenovirus E1A also associates with the large T antigens of SV40 and JC virus

1 reference

12 December 2020

E1A-dependent trans-activation of the human MYC promoter is mediated by the E2F factor

1 reference

12 December 2020

Transforming growth factor beta 1 suppression of c-myc gene transcription: role in inhibition of keratinocyte proliferation

1 reference

12 December 2020

A first exon-encoded domain of E1A sufficient for posttranslational modification, nuclear-localization, and induction of adenovirus E3 promoter expression in Xenopus oocytes

1 reference

12 December 2020

Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product

1 reference

12 December 2020

Expression, purification, and functional characterization of adenovirus 5 and 12 E1A proteins produced in insect cells

1 reference

12 December 2020

An N-terminal transformation-governing sequence of SV40 large T antigen contributes to the binding of both p110Rb and a second cellular protein, p120.

1 reference

12 December 2020

Cyclin synthesis drives the early embryonic cell cycle

1 reference

12 December 2020

Purification and characterization of human papillomavirus type 16 E7 protein with preferential binding capacity to the underphosphorylated form of retinoblastoma gene product

1 reference

12 December 2020

Retinoblastoma growth suppressor and a 300-kDa protein appear to regulate cellular DNA synthesis

1 reference

12 December 2020

Identification of separate domains in the adenovirus E1A gene for immortalization activity and the activation of virus early genes

1 reference

12 December 2020

Nonfunctional mutants of the retinoblastoma protein are characterized by defects in phosphorylation, viral oncoprotein association, and nuclear tethering

1 reference

12 December 2020

Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties

1 reference

12 December 2020

Effects of Ad5 E1A mutant viruses on the cell cycle in relation to the binding of cellular proteins including the retinoblastoma protein and cyclin A

1 reference

12 December 2020

An N-terminal region of adenovirus E1a essential for cell transformation and induction of an epithelial cell growth factor

1 reference

12 December 2020

The adenovirus E4 gene, in addition to the E1A gene, is important for trans-activation of E2 transcription and for E2F activation

1 reference

12 December 2020

Adenovirus E1A protein paradigm viral transactivator

1 reference

12 December 2020

Induction of AP-1 DNA-binding activity and c-fos mRNA by the adenovirus 243R E1A protein and cyclic AMP requires domains necessary for transformation

1 reference

12 December 2020

The E2F transcription factor is a cellular target for the RB protein

1 reference

12 December 2020

cdc2-like kinase is associated with the retinoblastoma protein

1 reference

12 December 2020

Isolation and characterization of insertion mutants in E1A of adenovirus type 5

1 reference

12 December 2020

Evidence that the G1-S and G2-M transitions are controlled by different cdc2 proteins in higher eukaryotes

1 reference

12 December 2020

The regions of the retinoblastoma protein needed for binding to adenovirus E1A or SV40 large T antigen are common sites for mutations

1 reference

12 December 2020

Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product

1 reference

12 December 2020

Growth inhibition by TGF-beta linked to suppression of retinoblastoma protein phosphorylation

1 reference

12 December 2020

The repression of the growth factor-inducible genes JE, c-myc and stromelysin by adenovirus E1A is mediated by conserved region 1

1 reference

12 December 2020

Interaction between human cyclin A and adenovirus E1A-associated p107 protein

1 reference

12 December 2020

Adenovirus promoters and E1A transactivation

1 reference

12 December 2020

Adenovirus E1A activation domain binds the basic repeat in the TATA box transcription factor

1 reference

12 December 2020

Failure to phosphorylate the retinoblastoma gene product in senescent human fibroblasts

1 reference

12 December 2020

Co-purification of p34cdc2/p58cyclin A proline-directed protein kinase and the retinoblastoma tumor susceptibility gene product: interaction of an oncogenic serine/threonine protein kinase with a tumor-suppressor protein

1 reference

12 December 2020

Molecular cloning, chromosomal mapping, and expression of the cDNA for p107, a retinoblastoma gene product-related protein

1 reference

12 December 2020

Human cyclin A and the retinoblastoma protein interact with similar but distinguishable sequences in the adenovirus E1A gene product

1 reference

12 December 2020

Mechanisms of transformation by polyoma virus middle T antigen

1 reference

12 December 2020

Differential activation of the E2F transcription factor by the adenovirus EIa and EIV products in F9 cells

1 reference

12 December 2020

The amino-terminal region of the adenovirus serotype 5 E1a protein performs two separate functions when expressed in primary baby rat kidney cells

1 reference

12 December 2020

A 60 kd cdc2-associated polypeptide complexes with the E1A proteins in adenovirus-infected cells

1 reference

12 December 2020

Cellular targets for transformation by the adenovirus E1A proteins

1 reference

12 December 2020

When the products of oncogenes and anti-oncogenes meet

1 reference

12 December 2020

Mutational analysis of the adenovirus E1a gene: the role of transcriptional regulation in transformation

1 reference

12 December 2020

Enhanced ras oncogene mediated cell transformation and tumorigenesis by adenovirus 2 mutants lacking the C-terminal region of E1a protein.

1 reference

12 December 2020

Human cdc2 protein kinase is a major cell-cycle regulated tyrosine kinase substrate

1 reference

12 December 2020

A nexus between Oct-4 and E1A: implications for gene regulation in embryonic stem cells

1 reference

12 December 2020

trans-dominant mutants of E1A provide genetic evidence that the zinc finger of the trans-activating domain binds a transcription factor

1 reference

12 December 2020

Cell cycle regulation of the E2F transcription factor involves an interaction with cyclin A.

1 reference

12 December 2020

A cyclin A-protein kinase complex possesses sequence-specific DNA binding activity: p33cdk2 is a component of the E2F-cyclin A complex.

1 reference

12 December 2020

Dephosphorylation and activation of a p34cdc2/cyclin B complex in vitro by human CDC25 protein

1 reference

12 December 2020

1 reference

12 December 2020

The retinoblastoma protein is phosphorylated during specific phases of the cell cycle

1 reference

12 December 2020

Evidence for interaction of different eukaryotic transcriptional activators with distinct cellular targets

1 reference

12 December 2020

Complete transformation by adenovirus 2 requires both E1A proteins

1 reference

12 December 2020

Independent binding of the retinoblastoma protein and p107 to the transcription factor E2F.

1 reference

12 December 2020

Cyclin activation of p34cdc2.

1 reference

12 December 2020

Inactivation of the p34cdc2-cyclin B complex by the human WEE1 tyrosine kinase

1 reference

12 December 2020

E1a regions of the human adenoviruses and of the highly oncogenic simian adenovirus 7 are closely related

1 reference

12 December 2020

The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product

1 reference

12 December 2020

Analysis of E1A-mediated growth regulation functions: binding of the 300-kilodalton cellular product correlates with E1A enhancer repression function and DNA synthesis-inducing activity

1 reference

12 December 2020

Use of deletion and point mutants spanning the coding region of the adenovirus 5 E1A gene to define a domain that is essential for transcriptional activation

1 reference

12 December 2020

G1/S phosphorylation of the retinoblastoma protein is associated with an altered affinity for the nuclear compartment

1 reference

12 December 2020

An adenovirus E1a protein region required for transformation and transcriptional repression

1 reference

12 December 2020

The 289-amino acid E1A protein of adenovirus binds zinc in a region that is important for trans-activation

1 reference

12 December 2020

The clam embryo protein cyclin A induces entry into M phase and the resumption of meiosis in Xenopus oocytes

1 reference

12 December 2020

Modulation of transformation of primary epithelial cells by the second exon of the Ad5 E1A12S gene

1 reference

12 December 2020

Direct interaction between adenovirus E1A protein and the TATA box binding transcription factor IID

1 reference

12 December 2020

Interactions between cell growth-regulating domains in the products of the adenovirus E1A oncogene

1 reference

12 December 2020

Activation of cdc2 protein kinase during mitosis in human cells: cell cycle-dependent phosphorylation and subunit rearrangement

1 reference

12 December 2020

Adenovirus E1A coding sequences that enable ras and pmt oncogenes to transform cultured primary cells

1 reference

12 December 2020

Identification of a cellular transcription factor involved in E1A trans-activation

1 reference

12 December 2020

Genetic dissection of the transactivating domain of the E1a 289R protein of adenovirus type 2

1 reference

12 December 2020

Mapping of functional domains in adenovirus E1A proteins

1 reference

12 December 2020

Adenovirus E1A makes two distinct contacts with the retinoblastoma protein

1 reference

12 December 2020

Cooperativity in transactivation between retinoic acid receptor and TFIID requires an activity analogous to E1A

1 reference

12 December 2020

Lytic and transforming functions of individual products of the adenovirus E1A gene.

1 reference

12 December 2020

Human cyclin A is adenovirus E1A-associated protein p60 and behaves differently from cyclin B.

1 reference

12 December 2020

Functional domains of adenovirus type 5 E1a proteins.

1 reference

12 December 2020

The adenovirus E1A transforming protein activates the proliferating cell nuclear antigen promoter via an activating transcription factor site

1 reference

12 December 2020

Identification of cellular proteins that can interact specifically with the T/ElA-binding region of the retinoblastoma gene product

1 reference

12 December 2020

Growth factor induction by the adenovirus type 5 E1A 12S protein is required for immortalization of primary epithelial cells

1 reference

12 December 2020

Mapping of cellular protein-binding sites on the products of early-region 1A of human adenovirus type 5.

1 reference

12 December 2020

Independent transformation activity by adenovirus-5 E1A-conserved regions 1 or 2 mutants.

1 reference

12 December 2020

Role of E2F transcription factor in E1A-mediated trans activation of cellular genes

1 reference

12 December 2020

Retinoblastoma protein switches the E2F site from positive to negative element

1 reference

12 December 2020

Induction of transforming growth factor beta 1 resistance by the E1A oncogene requires binding to a specific set of cellular proteins.

1 reference

12 December 2020

The carboxy-terminal exon of the adenovirus E1A protein is required for E4F-dependent transcription activation

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF00986728

1 reference

24 September 2017

1 reference